Tocris

Dynasore, Tocris Bioscience™

Dynasore, Tocris Bioscience™

CAS: 304448-55-3 Molecular Formula: C18H14N2O4 Molecular Weight (g/mol): 322.32 MDL Number: MFCD00292551 InChI Key: NRQJUIHYFNUXFT-UHFFFAOYSA-N Synonym: 2-naphthalenecarboxylicacid, 3-hydroxy-, 2-3,4-dihydroxyphenyl methylene hydrazide, 3-hydroxy-n'-3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene methyl naphthalene-2-carbohydrazide, dynamin inhibitor i, dynasore, dynasore monohydrate, n'-1e-3,4-dihydroxyphenyl methylidene-3-hydroxynaphthalene-2-carbohydrazide, n'-3,4-dihydroxybenzylidene-3-hydroxy-2-naphthohydrazide, n'-3,4-dihydroxyphenyl methylidene-3-hydroxynaphthalene-2-carbohydrazide PubChem CID: 6739924 IUPAC Name: 3-hydroxy-N'-[(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]naphthalene-2-carbohydrazide SMILES: OC1=CC(=CNNC(=O)C2=CC3=CC=CC=C3C=C2O)C=CC1=O

(±)-Blebbistatin, Tocris Bioscience™ <img src=

(±)-Blebbistatin, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 674289-55-5 Molecular Formula: C18H16N2O2 Molecular Weight (g/mol): 292.338 InChI Key: LZAXPYOBKSJSEX-UHFFFAOYSA-N Synonym: +--blebbistatin, +/--blebbistatin, +/-bebbistatin, --blebbistcitin, 1-phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo 2.3-b-7-methylquinolin-4-one, 3a-hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4h-pyrrolo 2,3-b quinolin-4-one, 3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo 2,3-b quinolin-4-one, 3a-hydroxy-6-methyl-1-phenyl-2h,3h-pyrrolo 2,3-b quinolin-4-one, blebbistatin, inverted exclamation marka-blebbistatin PubChem CID: 3476986 ChEBI: CHEBI:75379 IUPAC Name: 3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one SMILES: CC1=CC2=C(C=C1)N=C3C(C2=O)(CCN3C4=CC=CC=C4)O

Nutlin-3, Tocris Bioscience™

Nutlin-3, Tocris Bioscience™

CAS: 548472-68-0 Molecular Formula: C30H30Cl2N4O4 Molecular Weight (g/mol): 581.494 InChI Key: BDUHCSBCVGXTJM-UHFFFAOYSA-N Synonym: +/--nutlin3, 2-piperazinone,4-4r,5s-4,5-bis 4-chlorophenyl-4,5-dihydro-2-4-methoxy-2-1-methylethoxy phenyl-1h-imidazol-1-yl carbonyl-,rel, 4-4,5-bis 4-chlorophenyl-2-2-isopropoxy-4-methoxyphenyl-4,5-dihydro-1h-imidazole-1-carbonyl piperazin-2-one, 4-4,5-bis 4-chlorophenyl-2-4-methoxy-2-propan-2-yloxy phenyl-4,5-dihydro-1h-imidazol-1-yl carbonyl piperazin-2-one, 4-4,5-bis 4-chlorophenyl-2-4-methoxy-2-propan-2-yloxyphenyl-4,5-dihydroimidazole-1-carbonyl piperazin-2-one, 4-4,5-bis 4-chlorophenyl-4,5-dihydro-2-4-methoxy-2-1-methylethoxy phenyl-1h-imidazol-1-yl carbonyl-2-piperazinone, mdm2 antagonist, nutlin-3, racemic, nutlin, nutlin 3, nutlin-3 PubChem CID: 216345 IUPAC Name: 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one SMILES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

NKH 477, Tocris Bioscience™

NKH 477, Tocris Bioscience™

CAS: 138605-00-2 Molecular Formula: C27H43NO8 Molecular Weight (g/mol): 509.64 InChI Key: RSOZZQTUMVBTMR-XGUNBQNXSA-N Synonym: 3r,4ar,5s,6s,6as,10s,10ar,10bs-5-acetyloxy-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2h-benzo f chromen-6-yl 3-dimethylamino propanoate, beta-alanine, n,n-dimethyl-, 3r,4ar,5s,6s,6as,10s,10ar,10bs-5-acetyloxy-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1h-naphtho 2,1-b pyran-6-yl ester, colforsin dapropate, colforsin dapropate hcl, colforsin daropate, colforsin daropate hcl PubChem CID: 444029 IUPAC Name: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-acetyloxy-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] 3-(dimethylamino)propanoate SMILES: CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)OC(=O)CCN(C)C

EC 23, Tocris Bioscience™

EC 23, Tocris Bioscience™

CAS: 104561-41-3 Molecular Formula: C23H24O2 Molecular Weight (g/mol): 332.443 InChI Key: OQVLOWLEEHYBJH-UHFFFAOYSA-N Synonym: 4-2-1,1,4,4-tetramethyltetralin-6-yl ethynyl benzoic acid, 4-2-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl ethynyl, 4-2-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl ethynyl benzoic acid, 4-2-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl ethynyl benzoic acid, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl ethynyl benzoic acid, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylethynyl benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphth-2-yl ethynyl-benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphth-2-yl-ethynyl-benzoic acid, unii-vsdtydjdjj, vsdtydjdjj PubChem CID: 10314719 IUPAC Name: 4-[2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)ethynyl]benzoic acid SMILES: CC1(CCC(C2=C1C=CC(=C2)C#CC3=CC=C(C=C3)C(=O)O)(C)C)C

PPADS tetrasodium salt, Tocris Bioscience™

PPADS tetrasodium salt, Tocris Bioscience™

CAS: 192575-19-2 Molecular Formula: C14H10N3Na4O12PS2 Molecular Weight (g/mol): 599.296 InChI Key: KURWUCJJNVPCHT-UHFFFAOYSA-J Synonym: 6-2,4-bis sodiooxysulfonyl phenylazo pyridoxal 5'-phosphoric acid disodium salt, ppads sodium salt PubChem CID: 101086948 IUPAC Name: tetrasodium;4-[[4-formyl-6-methyl-5-oxido-3-(phosphonatooxymethyl)pyridin-2-yl]diazenyl]-3-sulfobenzenesulfonate SMILES: CC1=C(C(=C(C(=N1)N=NC2=C(C=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)O)COP(=O)([O-])[O-])C=O)[O-].[Na+].[Na+].[Na+].[Na+]

JZL 195, Tocris Bioscience™

JZL 195, Tocris Bioscience™

CAS: 1210004-12-8 Molecular Formula: C24H23N3O5 Molecular Weight (g/mol): 433.464 InChI Key: QNYRAEKLMNDRFY-UHFFFAOYSA-N Synonym: 4-3-phenoxyphenyl methyl-1-piperazinecarboxylic acid 4-nitrophenyl ester, 4-nitrophenyl 4-3-phenoxybenzyl piperazine-1-carboxylate, 4-nitrophenyl 4-3-phenoxyphenyl methyl piperazine-1-carboxylate, d06udn, jzl hplc PubChem CID: 46232606 IUPAC Name: (4-nitrophenyl) 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate SMILES: C1CN(CCN1CC2=CC(=CC=C2)OC3=CC=CC=C3)C(=O)OC4=CC=C(C=C4)[N+](=O)[O-]

CD 437, Tocris Bioscience™ <img src=

CD 437, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 125316-60-1 Molecular Formula: C27H26O3 Molecular Weight (g/mol): 398.502 InChI Key: LDGIHZJOIQSHPB-UHFFFAOYSA-N Synonym: 2-naphthalenecarboxylicacid, 6-4-hydroxy-3-tricyclo 3.3.1.13,7 dec-1-ylphenyl, 6-3-1-adamantyl-4-hydroxyphenyl naphthalene-2-carboxylic acid, 6-3-1-adamantyl-4-hydroxyphenyl-2-naphthalene carboxylic acid, 6-3-1-adamantyl-4-hydroxyphenyl-2-naphthalenecarboxylic acid, 6-4-hydroxy-3-tricyclo 3.3.1.1 3,7 dec-1-ylphenyl-2-naphthalenecarboxylic acid, ahpn, apoptosis activator vi, chembl1180, o-demethylated adapalene, o-desmethyl adapalene PubChem CID: 135411 IUPAC Name: 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid SMILES: C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O

AIM 100, Tocris Bioscience™

AIM 100, Tocris Bioscience™

CAS: 873305-35-2 Molecular Formula: C23H21N3O2 Molecular Weight (g/mol): 371.44 InChI Key: XNFHHOXCDUAYSR-SFHVURJKSA-N Synonym: 5,6-diphenyl-4-s-tetrahydrofuran-2-yl-methyl amino furo 2,3-d pyrimidine, 5,6-diphenyl-n-2s-tetrahydro-2-furanyl methyl furo 2,3-d pyrimidin-4-amine, 5,6-diphenyl-n-2s-tetrahydrofuran-2-yl methyl furo 2,3-d pyrimidin-4-amine, n-2s-oxolan-2-ylmethyl-5,6-diphenylfuro 2,3-d pyrimidin-4-amine, s-5,6-diphenyl-n-tetrahydrofuran-2-yl methyl furo 2,3-d pyrimidin-4-amine PubChem CID: 11501591 IUPAC Name: N-[[(2S)-oxolan-2-yl]methyl]-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine SMILES: C1CC(OC1)CNC2=C3C(=C(OC3=NC=N2)C4=CC=CC=C4)C5=CC=CC=C5

KL 001, Tocris Bioscience™

KL 001, Tocris Bioscience™

CAS: 309928-48-1 Molecular Formula: C21H22N2O4S Molecular Weight (g/mol): 398.477 InChI Key: OQAFDLPAPSSOHY-UHFFFAOYSA-N Synonym: 10.14272/oqafdlpapssohy-uhfffaoysa-n, 3-carbazol-9-yl-2-hydroxypropyl 2-furylmethyl methylsulfonyl amine, cbmicro_005790, doi:10.14272/oqafdlpapssohy-uhfffaoysa-n, n-3-9h-carbazol-9-yl-2-hydroxypropyl-n-furan-2-ylmethyl methanesulfonamide, n-3-carbazol-9-yl-2-hydroxy-propyl-n-2-furfuryl methanesulfonamide, n-3-carbazol-9-yl-2-hydroxy-propyl-n-furan-2-ylmethyl-methanesulfonamide, n-3-carbazol-9-yl-2-hydroxypropyl-n-furan-2-ylmethyl methanesulfonamide PubChem CID: 2888648 IUPAC Name: N-(3-carbazol-9-yl-2-hydroxypropyl)-N-(furan-2-ylmethyl)methanesulfonamide SMILES: CS(=O)(=O)N(CC1=CC=CO1)CC(CN2C3=CC=CC=C3C4=CC=CC=C42)O

A 77636 hydrochloride, Tocris Bioscience™

A 77636 hydrochloride, Tocris Bioscience™

CAS: 145307-34-2 Molecular Formula: C20H28ClNO3 Molecular Weight (g/mol): 365.898 InChI Key: BWHPNJVKFAPVOG-UHFFFAOYSA-N Synonym: (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride PubChem CID: 16069211 IUPAC Name: 3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol;hydrochloride SMILES: C1C2CC3CC1CC(C2)(C3)C4CC5=C(C=CC(=C5O)O)C(O4)CN.Cl

(-)-Quinpirole hydrochloride, Tocris Bioscience™ <img src=

(-)-Quinpirole hydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 85798-08-9 Molecular Formula: C13H22ClN3 Molecular Weight (g/mol): 255.79 InChI Key: HJHVRVJTYPKTHX-HTMVYDOJSA-N Synonym: --4ar,8ar-4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1h-pyrazolo 3,4-g quinoline monohydrochloride, --quinpirole hydrochloride, dsstox_cid_25519, dsstox_gsid_45519, dsstox_rid_80926, quinpirole hcl, quinpirole hydrochloride, quinpirole hydrochloride usan, unii-t6i2w5v2k1 PubChem CID: 55397 IUPAC Name: (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrazolo[3,4-g]quinoline;hydrochloride SMILES: CCCN1CCCC2C1CC3=C(C2)NN=C3.Cl

Torin 1, Tocris Bioscience™

Torin 1, Tocris Bioscience™

CAS: 1222998-36-8 Molecular Formula: C35H28F3N5O2 Molecular Weight (g/mol): 607.64 MDL Number: MFCD18782653 InChI Key: AKCRNFFTGXBONI-UHFFFAOYSA-N Synonym: 1-4-4-1-oxopropyl-1-piperazinyl-3-trifluoromethyl phenyl-9-3-quinolinyl benzo h-1,6-naphthyridin-2 1h-one, 1-4-4-1-oxopropyl-1-piperazinyl-3-trifluoromethyl phenyl-9-3-quinolinyl-benzo h-1,6-naphthyridin-2 1h-one, 1-4-4-propanoylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one, 1-4-4-propanoylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6-naphthyridin-2-one, 1-4-4-propionylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one, d0h0hr, torin 1, torin-1, torin1 PubChem CID: 49836027 ChEBI: CHEBI:84327 IUPAC Name: 1-[4-(4-propanoylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)-1H,2H-benzo[h]1,6-naphthyridin-2-one SMILES: CCC(=O)N1CCN(CC1)C1=C(C=C(C=C1)N1C(=O)C=CC2=C1C1=CC(=CC=C1N=C2)C1=CN=C2C=CC=CC2=C1)C(F)(F)F

MNI 137, Tocris Bioscience™

MNI 137, Tocris Bioscience™

CAS: 946619-21-2 Molecular Formula: C15H9BrN4O Molecular Weight (g/mol): 341.168 InChI Key: KMKZCMKOSAKVGY-UHFFFAOYSA-N Synonym: 4-8-bromo-2,3-dihydro-2-oxo-1h-1,5-benzodiazepin-4-yl-2-pyridinecarbonitrile PubChem CID: 25210562 IUPAC Name: 4-(8-bromo-2-oxo-1,3-dihydro-1,5-benzodiazepin-4-yl)pyridine-2-carbonitrile SMILES: C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N

NS 3623, Tocris Bioscience™ <img src=

NS 3623, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 343630-41-1 Molecular Formula: C15H10BrF3N6O Molecular Weight (g/mol): 427.185 InChI Key: JXPULDIATMTIIN-UHFFFAOYSA-N Synonym: 1-4-bromo-2-1h-1,2,3,4-tetrazol-5-yl phenyl-3-3-trifluoromethyl phenyl urea, 1-4-bromo-2-2h-tetrazol-5-yl phenyl-3-3-trifluoromethyl phenyl urea, d0jy2k, herg potassium channel openers arrhythmia, herg potassium channel openers arrhythmia , neurosearch, i kr agonists arrhythmia , neurosearch, n-4-bromo-2-1h-tetrazol-5-yl-phenyl-n'-3'-trifluoromethylphenyl urea, n-4-bromo-2-1h-tetrazol-5-yl-phenyl-n'-3-trifluoromethyl phenyl-urea, rapid delayed-rectifier current activators acquired long qt syndrome , neruosearch PubChem CID: 9954236 IUPAC Name: 1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea SMILES: C1=CC(=CC(=C1)NC(=O)NC2=C(C=C(C=C2)Br)C3=NNN=N3)C(F)(F)F

TPMPA, Tocris Bioscience™

TPMPA, Tocris Bioscience™

CAS: 182485-36-5 Molecular Formula: C6H12NO2P Molecular Weight (g/mol): 161.141 InChI Key: MFUKVPOVVKKLRQ-UHFFFAOYSA-N Synonym: 1,2,5,6-tetrahydropyridin-4-yl methylphosphinic acid hydrate, 1,2,5,6-tetrahydropyridin-4-yl methylphosphinsaure, biomol-nt_000236, methyl 1,2,3,6-tetrahydropyridin-4-yl phosphinic acid, methyl 1,2,3,6-tetrahydropyridinium-4-yl phosphinate, p-methyl-p-1,2,3,6-tetrahydro-4-pyridinyl phosphinic acid, phosphinic acid, p-methyl-p-1,2,3,6-tetrahydro-4-pyridinyl, tpmpa, tpmpa mi, unii-tr7i0800l2 PubChem CID: 5521 IUPAC Name: methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid SMILES: CP(=O)(C1=CCNCC1)O

Maraviroc, Tocris Bioscience™ <img src=

Maraviroc, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 376348-65-1 Molecular Formula: C29H41F2N5O Molecular Weight (g/mol): 513.678 InChI Key: GSNHKUDZZFZSJB-HLMSNRGBSA-N Synonym: 3h maraviroc, celsentri, celsentri tm, maraviroc, maraviroc usan, mvc, pro 140 & maraviroc, selzentry, selzentry tm, unii-md6p741w8a PubChem CID: 3002977 IUPAC Name: 4,4-difluoro-N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide SMILES: CC1=NN=C(N1C2CC3CCC(C2)N3CCC(C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C

Dihydro-β-erythroidine hydrobromide, Tocris Bioscience™ <img src=

Dihydro-β-erythroidine hydrobromide, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 29734-68-7 Molecular Formula: C16H22BrNO3 Molecular Weight (g/mol): 356.26 InChI Key: GFIGWAJEIMHJJB-LINSIKMZSA-N Synonym: 2s,13bs-2-methoxy-2,3,5,6,8,9,10,13-octahydro-1h,12h-benzo i pyrano 3,4-g indolizin-12-one hydrobromide, 3, 3beta-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide, a-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide, dh?e, dihydro-?-erythroidine hydrobromide, dihydro-beta-erythroidine hydrobromide, unii-ns1u03gc05 PubChem CID: 11957537 SMILES: COC1CC=C2CCN3C2(C1)C4=C(CC3)COC(=O)C4.Br

A 438079 hydrochloride, Tocris Bioscience™

A 438079 hydrochloride, Tocris Bioscience™

CAS: 899431-18-6 Molecular Formula: C13H10Cl3N5 Molecular Weight (g/mol): 342.608 InChI Key: MBTJFFMIPPMRGR-UHFFFAOYSA-N Synonym: 3-5-2,3-dichlorophenyl tetrazol-1-yl methyl pyridine;hydrochloride, 3-5-2,3-dichlorophenyl-1,2,3,4-tetrazol-1-yl methyl pyridine hydrochloride, 3-5-2,3-dichlorophenyl-1h-tetrazol-1-yl methyl, 3-5-2,3-dichlorophenyl-1h-tetrazol-1-yl methyl pyridine hydrochloride, a 438079 hydrochloride, c13h9cl2n5.clh, hcl PubChem CID: 11688742 IUPAC Name: 3-[[5-(2,3-dichlorophenyl)tetrazol-1-yl]methyl]pyridine;hydrochloride SMILES: C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl

EIPA, Tocris Bioscience™

EIPA, Tocris Bioscience™

CAS: 1154-25-2 Molecular Formula: C11H18ClN7O Molecular Weight (g/mol): 299.76 MDL Number: MFCD00151710 InChI Key: QDERNBXNXJCIQK-UHFFFAOYSA-N Synonym: 3-amino-n-aminoiminomethyl-6-chloro-5-ethyl 1-methylethyl amino-2-pyrazinecarboxamide, 5-ethylisopropyl amiloride, 5-n-ethyl-n-isopropyl amiloride, 5-n-ethyl-n-isopropyl-amiloride, eipa, ethyl isopropyl amiloride, ethylisopropylamiloride, n-amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide, unii-vw50ce070t PubChem CID: 1795 IUPAC Name: 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide SMILES: CCN(C(C)C)C1=NC(N)=C(N=C1Cl)C(=O)N=C(N)N

XAV 939, Tocris Bioscience™

XAV 939, Tocris Bioscience™

CAS: 284028-89-3 Molecular Formula: C14H11F3N2OS Molecular Weight (g/mol): 312.31 InChI Key: KLGQSVMIPOVQAX-UHFFFAOYSA-N Synonym: 2-4-trifluoromethyl phenyl-1,5,7,8-tetrahydro-4h-thiopyrano 4,3-d pyrimidin-4-one, 2-4-trifluoromethyl phenyl-1,5,7,8-tetrahydrothiopyrano 4,3-d pyrimidin-4-one, 2-4-trifluoromethyl phenyl-1h,5h,7h,8h-thiopyrano 4,3-d pyrimidin-4-one, 2-4-trifluoromethyl phenyl-3h,5h,7h,8h-thiopyrano 4,3-d pyrimidin-4-one, 2-4-trifluoromethyl phenyl-5h,7h,8h-thiopyrano 4,3-d pyrimidin-4-ol, 2-4-trifluoromethyl phenyl-7,8-dihydro-5h-thiino 4,3-d pyrimidin-4-ol, 2-4-trifluoromethyl phenyl-7,8-dihydro-5h-thiopyrano 4,3-d pyrimidin-4-ol, 3,5,7,8-tetrahydro-2-4-trifluoromethyl phenyl-4h-thiopyrano 4,3-d pyrimidin-4-one PubChem CID: 2726824 ChEBI: CHEBI:62878 IUPAC Name: 2-[4-(trifluoromethyl)phenyl]-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one SMILES: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F

Cyclopiazonic acid, Tocris Bioscience™ <img src=

Cyclopiazonic acid, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 18172-33-3 Molecular Formula: C20H20N2O3 Molecular Weight (g/mol): 336.391 InChI Key: SZINUGQCTHLQAZ-AFAVFJNCSA-N Synonym: 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, alpha-cyclopiazonate, alpha-cyclopiazonic acid, ambotzls-1020, ccris 4942, cyclopiazonic acid, cyclopyazonic acid, unii-x9tly4580z PubChem CID: 54711281 SMILES: CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O

Clozapine N-oxide, Tocris Bioscience™

Clozapine N-oxide, Tocris Bioscience™

CAS: 34233-69-7 Molecular Formula: C18H19ClN4O Molecular Weight (g/mol): 342.827 InChI Key: WYRDWWAASBTJLM-UHFFFAOYSA-N Synonym: chembl1688, clozapine n-oxide, clozapine n-oxide cno, clozapine-n-oxide, mza8bk588j, n-oxyclozapine, oguczbiqsyywef-uhfffaoysa-n, unii-mza8bk588j PubChem CID: 2819 IUPAC Name: 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine SMILES: C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]

endo-IWR 1, Tocris Bioscience™ <img src=

endo-IWR 1, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 1127442-82-3 Molecular Formula: C25H19N3O3 Molecular Weight (g/mol): 409.445 InChI Key: ZGSXEXBYLJIOGF-HRQSHJORSA-N Synonym: iwr-1, iwr-1-endo PubChem CID: 91885421 SMILES: C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6

QX 314 chloride, Tocris Bioscience™

QX 314 chloride, Tocris Bioscience™

CAS: 5370-01-4 Molecular Formula: C11H18ClNO Molecular Weight (g/mol): 215.72 InChI Key: NFEIBWMZVIVJLQ-UHFFFAOYNA-N Synonym: 1-2,6-dimethylphenoxy propan-2-amine hydrochloride, 1-2,6-dimethylphenoxy-2-propanamine hydrochloride, 1-2,6-xylyloxy-2-aminopropane hydrochloride, 2-propanamine, 1-2,6-dimethylphenoxy-, hydrochloride, mexiletene hydrochloride, mexiletine hcl, mexiletine hydrochloride, mexitil, mexitil tn PubChem CID: 21467 ChEBI: CHEBI:6917 IUPAC Name: 1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride SMILES: CC1=C(C(=CC=C1)C)OCC(C)N.Cl

SB 431542, Tocris Bioscience™ <img src=

SB 431542, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

CHIR 99021, Tocris Bioscience™ <img src=

CHIR 99021, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 252917-06-9 Molecular Formula: C22H18Cl2N8 Molecular Weight (g/mol): 465.34 MDL Number: MFCD11846251 InChI Key: AQGNHMOJWBZFQQ-UHFFFAOYSA-N Synonym: 3-pyridinecarbonitrile, 6-2-4-2,4-dichlorophenyl-5-5-methyl-1h-imidazol-2-yl-2-pyrimidinyl amino ethyl amino, 6-2-4-2,4-dichlorophenyl-5-4-methyl-1h-imidazol-2-yl pyrimidin-2-yl amino ethyl amino nicotinonitrile, 6-2-4-2,4-dichlorophenyl-5-4-methyl-1h-imidazol-2-yl pyrimidin-2-yl amino ethyl amino pyridine-3-carbonitrile, 6-2-4-2,4-dichlorophenyl-5-4-methyl-1h-imidazol-2-yl pyrimidin-2-ylamino ethylamino pyridine-3-carbonitrile, 6-2-4-2,4-dichlorophenyl-5-5-methyl-1h-imidazol-2-yl pyrimidin-2-yl amino ethyl amino nicotinonitrile, 6-2-4-2,4-dichlorophenyl-5-5-methyl-1h-imidazol-2-yl-2-pyrimidinyl amino ethyl amino-3-pyridinecarbonitrile, chir-911, gsk-3 inhibitor xvi, unii-234cmt4gk4 PubChem CID: 9956119 IUPAC Name: 6-[(2-{[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile SMILES: CC1=CN=C(N1)C1=CN=C(NCCNC2=NC=C(C=C2)C#N)N=C1C1=C(Cl)C=C(Cl)C=C1

SR 95531 hydrobromide, Tocris Bioscience™ <img src=

SR 95531 hydrobromide, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

CAS: 104104-50-9 Molecular Formula: C15H18BrN3O3 Molecular Weight (g/mol): 368.231 InChI Key: GFZHNFOGCMEYTA-UHFFFAOYSA-N Synonym: 1 6h-pyridazinebutanoic acid, 6-imino-3-4-methoxyphenyl-, monohydrobromide, 1 6h-pyridazinebutanoicacid, 6-imino-3-4-methoxyphenyl-, hydrobromide 1:1, 4-6-imino-3-4-methoxyphenyl pyridazin-1 6h-yl butanoic acid hydrobromide, 6-amino-5-methyl-3-4-methoxyphenyl-1-pyridaziniumbutyric acid br, 6-imino-3-4-methoxyphenyl-1 6h-pyridazinebutanoic acid hydrobromide, 6-imino-3-4-methoxyphenyl-1 6h-pyridazinebutanoic acid monohydrobromide, gabazine, gabazine hydrobromide, gabazine hydrobromide,sr-95531, sr 95531 hydrobromide PubChem CID: 107895 IUPAC Name: 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid;hydrobromide SMILES: COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O.Br

Tocris Bioscience™ BDNF (human)

Tocris Bioscience™ BDNF (human)

Activates TrkB and p75 receptors

10058-F4, Tocris Bioscience™

10058-F4, Tocris Bioscience™

CAS: 403811-55-2 Molecular Formula: C12H11NOS2 Molecular Weight (g/mol): 249.346 InChI Key: SVXDHPADAXBMFB-JXMROGBWSA-N Synonym: 10058-f hplc , solid, 5-4-ethylphenyl methylene-2-thioxo-4-thiazolidinone, 5e-5-4-ethylbenzylidene-2-mercapto-1,3-thiazol-4 5h-one, 5e-5-4-ethylphenyl methylidene-2-sulfanyl-1,3-thiazol-4-one, 5e-5-4-ethylphenyl methylidene-2-sulfanylidene-1,3-thiazolidin-4-one, c-myc inhibitor, e-5-4-ethylbenzylidene-2-mercaptothiazol-4 5h-one, z,e-5-4-ethylbenzylidine-2-thioxothiazolidin-4-one PubChem CID: 1271002 IUPAC Name: (5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one SMILES: CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2

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