Steroids and derivatives
Medchemexpress LLC 3-epi-Vitamin D3 (Epicholecalciferol) | 57651-82-8 | C27H44O | 100 MG
3-epi-Vitamin D3 (Epicholecalciferol) is a Vitamin D3 analogue that acts as a Hedgehog pathway inhibitor. It has demonstrated antiproliferative activity in human U87MG cells with an IC50 of 39.2 μM. This compound is intended for research use only.
- Hedgehog pathway inhibitor
- Exhibits antiproliferative activity against U87MG cells
- Significantly upregulates Cyp24A1 in various cell lines
Medchemexpress LLC Vitamin D2 (ergocalciferol) | 50-14-6 | 99.1% | C28H44O | 10 G
Vitamin D2 (Ergocalciferol) is derived from plant sources or dietary supplements and can be used as a supplement of Vitamin D. This product is intended for research use only.
- Derived from plant sources
- Can be used as a supplement of vitamin D
- For research use only
- Molecular weight: 396.65
- Appearance: solid
- Color: white to light yellow
- Structure classification: steroids
- Initial source: plants other families
- Endogenous metabolite: human gut microbiota metabolites
- Shipping at room temperature in continental US
- Store at -20°C, protected from light, under nitrogen
- Unstable in solutions; freshly prepared is recommended
- Solubility (in vitro): DMSO: 31.25 mg/mL (78.78 mM)
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eMolecules 1027801-74-6 | MHAPC-Chol | Broadpharm544.865 | C34H60N2O3 | 0.000 | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)CCO | 1mg | 779524211
MHAPC-Chol | Broadpharm | 1027801-74-6544.865 | C34H60N2O3 | 0.000 | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)CCO | 1mg | 779524211
eMolecules 7575-93-1 | Methyl-d3 4-Methylbenzenesulfonate | Accela ChemBio (ASD) | MFCD00008417 | 186.230 | C8H10O3S | 98.000 | COS(=O)(=O)c1ccc(C)cc1 | 1g | 536764358
Methyl-d3 4-Methylbenzenesulfonate | Accela ChemBio (ASD) | 7575-93-1 | MFCD00008417 | 186.230 | C8H10O3S | 98.000 | COS(=O)(=O)c1ccc(C)cc1 | 1g | 536764358
Medchemexpress LLC N-Butyrylglycine-d2 | 1219799-10-6 | 99.17% | 147.17 | 10 MG
N-Butyrylglycine-d2 is the deuterium labeled N-Butyrylglycine. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. This compound is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Spaglumic acid-d3 | 94.9% | 307.27 g/mol | C11H13D3N2O8 | 1mg
Spaglumic acid-d3 (N-Acetylaspartylglutamic acid-d3) is the deuterium labeled Spaglumic Acid (HY-100921) Spaglumic Acid is a neuropeptide[1]
Medchemexpress LLC 7-Methylguanosine-d3 | 20244-86-4 | 98.5% | 301.29 | 1 MG
7-Methylguanosine-d3 is a deuterium-labeled variant of 7-Methylguanosine, which functions as a cNIIIB nucleotidase inhibitor with an IC50 value of 87.8 ± 7.5 μM. Deuterium-labeled compounds are frequently used in drug development as tracers for quantitative analysis, and deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Can be an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
- Deuterium substitution may affect pharmacokinetic and metabolic profiles.
Cambridge Isotope Laboratories 24R,25-DIHYDROXYVITAMIN D2 UNLABELED 100 UG/ML IN ETHANOL, 1 ML
24R,25-DIHYDROXYVITAMIN D2 UNLABELED 100 UG/ML IN ETHANOL, 1 ML
Medchemexpress LLC Herniarin-d3 (7-Methoxycoumarin-d3) | 1600535-74-7 | 179.19 | 1 MG
Herniarin-d3 is the deuterium labeled version of Herniarin, a natural coumarin found in some flowering plants known for its anticancer effects. It significantly decreases cell viability by inducing apoptosis in MCF-7 cells and also exhibits anti-dermatophytic activity. It can be used in the study of bladder cancer and breast cancer. Deuteration, the incorporation of stable heavy isotopes of hydrogen, is used in drug molecules largely as tracers for quantitation during drug development and has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potentially affects the pharmacokinetic and metabolic profiles of drugs
BIOHIPPO AAV-D2-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing EGFP under the D2 promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3β,5E,7E,22E)- (9CI) | 51744-66-2 | 97.0% | C28H44O | 25 MG
5,6-trans-Vitamin D2 is an odorless white crystalline or powder form of vitamin D. It is soluble in alcohol, chloroform, ether, and fatty oils, but degrades with exposure to air, light, and acidic conditions. Its biological role involves promoting calcium and phosphate absorption in the small intestine, enhancing their release from bones, and reducing their renal excretion.
- Used as a dietary supplement and food additive.
- Helps prevent milk fever in cows and combats atrophic rhinitis in pigs.
- Assists in fracture repair for felines and canines.
- Addresses hypocalcemia, hypophosphatemia, rickets, osteomalacia, and renal osteodystrophy.
- Supports osteoporosis treatment when combined with calcium.
Medchemexpress LLC 5,6-trans-vitamin D2 | 51744-66-2 | 97.0% | C28H44O | 50 MG
5,6-trans-Vitamin D2 is an isomer of Vitamin D2. It is for research use only. This product is an off-white to light yellow solid.
- Isomer of Vitamin D2
- Off-white to light yellow solid
- For research use only
- Solubility in DMSO: 25 mg/mL (63.03 mM)
- Recommended storage for solid: -20°C, protect from light, stored under nitrogen
- Recommended storage in solvent: -80°C for 6 months, or -20°C for 1 month (protect from light, stored under nitrogen)
Medchemexpress LLC Alosetron-d3 hydrochloride | 1189919-71-8 | 99.0% | C17H16D3ClN4O | 5 MG
Alosetron-d3 hydrochloride is a deuterium labeled Alosetron, functioning as a serotonin 5HT3-receptor antagonist. It is suitable for use as a tracer and an internal standard in NMR, GC-MS, or LC-MS analysis for quantitative applications.
- Deuterium labeled compound
- Serotonin 5HT3-receptor antagonist
- Internal standard for quantitative analysis
- Used in neurological disease research
- Supports drug concentration detection
Medchemexpress LLC 1α,25-dihydroxy-3-epi-vitamin D3 | 61476-45-7 | MFCD28963706 | 98.5% | 416.64 g·mol⁻1 | C27H44O3 | 5 MG
1S-Calcitriol is a stereoisomer of calcitriol (1α,25-dihydroxyvitamin D3) that functions as a potent vitamin D receptor (VDR) agonist. It is provided as a high-purity solid research reagent for use in cellular, biochemical, and pharmacological studies of VDR signaling, calcium homeostasis, and related physiological processes.
- Potent vitamin D receptor agonist.
- Useful for studying keratinocyte proliferation and differentiation.
- Supports investigation of parathyroid hormone regulation and calcium signaling.
- Provided as a high-purity solid for analytical and biological assays.
- Chemical formula C27H44O3; molecular weight 416.64 g·mol⁻1.