Organometallic Compounds
Medchemexpress LLC m-PEG3-azide | 74654-06-1 | MFCD00020141 | >98% | C7H15N3O3 | 250 MG
m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in various cycloaddition reactions.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne groups.
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Medchemexpress LLC Bis-PEG3-NHS ester | 1314378-16-9 | 97.0% | 444.39 g/mol | C18H24N2O11 | 500 MG
Bis-PEG3-NHS ester is a non-cleavable PEG-based bifunctional linker containing two N-hydroxysuccinimide (NHS) ester reactive groups used for bioconjugation and antibody-drug conjugate (ADC) construction. The three-unit PEG spacer increases hydrophilicity and solubility, while the NHS esters enable efficient coupling to primary amines on proteins and peptides.
- Non-cleavable 3-unit PEG linker for stable conjugation.
- Contains two NHS ester groups for bioconjugation to primary amines.
- Improves solubility and hydrophilicity of conjugates.
- Available in multiple package sizes, including 500 mg.
- Provided with SDS, COA, and product data sheet for quality and safety information.
Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 100 MG
NH-bis(PEG3-azide) is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 1 G
m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Useful for the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC Biotin-PEG3-SS-azide | 2866429-93-6 | 99.6% | 692.91 | C27H48N8O7S3 | 10 MG
Biotin-PEG3-SS-azide is a cleavable three-unit polyethylene glycol linker bearing a biotin group and a terminal azide, designed for conjugation chemistry in research applications. It is suitable for click chemistry reactions and as a cleavable linker in the synthesis of antibody-drug conjugates.
- Cleavable disulfide linker provides intracellular release.
- Azide functionality enables CuAAC and strain-promoted cycloaddition.
- PEG3 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable conjugation results.
- Soluble in DMSO at high concentration for in vitro use.
- Recommended storage at low temperature and protection from light to preserve stability.
Medchemexpress LLC m-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 500 MG
m-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker, where one ligand is for an E3 ubiquitin ligase and the other targets a specific protein.
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC m-PEG3-Aminooxy | 248275-10-7 | 98.0% | C7H17NO4 | 25 MG
m-PEG3-Aminooxy is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, enabling the degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Ethanamine, 2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]- | 1261350-60-0 | 95.0% | 267.79 | 25 MG
NH2-PEG3-C6-Cl is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC Azide-PEG3-Desthiobi 10mg
Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Azide-PEG3-Desthiobiotin is a click chemistry reagent it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups