Organometallic Compounds
Medchemexpress LLC S -2- 2- tert-Buto 5g
(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds
Medchemexpress LLC Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate | 252881-73-5 | 303.3547 g/mol | C13H25N3O5 | 50 MG
N3-PEG3-CH2CH2-Boc is an azido-terminated PEG3 linker with a tert-butyl (Boc) protected carboxylic acid end, used as a cleavable PEG-based linker in antibody-drug conjugate and PROTAC synthesis, and as an azide reagent for click chemistry.
- Azide-terminated PEG3 linker suitable for click chemistry.
- tert-Butyl (Boc) protected carboxyl end for orthogonal deprotection.
- Used in ADC and PROTAC linker assembly.
- Available as a small pre-weighed laboratory pack for synthetic use.
Medchemexpress LLC 14-azido-3,6,9,12-tetraoxatetradecan-1-ol | 86770-68-5 | 97.0% | 263.29 g/mol | C10H21N3O5 | 1 G
Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker with a terminal azide and a terminal alcohol, used for bioconjugation and linker installation. The azide group enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions, while the PEG5 spacer improves solubility and flexibility for conjugation workflows.
- Terminal azide enables CuAAC and SPAAC click reactions.
- PEG5 spacer increases solubility and reduces steric hindrance.
- Suitable for use as a non-cleavable linker in conjugation chemistry.
- Colorless to light yellow liquid with high purity.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 369.45 g/mol | C19H31NO6 | 100 MG
BCN-PEG3-OH is a BCN-functionalized PEG linker used for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and bioconjugation applications such as antibody-drug conjugate assembly. It provides a short PEG spacer with a reactive bicyclononyne moiety to enable site-selective conjugation without metal catalysts.
- Bcn functional group enables copper-free SPAAC click chemistry.
- Three-unit PEG spacer provides flexibility and solubility for conjugates.
- Suitable for antibody-drug conjugate synthesis and site-specific bioconjugation.
- Reactive alcohol terminus allows further functionalization or coupling reactions.
- Compact molecular weight and defined formula support precise stoichiometry in conjugation workflows.
Medchemexpress LLC Bis-aminooxy-PEG3 | 98627-70-4 | 98.0% | C8H20N2O5 | 50 MG
Bis-aminooxy-PEG3 (CAS: 98627-70-4) is a chemical compound with the molecular formula C8H20N2O5 and a molecular weight of 224.25. It is typically a colorless to light yellow liquid. This product is intended for research use only.
- Purity of 98.0% by NMR
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Appearance is a colorless to light yellow liquid
- Chemical structure consistent with 1H NMR and MS analysis
Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 100 MG
Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and alkyl/ether-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Bromoacetamido-PEG3-C2-Boc | 1807537-33-2 | C15H28BrNO6 | 500 MG
Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are molecules that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g·mol⁻¹ | C10H21N3O5 | 5 G
Azido-PEG5-alcohol is an azide-terminated polyethylene glycol linker containing five ethylene glycol units and a terminal primary alcohol, used as a water-soluble reagent for bioconjugation and linker synthesis. It is commonly applied in click chemistry and in the construction of antibody-drug conjugates and PROTACs.
- Azide functionality enables CuAAC and SPAAC click reactions.
- Water-soluble PEG5 spacer improves solubility and flexibility.
- Terminal primary alcohol provides a synthetic handle for derivatization.
- Suitable for ADC linker synthesis and PROTAC construction.
- Supplied as a solid with reported purity >97.0%.
Medchemexpress LLC EGGGG-PEG8-amide-bis(deoxyglucitol) | 2842855-38-1 | 98.9% | C49H91N9O28 | 50 MG
EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker used for research purposes. It is a solid-liquid mixture, white to off-white in color, with a molecular weight of 1254.29.
- Cleavable ADC linker
- Solid-liquid mixture
- White to off-white color
- For research use only
Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | MFCD23726612 | 98.0% | 335.35 g/mol | C13H25N3O7 | 500 MG
Azido-PEG5-acid is an azide-terminated, five-unit polyethylene glycol linker with a terminal carboxylic acid that enables click-chemistry bioconjugation reactions. It is used as a PROTAC and ADC linker and is compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted cycloaddition reactions.
- Azide functional group for CuAAC and SPAAC reactions.
- Five-unit PEG spacer provides water solubility and flexibility.
- Terminal carboxylic acid enables amide or ester coupling.
- Typical purity ≥98.0%.
- Suitable for linker synthesis and bioconjugation applications.
Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | MFCD23726612 | ≥98.0% | 335.35 | C13H25N3O7 | 1 G
Azido-PEG5-acid is a PEG-based, azide-terminated 5-unit linker used for bioconjugation and click chemistry. It is water soluble and commonly used as a linker in PROTAC and ADC synthesis, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC).
- Azide functional group for CuAAC and SPAAC
- Five-unit PEG spacer provides water solubility
- Molecular weight 335.35 g/mol
- CAS number 1425973-16-5
- Purity ≥98.0%
- Appearance: colorless to light yellow liquid
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)