Mm01266490_g1

• Gene Symbol: Hes5
• Gene Name: hairy and enhancer of split 5 (Drosophila)
• Gene Aliases: bHLHb38
• Chromosome Location: Chr.4: 154958680 - 154962372 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hes5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010419.4	NP_034549.1	1 - 2	129		73
GenBank mRNA	AK078170.1	-	1 - 2			73
	AK087508.1	-	1 - 2	130		73
	AK139390.1	-	1 - 2	131		73
	BC099863.1	-	1 - 2	81	40039952	73
	BC099864.1	-	1 - 2	81	40039951	73
	BC099865.1	-	1 - 2	81	40039949	73
	BC103539.1	-	1 - 2	79	40039948	73

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0400002062.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hes5

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cell adhesion
Notch signaling pathway
smoothened signaling pathway
multicellular organism development
nervous system development
brain development
positive regulation of cell proliferation
oligodendrocyte development
telencephalon development
glial cell fate commitment
forebrain radial glial cell differentiation
neural tube development
central nervous system myelination
cell differentiation
positive regulation of BMP signaling pathway
regulation of myelination
auditory receptor cell differentiation
positive regulation of tyrosine phosphorylation of Stat3 protein
auditory receptor cell fate determination
camera-type eye development
regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
cell maturation
positive regulation of smooth muscle cell proliferation
astrocyte differentiation
negative regulation of astrocyte differentiation
negative regulation of oligodendrocyte differentiation
regulation of neurogenesis
cartilage development
neuronal stem cell population maintenance
negative regulation of stem cell differentiation
negative regulation of pro-B cell differentiation
negative regulation of forebrain neuron differentiation
negative regulation of inner ear receptor cell differentiation

Function(s)

transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
protein binding
transcription factor binding
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400016978.mm.1	NM_010419.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400016978.mm.1	NM_010419.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0400016978.mm.1	TC0400002062.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400016975.mm.1	NM_010419.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400016975.mm.1	NM_010419.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0400016975.mm.1	TC0400002062.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400016977.mm.1	NM_010419.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400016977.mm.1	NM_010419.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0400016977.mm.1	TC0400002062.mm.1	MTA TC