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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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3-(2-Iodoethoxy)prop-1-yne is an iodo-substituted alkyne crosslinker used to form stable triazole linkages via copper-catalyzed azide-alkyne (CuAAC) Click Chemistry. The iodine-bearing ether enables nucleophilic substitution for further functionalization, making the compound useful for synthetic intermediates and bioconjugation workflows. It is a liquid, typically colorless to light yellow, with typical laboratory storage requirements.
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It can be used in the synthesis of the PROTAC SGK3 degrader-1, which is a potent SKG3 degrader.
Polyethylene glycol (PEG)-based PROTAC linker
Used in the synthesis of PROTAC SGK3 degrader-1
High solubility in DMSO (≥ 100 mg/mL)
Long-term stability in pure form at -20°C (3 years) and 4°C (2 years)
Extended stability in solvent at -80°C (6 months) and -20°C (1 month)
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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Mangafodipir trisodium (MnDPDP) is a hepatocellular-specific contrast agent and an efficacious inhibitor of chemotherapy-induced peripheral neuropathy (CIPN) and other conditions caused by cellular oxidative stress. It does not negatively interfere with the tumoricidal activity of chemotherapy.
Inhibits effect of HGrC cell viability caused by H2O2
Attenuates apoptosis caused by cisplatin in HGrC cells
Shows protective effects against ovarian damage caused by cisplatin and paclitaxel in mice
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL E3 ligase ligand-linker conjugate used as a building block in the synthesis of PROTACs and other conjugates. It features a PEG3 spacer and a bicyclononyne (BCN) functional group to facilitate bioorthogonal conjugation and assembly of bifunctional molecules for targeted protein degradation research.
VHL E3 ligase ligand for targeted protein degradation applications.
PEG3 linker provides a flexible spacer for molecular conjugation.
BCN functional group enables strain-promoted bioorthogonal click conjugation.
Reported high purity suitable for synthetic chemistry use.
Intended as a small-molecule building block for PROTAC assembly and conjugation workflows.
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