Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Aminooxy-PEG3-azide is a bifunctional PEG-based linker bearing an aminooxy group and an azide group, suitable for conjugation chemistry. It serves as a non-cleavable three-unit PEG spacer for synthesis of antibody-drug conjugates and PROTACs, and enables click chemistry reactions such as CuAAC and SPAAC.
Used as a non-cleavable three-unit PEG linker for conjugation chemistry
Contains aminooxy and azide functional groups for orthogonal conjugation
Compatible with CuAAC and SPAAC click reactions
Molecular weight 234.25 and formula C8H18N4O4
Typical purity 95.0% (NMR)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Br-PEG3-MS is a PEG-based PROTAC linker employed in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits the ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves are agents that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
A PEG-based PROTAC linker.
Used in the synthesis of PROTACs.
Functions as a click chemistry reagent.
Contains an Azide group.
Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules.
Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing molecules.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Platycodin D may stimulate TNF-(alpha) synthesis or inhibit degradation of TNF-(alpha) mRNA. Platycodin D (10/30 uM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA). Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization. purity: 99%
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More