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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag used for the purification of recombinant proteins. This click chemistry reagent contains an azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Multifunctional fusion tag for the purification of recombinant proteins
Contains an azide group
Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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TCO-PEG3-acid is a click chemistry reagent that contains a TCO group, which can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. It is also a click chemistry PEG linker with a terminal carboxylic acid group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators to form a stable amide bond.
Contains a TCO group for inverse electron demand Diels-Alder reaction (iEDDA)
Reacts with molecules containing Tetrazine groups
Functions as a click chemistry PEG linker
Terminal carboxylic acid group
Forms stable amide bonds with primary amine groups in the presence of activators
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N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that contain Alkyne groups, or in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Composed of two different ligands connected by a linker
One ligand targets an E3 ubiquitin ligase
The other targets the protein of interest
Operates by harnessing the intracellular ubiquitin-proteasome system
Facilitates the selective degradation of target proteins
Intended for research use only
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NH-bis(PEG3-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which are molecules designed to selectively degrade target proteins by utilizing the intracellular ubiquitin-proteasome system.
Used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets the protein of interest.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
PEG-based PROTAC linker for PROTAC synthesis
Click chemistry reagent with an azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More