Advanced ImmunoChemical, Inc.

Advanced ImmunoChemical, Inc. ANTI-HUMAN INSULIN MAB

Monoclonal antibodies / Metabolic Syndrome / Monoclonal mouse anti-human insulin. MAbs:C7C9, D4B8, 7F8, 3A6, 8E2, 7F5. Hybridoma clones have been derived from hybridization of X63-Ag8-653 myeloma cells with spleen cells of Balb/c mice immunized with purified human insulin.Specificity: Insulin, human; MAb C7C9 reacts with C-terminal pentapeptide of insulin β-chain. MAbs 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. Kass for MAb 7F8 is 7.5 x 109M-1; Kass for MAb D4B8 is 1.5 x 108M-1; Kass for MAb 3A6 is 8.0 x 108M-1; Kass for MAb 8E2 is 6.0 x 108M-1; Kass for MAb C7C9 is 1.0 x 109M-1; Kass for MAb 7F5 is 1.0 x 109M-1. These antibodies cross-react with human proinsulin, bovine insulin (30%) and porcine insulin. No cross-reaction with free C-peptide. MAb isotypes: IgG1, kappa for all MAbs applications: Detection of insulin in two-site enzyme immunoassay.

Advanced ImmunoChemical, Inc. ANTI-CA-125 MAB

MONOCLONAL ANTIBODIES/Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with CA125 antigen purified from human ovarian carcinoma (MW > 1 MDa).Specificity:CA125 antigen.MAbs X52cc, X75, X325: epitope specificity group B (ISOBM classification) similar to M-11.MAb X306cc: epitope specificity group A (ISOBM classification) similar to OC125.MAb Isotypes:IgG1 for all MAbsApplications:Detection of CA125 antigen. Suggested pairs for sandwich immunoassay (capture-detection):X306cc – X52ccX306cc – X325X306cc – X75All MAbs are working in Western blotting.paraffin embedded tissue.Purification:Ion exchange chromatographyPresentation:PBS, pH 7.4, 0.09 % sodium azide (NaN3)0.15 M NaCl, 10 mM Tris, pH 7.5, 0.05% sodium azide (NaN3) for X75, X325Storage Conditions:+ 4 °C (+2°C…+8°C allowed).

Advanced ImmunoChemical, Inc. ANTI-RAT MS INSULIN PROINS MAB

Monoclonal antibodies / Metabolic Syndrome / Monoclonal mouse anti-rat-mouse insulin/proinsulin. MAbs:D6C4, D3E7Specificity:MAbs D6C4 and D3E7 directed to different antigenic determinants. Kd for MAb D6C4 is 8.1 x 10-8 M.Kd for MAb D3E7 is 6.3 x 10-8 M.MAb D6C4 and D3E7 cross-react with human, bovine and porcine insulin and proinsulin.MAb Isotypes:IgG1, kappa for MAbs D6C4 and D3E7Applications:Detection of rat-mouse insulin/proinsulin in two-site enzyme immunoassay. Recommend pair (capture-detection): D6C4 – D3E7.Antibodies D6C4 and D3E7 can be used in immunohistochemistry on frozen sections.Purification:Chromatography on protein A SepharosePresentation:PBS, pH 7.4, 0.1 % sodium azide (NaN3)Storage Conditions:+ 4 °CMaterial Safety Note:This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.

Advanced ImmunoChemical, Inc. ANTI-CANINE PARVOVIRUS MAB

MONOCLONAL ANTIBODIES/MAbs:5G7, 8H7, 2A10, 3G3, 3H6Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with canine parvovirus.Specificity:Canine parvovirusMAb Isotypes:IgG2a for MAbs 5G7, 8H7, 2A10, 3G3. IgG3 for MAb 3H6Applications:All MAbs are working in ELISA. MAbs 5G7 and 8H7 are also working in immunodiffusion, haemagglutinin inhibition and lateral flow.Recommended pairs for sandwich immunoassay (capture – detection): 5G7 – 8H7, 3G3 – 8H7, 3H6 – 8H7, 5G7 – 3H6, 3G3 – 3H6, 2A10 – 3H6, 5G7 – 2A10, 3G3 – 2A10Purification:Chromatography on protein A SepharosePresentation:PBS, pH 7.4, 0.1 % sodium azide (NaN3)Storage Conditions:+ 4 °C

Advanced ImmunoChemical, Inc. Recombinant Human Insulin-Like Growth Factor Binding Protein 5 (IGFBP-5), Source - Expressed In Mammalian Cell Line Full Length Mature Protein, Analysis:Purity > 90% (According To SDS-PAAG), Including Detected Fragments, 0.05mg

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc. Recombinant human Insulin-like growth factor binding protein 5 (IGFBP-5). Source: Expressed in mammalian cell line. Description: IGFBP-5 is expressed as full length mature protein (amino acids 21-272, UniProt ID = P24593). Applications: Suitable for use as a mass IGFBP-5 standard, standard or calibrator in immunoassay. Analysis: Purity > 90% (according to SDS-PAAG), including detected fragments. IGFBP-5 concentration is determined spectrophotometrically. Immunoreactivity is confirmed in sandwich immunoassay with specific monoclonal antibodies. Purification: Immunoaffinity purification. Presentation:40 mM sodium citrate pH 4.0Storage Conditions:-70 °C (between -65 and -80 °C allowed). Other information: Avoid repeated freezing and thawing. It is recommended to aliquot the product after the first thawing. Store the protein at pH 4.0.

Advanced ImmunoChemical, Inc. Influenza A (H1N1) Virus (Strain A/Beijing/262/95), 0.1mg

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc. Antigens/ Infectious Diseases/ Influenza A, (H1N1) virus (strain A/Beijing/262/95). Source:Allantoic fluid of 10 days old embryonated eggs, inoculated with influenza A virus, strain A/Beijing/262/95.Applications:Serological studies of influenza A virus, immunogen for antibody production.Analysis:Purity > 90 %Immunological activity:Tested with anti-influenza A monoclonal antibodies ( Cat. # 5-IVAN) in ELISA.Purification:Ultracentrifugation with 10 – 40 % sucrose gradient.Presentation:Presentation: STE, 0.09 % sodium azide (NaN3) and 0.005 % thimerosal.Inactivation:Thimerosal and beta propiolactone treatment. This product has been treated in a manner consistent with methods of inactivation. Generally accepted good laboratory practices appropriate to microbiological/viral safe handling practices and techniques are required at work.Storage Conditions:-20 °C (between -15 and -30 °C allowed).

Advanced ImmunoChemical, Inc. ANTI-ADIPONECTIN, HUMAN MAB

Monoclonal Antibodies / Metabolic Syndrome/ Adiponectin. MAbs: Adn23, Adn27, Adn36, Adn63, Adn94, Adn214, Adn222, Adn279, Adn305. Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with human recombinant adiponectin from E. coli (MAbs Adn23) or with native human Monoclonal Antibodies. Metabolic Syndrome. Monoclonal Mouse Anti-Adiponectin (MAbs Adn27, Adn36, Adn63, Adn94, Adn214, Adn222, Adn279 and Adn305). Specificity: Human serum adiponectin.

Advanced ImmunoChemical, Inc. Influenza A (H3N2) Virus (Strain A/Shangdong/9/93), 0.05mg

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc. Influenza A (H3N2) virus (strain A/Shangdong/9/93). Allantoic fluid of 10 days old embryonated eggs, inoculated with influenza A virus, strain A/Shangdong/9/93. Applications: Serological studies of influenza A virus, immunogen for antibody production. Analysis: Purity > 90 % Tested with anti-influenza A monoclonal antibodies in ELISA. Purification: Ultracentrifugation with 10 – 40 % sucrose gradient. Presentation: STE, 0.09 % sodium azide (NaN3) and 0.005 % thimerosal. Storage Conditions: -20 °C (between -15 and -30 °C allowed). Inactivation: Thimerosal and beta propiolactone treatment. This product has been treated in a manner consistent with methods of inactivation. Generally accepted good laboratory practices appropriate to microbiological/viral safe handling practices and techniques are required at work. Material Safety Note: This product is sold for research use only.

Advanced ImmunoChemical, Inc. S-100 Protein, Ββ Homodimer, Human, Source - Human Brain Tissue

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc. Antigens / Neuroscience / S-100 protein, ββ homodimer, human. Human brain tissue.Blood samples from tissue donors were tested and found to be negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis. S-100 – ββ homodimer (S100b) is suitable for use as a standard in immunoassay, as an immunogen for antiserum production and tracer for iodination. Measurements of S-100 protein in serumsamples of patients are useful in monitoring of traumatic brain injury, ischemic brain damage after circulatory arrests, in diagnosis and prognosis of clinical outcome in acute stroke. Purity > 95 %. After native gel electrophoresis by Ornstein-Davis S-100b protein is presented by one band ββ-form.S-100 protein concentration was determined by Lowry method using BSA as a standard. Lyophilized from 5 mM Tris-HCl, pH 7.5 with 5 mM 2-mercaptoethanol and 2 mM EDTA.

Advanced ImmunoChemical, Inc. CA15-3, Standard Grade, Human Milk, 250 KIU

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc. Antigens / Tumor Markers / CA15-3, standard grade. Source:Human milk.Blood sample from the donor was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.Applications:Calibrator in immunoassays, in vitro studies.Purification:High-speed centrifugation, salt precipitation and delipidization.Presentation:Solution in 1 M NaCl, 1 % Triton X 100, containing 0.09 % of sodium azide as preservative.Storage Conditions:Short-term storage (< 12 months) at +4 °C (between +2 and +8 °C allowed)Long-term storage at -20 °C (between -15 and -30 °C allowed)Material safety note:This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Advanced ImmunoChemical, Inc. CA19-9, Human Metastatic Liver Carcinoma, 250 KIU

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc. Antigens / Tumor Markers / CA19-9. Source:Human metastatic liver carcinoma.Blood sample from the tissue donor was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.Applications:Immunogen, calibrator in immunoassays, in vitro studies.Specific activity:Specific activity confirmed by enzyme immunoassay.Presentation:PBS, pH 7.4, 3 % sucrose, 0.05 % sodium azide (NaN3).Storage Conditions:-20 °C (between -15 and -30 °C allowed)Material safety note:This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.Product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Advanced ImmunoChemical, Inc. ANTI-INFLUENZA B MAB

MONOCLONAL ANTIBODIES/MAbs:R2/3Specificity:MAbs react with hemaglutinin H5 in hemagluttinin inhibition (HI) test.Applications:Indirect EIA, Western blottingPurification:Chromatography on protein A SepharosePresentation:PBS, pH 7.4, 0.1 % sodium azide (NaN3)Storage Conditions:+ 4 °C

Advanced ImmunoChemical, Inc. ANTI-CA72-4 MAB

MONOCLONAL ANTIBODIES/Monoclonal mouse anti-CA72-4. MAbs: 7C1,1C2,2C3.Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with native CA72-4. MAb isotypes: IgG1 for MAbs 7C1,1C2,2C3Applications:Detection of CA72-4 antigen. Recommended pairs for sandwich immunoassay (capture – detection):1C2 – 7C12C3 – 7C1All MAbs are working in Western blotting. Purifications: Ion exchange chromatographyPresentationPBS, pH 7.4, 0.09 % sodium azide (NaN₃)Storage Conditions:+4 °C (+2 … +8 °C allowed)

Advanced ImmunoChemical, Inc. ANTI-HUMAN HEMOGLOBIN HBA10

MONOCLONAL ANTIBODIES/MAbs:Hb4, Hb6Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with glycated (in vitro) synthetic peptide corresponding to the N-terminal end of beta-globin.Specificity:Native human HbA10MAb Isotypes:IgG1 for MAbs Hb4 and Hb6Applications:HbA1c immunoassay.Purification:MAb 4F12: Chromatography on protein A Sepharose and gel-filtration, other MAbs: Chromatography on protein A SepharosePresentation:PBS, pH 7.4, 0.1 % sodium azide (NaN3)Storage Conditions:+ 4 °C

Advanced ImmunoChemical, Inc. Anti-RABIES VIRUS MAB

MONOCLONAL ANTIBODIES/MAbs in vitro:1C5ccMAbs in vivo:4G4, New MAbs: 4F1, 7E3Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified rabies virus. Specificity:MAbs 4G4, 4F1, 7E3 are specific to glycoprotein.MAb 1C5cc has a virus-neutralizing activity in respect to the majority of standard RV and rabies-relative viruses: CVS, Lagos bat, Mokola, Flury lep, Duvenhage and the field isolates.MAb Isotypes:IgG2a for MAbs 1C5ccIgG2b for MAbs 4G4, 4F1, 7E3Applications:MAbs 1C5cc, 4G4,4F1, 7E3 are working in EIA.MAbs 4F1, 7E3 are working in Western blotting.MAbs 4F1, 7E3 are working in immunofluorescence.MAb 1C5cc works in immunocytochemistry.Purification:MAb 1C5cc is purified by chromatography on protein G Sepharose and all other MAbs on protein A Sepharose.Presentation:PBS, pH 7.4, 0.1 % sodium azide (NaN3)Storage Conditions:+ 4 °C