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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Tos-PEG5-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting the protein intended for degradation. PROTACs leverage the intracellular ubiquitin-proteasome system for selective protein degradation.
PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Molecular weight: 476.58
Chemical formula: C22H36O9S
Appears as a viscous liquid
Colorless to light yellow
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of PROTAC SGK3 degrader-1, a potent SGK3 degrader based on PROTAC technology. This product is for research use only.
Molecular weight: 296.40
Formula: C17H28O4
Appearance: Liquid (density: 1.031 g/cm³)
Color: Colorless to light yellow
Shipping: Room temperature in continental US
Pure form storage: -20°C for 3 years, 4°C for 2 years
In solvent storage: -80°C for 6 months, -20°C for 1 month
In vitro solubility: ≥ 100 mg/mL in DMSO
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Fludrocortisone acetate is an orally active synthetic mineralocorticoid. It effectively controls sodium retention and is used in studies of cardiac injury, adrenal insufficiency, and orthostatic hypotension. Research indicates its role in managing conditions related to sodium balance and cardiovascular health.
Effectively controls sodium retention
Supports research into cardiac injury
Supports research into adrenal insufficiency
Supports research into orthostatic hypotension
Demonstrates efficacy in reducing specific enzyme activities related to cardiac injury
Shown to decrease UACR in healthy cats
Contributes to restoring quiescent morphology in choroidal endothelial cells
Assists in reducing membrane permeability in stimulated choroidal endothelial cells
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Bis-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
Intended for research use only
Not sold to patients
Viscous liquid appearance
Colorless to light yellow color
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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HO-PEG3-(CH2)6-Cl is a PEG3-based PROTAC linker containing a six-carbon chloroalkyl spacer and a terminal hydroxyl. It is supplied as a small-mass research chemical for use in chemical biology and targeted protein degradation research.
PEG3 spacer with flexible ether linkages.
Terminal hydroxyl and chloro groups for orthogonal conjugation.
Molecular formula C12H25ClO4 and molecular weight 268.78 g/mol.
Provided as a 25 mg research sample.
Intended for research use; consult product documentation for storage and purity.
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