Organometallic Compounds
Medchemexpress LLC Bromoacetamido-PEG3-NH-Boc | 1421933-39-2 | ≥98.0% | C15H29BrN2O6 | 1 G
Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Utilized in the synthesis of PROTACs
- Connects ligands for E3 ubiquitin ligase and target proteins
- Enables selective degradation of target proteins
- Molecular weight: 413.30
Medchemexpress LLC 3-(2-iodoethoxy)prop-1-yne | 164118-56-3 | MFCD24459258 | 95.0% | 210.01 g·mol-1 | C5H7IO | 5 G
3-(2-Iodoethoxy)prop-1-yne is an iodo-substituted propargyl ether used as an alkyne reagent and electrophile in organic synthesis. It is employed in copper-catalyzed azide-alkyne cycloaddition (click chemistry) to introduce propargyl groups and as a handle for nucleophilic substitution, with iodine acting as a good leaving group to enable further functionalization.
- Iodo-substituted propargyl ether suitable for click chemistry.
- Acts as an electrophile; iodine is a good leaving group for substitution reactions.
- Enables introduction of alkyne functionality for bioconjugation and labeling.
- Useful in small-molecule synthesis and crosslinking applications.
- Available in laboratory-scale quantities for synthetic use.
Medchemexpress LLC Azido-PEG3-propionic acid tert-butyl ester | 252881-73-5 | MFCD22201543 | ≥98.0% | 303.35 g/mol | C13H25N3O5 | 100 MG
Azido-PEG3-propionic acid tert-butyl ester is an azide-functionalized, Boc-protected PEG3 linker for bioconjugation. It acts as a cleavable three-unit PEG spacer and an azide reagent for click chemistry, suitable for assembling antibody-drug conjugates and PROTACs.
- Azide-functionalized Boc-protected PEG3 linker.
- Cleavable three-unit PEG spacer for ADC and PROTAC synthesis.
- Suitable for CuAAC and SPAAC click chemistry.
- Purity ≥98.0%.
- Molecular weight 303.35 g/mol; formula C13H25N3O5.
- Appearance colorless to light yellow liquid; follow storage recommendations.
Medchemexpress LLC Fludrocortisone acetate | 514-36-3 | 99.6% | 1 ML
Fludrocortisone acetate is an orally active synthetic mineralocorticoid. It effectively controls sodium retention and is used in studies of cardiac injury, adrenal insufficiency, and orthostatic hypotension. Research indicates its role in managing conditions related to sodium balance and cardiovascular health.
- Effectively controls sodium retention
- Supports research into cardiac injury
- Supports research into adrenal insufficiency
- Supports research into orthostatic hypotension
- Demonstrates efficacy in reducing specific enzyme activities related to cardiac injury
- Shown to decrease UACR in healthy cats
- Contributes to restoring quiescent morphology in choroidal endothelial cells
- Assists in reducing membrane permeability in stimulated choroidal endothelial cells
Apexbio Technology LLC Ribosomal protein L3 peptide (202-222) amide 5mg
Ribosomal protein L3 peptide (202-222) amide is a synthetic peptide corresponding to residues 202 to 222 of ribosomal protein L3 with the sequence Met-Ser-His-Arg-Lys-Tyr-Glu-Ala-Pro-Arg-His-Gly-His-Leu-Gly-Phe-Leu-Pro-Arg-Lys-Arg-amide and a molecular formula of C114H182N42O25S (Mw 2573) Ribosomal protein L3 is an integral component of the large ribosomal subunit (60S) interacting with 23S rRNA to constitute the ribosome s peptidyl transferase center This particular peptide segment can bind to HIV-1 TAR RNA suggesting its role in studying TAR-mediated transcriptional activation and RNA-protein interactions in molecular virology research
Medchemexpress LLC Chloro-PEG5-chloride 1g
Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Chlorotriethylsilane | 994-30-9 | MFCD00000507 | ≥97.0% | 150.72 g/mol | C6H15ClSi | 25 G
Chlorotriethylsilane (triethylsilyl chloride) is an organosilicon reagent used in organic synthesis, commonly employed as a silylating agent and protecting group. It is supplied as a colorless to light yellow liquid with documented purity and storage recommendations for research use.
- Used as a silylating reagent and protecting group in organic synthesis.
- Supplied as a colorless to light yellow liquid; available in 25 g and larger sizes.
- Molecular formula C6H15ClSi; CAS number 994-30-9.
- Purity ≥97.0% (NMR) as verified by certificate of analysis.
- Intended for research use only; not for clinical, diagnostic, or food use.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Cayman Chemical 5 S 6 R7trihydroxymethyl Hept
A potent bioactive analog of lipoxin A4; inhibits LTB4-induced chemotaxis of PMNs (IC50 = 5 nM)
eMolecules 1-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-1H-1,2,4-TRIAZOLE | 136118-56-4 | MFCD27997533 | 1g
AstaTech | 1-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-1H-1,2,4-TRIAZOLE | 1g | 499932580 | 73093 | 95.000 | 136118-56-4 | MFCD27997533 | 199.329 | C8H17N3OSi
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eMolecules Azido-PEG3-triethoxysilane | 2243566-43-8 | | 1g
Broadpharm | Azido-PEG3-triethoxysilane | 1g | 411413991 | BP-24073 | 98.000 | 2243566-43-8 | | 450.608 | C18H38N4O7Si
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eMolecules 2-AMINO-3,3,3-TRIFLUOROPROPAN-1-OL HCL | 1196154-75-2 | MFCD10697731 | 1g
AstaTech | 2-AMINO-3,3,3-TRIFLUOROPROPAN-1-OL HCL | 1g | 323624613 | N11384 | 95.000 | 1196154-75-2 | MFCD10697731 | 165.540 | C3H7ClF3NO
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