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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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This compound serves as a PEG-based linker for assembling Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed with two distinct ligands connected by such a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This design enables PROTACs to leverage the cell's ubiquitin-proteasome system for the targeted degradation of proteins.
Functions as a linker for PROTACs.
Utilizes the ubiquitin-proteasome system.
Enables targeted protein degradation.
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Enozertinib hemihydrate is a small-molecule, brain-penetrant inhibitor of EGFR and HER2 supplied as a hemihydrate for research use. It is orally bioavailable and exhibits antineoplastic activity against EGFR-altered tumors, including exon 20 insertions; intended for laboratory research and not for human use.
Hemihydrate form for consistent handling and stability.
High purity suitable for biochemical and cellular assays.
Brain-penetrant and orally bioavailable properties.
Targets EGFR and HER2 alterations, including exon 20 insertions.
Supplied in small-mass packs for preclinical research.
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Applications in cancer-programmed cell death
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More