Organometallic Compounds
Medchemexpress LLC 3,6,9,12,15-Pentaoxaheptadecane, 1,17-diazido- | 356046-26-9 | 100.0% | 332.36 | 250 MG
Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. This product is intended for research use only.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Reacts with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Reacts with molecules containing DBCO or BCN groups
Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 100 MG
NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
Medchemexpress LLC Azido-PEG3-C6-Cl | 1625717-44-3 | 95.30% | 293.79 | 25 MG
Azido-PEG3-C6-Cl is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, capable of undergoing both copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Participates in CuAAc reactions with alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups
Medchemexpress LLC O,O'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 100 MG
This product, Bis-aminooxy-PEG3, is a PEG-based PROTAC linker. It has a molecular weight of 224.25 and appears as a colorless to light yellow liquid.
- Consistent with structure based on ¹H NMR spectrum
- Consistent with structure based on MS
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 10 G
TBDMS-PEG3-OH is a polyethylene glycol (PEG) derivative used in chemical and pharmaceutical research, commonly as a linker or modifier in drug-delivery constructs and PROTAC synthesis. It is supplied as a colorless to light-yellow liquid and is typically provided at research-grade purity.
- Has a molecular weight of 264.43 g/mol.
- Chemical formula C12H28O4Si.
- CAS number 201037-95-8.
- Purity ≥98.0%.
- Supplied as a colorless to light-yellow liquid.
- Typical pack size 10 g.
- Useful as a PEG linker or modifier in drug-delivery and PROTAC synthesis.
Medchemexpress LLC N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester | 2100306-76-9 | 95.0% | C30H54N6O11S | 100 MG
N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker for the synthesis of PROTACs. It also functions as a click chemistry reagent, facilitating reactions with various alkyne-containing, DBCO, or BCN molecules.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 | C12H28O4Si | 5 G
TBDMS-PEG3-OH is a tert-butyldimethylsilyl (TBDMS)-protected triethylene glycol (PEG3) derivative used as a short PEG linker and building block in synthetic chemistry and drug-delivery research. It is a colorless to light yellow liquid (formula C12H28O4Si, MW 264.43) with high purity and defined storage conditions.
- Tert-butyldimethylsilyl-protected hydroxyl for selective deprotection.
- Short PEG3 spacer ideal for linker synthesis and conjugation.
- High purity: ≥98.0%.
- Available in bench-scale pack sizes, including 5 G.
- Stable when stored at recommended temperatures (pure: -20°C to 4°C).
Medchemexpress LLC Bis-PEG3-NHS ester | 1314378-16-9 | 97.0% | 444.39 g·mol-1 | C18H24N2O11 | 250 MG
Bis-PEG3-NHS ester is a noncleavable, three-unit polyethylene glycol (PEG) linker bearing N-hydroxysuccinimide (NHS) ester termini for amine-directed bioconjugation and antibody-agent conjugation applications.
- Provides two NHS ester termini for efficient amine coupling.
- Three-unit PEG spacer increases hydrophilicity and reduces steric hindrance.
- Noncleavable design yields stable conjugation in antibody-drug conjugate constructs.
- High purity suitable for research applications.
- Stable as a powder at -20°C for long-term storage; limited stability in solution.
![Medchemexpress LLC 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol | 1374639-77-6 | 99.0% | 251.72 | 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403746-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol | 1374639-77-6 | 99.0% | 251.72 | 10 G
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol is a drug intermediate for synthesis of various active compounds. It is intended for research use only and is not for sale to patients.
- Drug intermediate for synthesis of various active compounds.
- For research use only.