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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that contain Alkyne groups, or in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Composed of two different ligands connected by a linker
One ligand targets an E3 ubiquitin ligase
The other targets the protein of interest
Operates by harnessing the intracellular ubiquitin-proteasome system
Facilitates the selective degradation of target proteins
Intended for research use only
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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Trimethylammonium chloride (Standard) is the analytical standard of Trimethylammonium chloride This product is intended for research and analytical applications Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase[1][2]
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