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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Budiodarone tartrate (ATI-2042) is a chemical analogue of Amiodarone that acts as an antiarrhythmic agent. It inhibits multiple cardiac ion channels, including potassium, sodium, and calcium channels.
Acts as an antiarrhythmic agent
Inhibits multiple cardiac ion channels
Exhibits balanced potassium, sodium, and calcium channel inhibition
Chemical analogue of Amiodarone
High purity of 98.14%
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Azido-PEG3-C6-Cl is a PEG-based linker bearing an azide group used for click chemistry and PROTAC synthesis. It facilitates conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), providing a versatile building block for bioconjugation and linker design.
Contains an azide functional group for efficient CuAAC reactions.
Compatible with strain-promoted azide-alkyne cycloaddition for catalyst-free conjugation.
PEG3 spacer improves solubility and provides linker flexibility.
Terminal chlorohexyl enables further chemical modification.
High purity and characterized molecular data support synthetic use.
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2',3'-O-Isopropylideneadenosine is an adenosine analog primarily functioning as a smooth muscle vasodilator. It has also been observed to hinder cancer progression. Intended for research use only.
Acts as a smooth muscle vasodilator
Inhibits cancer progression
White to off-white solid appearance
Purity of 99.97%
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Br-PEG3-MS is a brominated, PEG-based PROTAC linker (methanesulfonate) designed for use in chemical synthesis of PROTACs and other bifunctional molecules. It provides a short PEG3 spacer with a reactive leaving group for conjugation chemistry, enabling efficient formation of linkages between ligands under standard organic conditions. For research use only.
PEG3 spacer with a terminal bromide and methanesulfonate leaving group.
Suitable for linker synthesis and nucleophilic substitution reactions.
High purity (95.0% by NMR) for reliable synthetic performance.
Low molecular weight facilitates handling in small-scale reactions.
Available in multiple small pack sizes to support medicinal chemistry workflows.
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Budiodarone tartrate (ATI-2042 tartrate) is a chemical analogue of Amiodarone that exhibits balanced inhibitory activity across multiple cardiac ion channels, specifically potassium, sodium, and calcium channels. It functions as an antiarrhythmic agent.
Chemical analogue of Amiodarone
Exhibits balanced inhibitory activity across multiple cardiac ion channels
Inhibits potassium channels
Inhibits sodium channels
Inhibits calcium channels
Functions as an antiarrhythmic agent
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Tri-GalNAc-DBCO is a synthetic ligand composed of three GalNAc units connected to DBCO. It acts as a ligand for the sialic acid-degrading protein receptor (ASGPR) and can be coupled with targeting proteins or small molecules to form GalNAc-LYTACs. Tri-GalNAc-DBCO specifically binds to ASGPR and, through receptor-mediated endocytosis, guides the coupled molecules to lysosomes for degradation.
Specifically binds to ASGPR, leading to receptor-mediated endocytosis and lysosomal degradation of coupled molecules.
Can be conjugated with various targeting proteins or small molecules to create GalNAc-LYTACs.
In vitro studies show it can be conjugated with anti-EGFR antibody, anti-HER2 antibody, and anti-PCSK9 antibody to form homogeneous conjugates capable of efficiently degrading membrane proteins.
Offered at 99.97% purity.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Purity: 99.94%
Molecular weight: 368.47
Chemical formula: C19H32N2O5
CAS number: 1841134-72-2
Appearance: Colorless to light yellow liquid
Density: 1.14±0.1 g/cm3
Used in PROTAC synthesis
Contains a BCN group for SPAAC reactions
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More