Selleck Chemical LLC GA-017-E1145-5MG
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively