Rn00597229_g1 Best Coverage

• Gene Symbol: Pycard
• Gene Name: PYD and CARD domain containing
• Gene Aliases: Asc
• Chromosome Location: Chr.1: 199438029 - 199439062 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pycard
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_172322.1	NP_758825.1	2 - 3	324		80
GenBank mRNA	AB053165.1	-	2 - 3	324		80
	FQ226280.1	-	2 - 3	482		80
	FQ227755.1	-	2 - 3	482		80

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0100006728.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protease, 3' Most, Detect Genomic DNA, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pycard

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

myeloid dendritic cell activation
activation of innate immune response
positive regulation of defense response to virus by host
myeloid dendritic cell activation involved in immune response
positive regulation of antigen processing and presentation of peptide antigen via MHC class II
positive regulation of adaptive immune response
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
response to bacterium
regulation of autophagy
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of actin filament polymerization
regulation of protein stability
negative regulation of NF-kappaB transcription factor activity
interleukin-1 beta production
negative regulation of interferon-beta production
positive regulation of interferon-gamma production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
tumor necrosis factor-mediated signaling pathway
positive regulation of activated T cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
macropinocytosis
positive regulation of JNK cascade
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
positive regulation of phagocytosis
defense response to Gram-negative bacterium
positive regulation of T cell activation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
defense response to virus
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
negative regulation of protein serine/threonine kinase activity
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of chemokine secretion
positive regulation of release of cytochrome c from mitochondria
positive regulation of T cell migration
positive regulation of interleukin-8 secretion
positive regulation of interleukin-6 secretion
positive regulation of cysteine-type endopeptidase activity
positive regulation of interleukin-10 secretion
positive regulation of extrinsic apoptotic signaling pathway
regulation of intrinsic apoptotic signaling pathway

Function(s)

protease binding
protein binding
Pyrin domain binding
protein homodimerization activity
ion channel binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P226597	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	871016	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P226597	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P226597	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P226597	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P226597	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P292141	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	76883	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10726111	-	-
Affymetrix Rat Gene 1.0 ST Array	10726110	-	-
Affymetrix Rat Gene 1.0 ST Array	10726109	-	-
Affymetrix Rat Gene 1.1 ST Array	10726108	-	-
Rat Genome 230 2.0 Array	1389873_at	-	-
Rat Genome 230 2.0 Array	1389873_PM_at	-	-
Affymetrix HT Rat Focus Array	1389873_at	-	-
Affymetrix HT Rat Focus Array	1389873_PM_at	-	-
Affymetrix Rat Clariom S Assay	PSR0100053112.rn.1	TC0100006728.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0100053113.rn.1	TC0100006728.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0100053111.rn.1	TC0100006728.rn.1	RTA TC
Rat Expression Set 230	1389873_PM_at	-	-
Rat Expression Set 230	1389873_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10726108	-	-
Rat Genome U34 Set	rc_AA851245_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21821093	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1372174	-	-
RatRef-12 Expression BeadChip	ILMN_62540	-	-