Organometallic Compounds
![Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202514.png-250.jpg)
Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG
BCN-PEG3-OH is a BCN-functionalized PEG linker intended for bioconjugation and antibody-drug conjugate (ADC) synthesis. The reagent contains a bicyclo[6.1.0]nonyne (BCN) group that reacts with azides via strain-promoted alkyne-azide cycloaddition (SPAAC), enabling copper-free click chemistry in aqueous conditions.
- Non-cleavable four-unit PEG linker suitable for ADC construction.
- Enables strain-promoted alkyne-azide cycloaddition with azide-functionalized molecules.
- High reported purity for reliable conjugation performance.
- Available in multiple pack sizes, including small research quantities.
Medchemexpress LLC Ph-PEG3 100mg
Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 10 G
Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- Ligands for an E3 ubiquitin ligase and a target protein
Medchemexpress LLC THP-PEG5-OH | 146395-14-4 | 25 MG
THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also described as a reference compound.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Reference compound
Medchemexpress LLC m-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 100 MG
m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- The other ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Bis-aminooxy-PEG3 | 98627-70-4 | 98.0% | C8H20N2O5 | 50 MG
Bis-aminooxy-PEG3 (CAS: 98627-70-4) is a chemical compound with the molecular formula C8H20N2O5 and a molecular weight of 224.25. It is typically a colorless to light yellow liquid. This product is intended for research use only.
- Purity of 98.0% by NMR
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Appearance is a colorless to light yellow liquid
- Chemical structure consistent with 1H NMR and MS analysis
Medchemexpress LLC Methyl-PEG3-bromide 10g
Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl] | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202344.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl] | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 100 MG
Aminooxy-PEG3-azide is a PEG-based bifunctional linker containing an aminooxy (hydroxylamine) group and an azide group for orthogonal bioconjugation. It enables oxime formation with aldehydes or ketones and azide-alkyne click chemistry, and is supplied as a liquid at high purity for lab-scale synthesis.
- Contains aminooxy and azide functional groups for orthogonal conjugation
- Enables oxime ligation and azide-alkyne click reactions
- Suitable for ADC, PROTAC, and general bioconjugation workflows
- Supplied as a liquid with high laboratory-grade purity
- Available in small-scale pack sizes for research use
Medchemexpress LLC 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) | 2446474-09-3 | 96.6% | 50 MG
Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide based cereblon ligand and a 3-unit PEG linker, commonly used in PROTAC technology. This product is intended for research use only and has not been fully validated for medical applications.
- E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Utilizes a 3-unit PEG linker
- Used in PROTAC technology
- Targets Cereblon
Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | C28H36N8O10 | 1 MG
Folate-PEG3-C2-acid is a specialized acid fragment derived from Folate-PEG3-NHS ester, designed as a PEG-type PROTAC linker. This compound is crucial for the synthesis of PROTAC (PROteolysis TArgeting Chimera) molecules, which are heterobifunctional molecules that induce the degradation of target proteins. Its molecular structure facilitates the creation of complex PROTACs, enabling advanced research in targeted protein degradation.
- PEG-type PROTAC linker
- Acid fragment of Folate-PEG3-NHS ester
- Essential for synthesizing PROTAC molecules
- Purity of 97.56% ensures reliable experimental results
Medchemexpress LLC 14-azido-3,6,9,12-tetraoxatetradecan-1-ol | 86770-68-5 | 97.0% | 263.29 g/mol | C10H21N3O5 | 1 G
Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker with a terminal azide and a terminal alcohol, used for bioconjugation and linker installation. The azide group enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions, while the PEG5 spacer improves solubility and flexibility for conjugation workflows.
- Terminal azide enables CuAAC and SPAAC click reactions.
- PEG5 spacer increases solubility and reduces steric hindrance.
- Suitable for use as a non-cleavable linker in conjugation chemistry.
- Colorless to light yellow liquid with high purity.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 50 MG
(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand. It is used for the synthesis of PROTACs.
- Utilized for the synthesis of PROTACs
- VHL ligand
- Related to cancer targeted therapy
- Inhibitor
Medchemexpress LLC Mal-PEG5-acid | 1286755-26-7 | ≥97.0% | 25 MG
Mal-PEG5-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only.
- PEG-based PROTAC linker for chemical synthesis
- Utilizes the ubiquitin-proteasome system for selective protein degradation
- Molecular weight: 389.40
- Chemical formula: C17H27NO9
- Purity: ≥97.0%
- Appearance: Light brown to yellow liquid
- Soluble in DMSO (100 mg/mL)
Medchemexpress LLC N-(Amino-PEG5)-N-bis(PEG4-acid) | 2093152-86-2 | 99.5% | 100 MG
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative featuring an amino group and two terminal carboxylic acids. The amino group is reactive with carboxylic acids and activated NHS esters, while the terminal carboxylic acids can react with primary amine groups to form a stable amide bond. This compound is useful in the development of antibody drug conjugates (ADCs).
- Features an amino group and two terminal carboxylic acids.
- Amino group is reactive with carboxylic acids and activated NHS esters.
- Terminal carboxylic acids react with primary amine groups to form a stable amide bond.
- Useful in the development of antibody drug conjugates (ADCs).