Imidacloprid is a potent and extensively utilized neonicotinoid pesticide employed for managing pests affecting cereals, vegetables, tea, and cotton. For research purposes, it has been shown to induce insulin resistance in cellular models.
- Reduces phosphorylation of protein kinase B (AKT) and ribosomal S6 kinase (S6K).
- High doses can impair cognitive functions in infant rats.
- Developmental exposure in zebrafish leads to neurobehavioral impairments.
- Can cause changes in antioxidant enzymes and lipid peroxidation.
- Immunotoxic effects observed at high doses in BALB/c mice.