Tocris
Explore a range of Tocris organic compounds, small molecules, enzymes, and other specialty chemicals and reagents to support your research and testing needs.
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Tocris Bioscience™ MitoBrilliant 646
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Universal red fluorescent mitochondrial stain for both live and fixed cells
| Target | Mitochondria Dyes and Probes |
|---|---|
| Content And Storage | Store at -20°C |
Tocris Bioscience™ Yoda 1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Piezo1 channel activator
| Target | Other Calcium Channel Activators |
|---|---|
| CAS | 448947-81-7 |
| Purity | >99% |
| Chemical Name or Material | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C13H8Cl2N4S2 |
| Formula Weight | 355.27 |
Tocris Bioscience™ NTRC 824
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective non-peptide NTS2 antagonist
| Target | Neurotensin Receptor Antagonists |
|---|---|
| CAS | 1623002-61-8 |
| Purity | >98% |
| Chemical Name or Material | N-[2-[5-[[(4-Methylphenyl)sulfonyl]amino]-3-(2,2,2-trifluoroacetyl)-1H-indol-1-yl]acetyl]-L-leucine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H26F3N3O6S |
| Formula Weight | 553.55 |
Tocris Bioscience™ Blasticidin S HCl
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Antibiotic; selection reagent for bis, bsr and BSD transformed cells
Tocris Bioscience™ BIIE 0246 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
| Target | NPY Receptor Antagonists |
|---|---|
| CAS | 2624332-04-1 |
| Purity | 0.98 |
| Chemical Name or Material | N-[(1 S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5 H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C49H57N11O6.HCl |
Tocris Bioscience™ N-Acetylcysteine amide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Glutathione (GSH) precursor; neuroprotective
| Target | Additional Antioxidant Compounds |
|---|---|
| CAS | 38520-57-9 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C5H10N2O2S |
| Formula Weight | 162.21 |
Tocris Bioscience™ Hydroxychloroquine sulfate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Autophagy inhibitor; also TLR9 inhibitor
| Target | Autophagy-related Compounds |
|---|---|
| CAS | 747-36-4 |
| Purity | >99% |
| Chemical Name or Material | 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H28ClN3O5S |
| Formula Weight | 433.95 |
Tocris Bioscience™ HBC 530
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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GFP fluorophore mimic for imaging RNA in live cells; activated by binding to Pepper aptamers; suitable for confocal and two-photon microscopy
Tocris Bioscience™ Polyamine Supplement x1000 (lyophilized)
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
Tocris Bioscience™ DOPE
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Liposome/lipoplex transfection enhancer
Tocris Bioscience™ DFHBI 1T
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Mimic of GFP fluorophore for imaging RNA in living cells
Tocris Bioscience™ PR 619
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Broad spectrum DUB inhibitor
| CAS | 2645-32-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 10mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | PR 619 |
| Recommended Storage | Store at -20°C |
| Synonym | 2,6-Diamino-3,5-dithiocyanopyridine |
| Molecular Formula | C7H5N5S2 |
| Formula Weight | 223.28 |
Tocris Bioscience™ WIC1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Inhibitor of Wnt/β-catenin signaling
| Target | beta-Catenin |
|---|---|
| CAS | 943083-58-7 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2 H-1-benzopyran-3-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H23N3O3 |
Tocris Bioscience™ CU CPT 22
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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CAS: 1416324-85-0 Molecular Formula: C19H22O7
| CAS | 1416324-85-0 |
|---|---|
| Molecular Formula | C19H22O7 |
Tocris Bioscience™ Linifanib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
| Target | PDGF R beta |
|---|---|
| CAS | 796967-16-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-(3-Amino-1 H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H18FN5O |