Organometallic Compounds
eMolecules Chem-Impex Trimethylsilyl trifluoromethanesulfonate 5kg 213790636 24444 0 000 27607-77-8 MFCD00000406 222 250 C4H9F3O3SSi
Chem-Impex Trimethylsilyl trifluoromethanesulfonate 5kg 213790636 24444 0 000 27607-77-8 MFCD00000406 222 250 C4H9F3O3SSi
Medchemexpress LLC NH-bis(C2-PEG2-NH-Boc) | 2182601-69-8 | 250 MG
NH-bis(C2-PEG2-NH-Boc) | 2182601-69-8 | 250 MG
Apexbio Technology LLC OSI-930 728033-96-3 5mg
OSI-930 (CAS 728033-96-3) is a small molecule inhibitor targeting multiple receptor tyrosine kinases including Flt1 (IC 8 nM) KDR/VEGFR2 (IC 9 nM) CSF-1R (IC 15 nM) Lck c-Raf and Kit (IC 80 nM) In cellular studies OSI-930 inhibits proliferation and induces apoptosis in HMC-1 cells whose survival is dependent on Kit signaling while exhibiting minimal effects on COLO-205 cells under standard conditions Additionally OSI-930 inactivates cytochrome P450 3A4 in a time- and concentration-dependent manner and alters its spectral properties These characteristics make OSI-930 a valuable tool compound for investigating receptor tyrosine kinase signaling pathways and related cellular processes in cancer research
Medchemexpress LLC Tri(Amino-PEG5-amide)-amine | 2055013-52-8 | 99.9% | C45H93N7O18 | 50 MG
Tri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other to the target protein. This mechanism allows PROTACs to effectively degrade specific proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204191.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 50 MG
Aminooxy-PEG3-azide is a bifunctional PEG3 linker reagent containing an aminooxy group and an azide group, used for bioconjugation in ADC and PROTAC synthesis and for click chemistry conjugations.
- Contains an aminooxy group for oxime ligation.
- Contains an azide group for CuAAC and SPAAC click chemistry.
- Three-unit PEG spacer provides solubility and flexibility.
- High purity suitable for research applications.
- Stable when stored at -20°C in pure form.
Medchemexpress LLC Azido-PEG5-CH2CO2-NHS | 2144777-77-3 | C16H26N4O9 | 100 MG
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker designed for synthesizing PROTACs. It features an Azide group, enabling click chemistry reactions like copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Can be used in the synthesis of PROTACs
- Contains an Azide group for click chemistry reactions
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG
N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Applications in cancer-programmed cell death