Steroids and derivatives
Aobchem 2-Methoxy-5-nitrophenyl acetate | ≥97% | CAS 53606-41-0 | C9H9NO5 | 25g
2-Methoxy-5-nitrophenyl acetate | ≥97% | CAS 53606-41-0 | C9H9NO5 | 25g
Medchemexpress LLC Digitonin | 11024-24-1 | 500 MG
Digitonin is a glycoside derived from Digitalis purpurea. Functioning as a natural detergent, it can enhance cell permeability by binding to cholesterol molecules and has shown potential to reduce tumor growth. This product is for research use only.
- Obtained from Digitalis purpurea
- Increases cell permeability by binding to cholesterol molecules
- May reduce tumor growth
- Natural detergent properties
- Purity of 54.4%
- Solid appearance, off-white to light yellow color
- Store at 4°C, under nitrogen for solid form
- Soluble in water at 100 mg/mL (requires ultrasonic)
Medchemexpress LLC Digitonin | 11024-24-1 | 1 G
Digitonin is a glycoside obtained from Digitalis purpurea. It is a natural detergent that increases cell permeability by binding to cholesterol molecules, and has been shown to reduce tumor growth. In vitro, Digitonin enhances cell permeability by interacting with cholesterol in cell membranes, leading to increased cisplatin accumulation and reduced tumor growth. In vivo studies indicate that Digitonin, when administered intra-arterially at 5 mg/kg, enhances the tumor-growth retarding effect of carboplatin without altering liver parenchyma blood flow.
- Molecular formula: C56H92O29
- Molecular weight: 1229.31
- Target: Others
- Pathway: Others
- Storage: 4°C, stored under nitrogen
- In solvent storage: -80°C for 6 months; -20°C for 1 month (stored under nitrogen)
- Solubility in H2O: 100 mg/mL (81.35 mM); requires ultrasonic treatment
Medchemexpress LLC Petrelintide acetate | 99.8% | 4191.69 (free base) | 1 MG
Petrelintide acetate is a dual amylin and calcitonin receptor agonist (DACRA). It elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, leading to a loss of fat mass while preserving lean mass during weight reduction. It can be used in diabetes research.
- Dual amylin and calcitonin receptor agonist (DACRA)
- Selectively reduces high-fat diet intake
- Promotes fat mass loss while preserving lean mass
- Potential application in diabetes research
Medchemexpress LLC 17β-Estradiol sulfate sodium | 4999-79-5 | 99.0% | C18H23NaO5S | 25 MG
17β-Estradiol sulfate sodium, also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid used for research applications. This compound is supplied as a white to light yellow solid with a high purity of 99.0%.
- Neuroactive steroid
- High purity of 99.0%
- Supplied as a white to light yellow solid
- Suitable for research applications
- Store product at 4°C, sealed, and away from moisture
- Store stock solutions at -80°C for up to 6 months, or -20°C for up to 1 month
- Highly soluble in DMSO
![eMolecules 206986-87-0 | Sodium cholate hydrate | Oakwood Chemical | MFCD00150749 | 448.576 | C24H41NaO6 | 95.000 | O.[Na+].C[C@H](CCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C | 1g | 537719715](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502141943.JPG-250.jpg)
eMolecules 206986-87-0 | Sodium cholate hydrate | Oakwood Chemical | MFCD00150749 | 448.576 | C24H41NaO6 | 95.000 | O.[Na+].C[C@H](CCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C | 1g | 537719715
Sodium cholate hydrate | Oakwood Chemical | 206986-87-0 | MFCD00150749 | 448.576 | C24H41NaO6 | 95.000 | O.[Na+].C[C@H](CCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C | 1g | 537719715
Medchemexpress LLC Dexamethasone phosphate disodium | 2392-39-4 | 99.94% | 516.40 | 500 MG
Dexamethasone phosphate disodium is an orally active Glucocorticoid receptor agonist. It regulates various transcription factors, including activator protein-1, nuclear factor-AT, and nuclear factor-kB, to influence inflammatory response genes.
- Potently inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) release from A549 cells
- Induces transcription of the β2-receptor
- Inhibits 3xκB (NF-κB, IκBα, and I-κBβ) activity
- Efficiently inhibits lipopolysaccharide (LPS)-induced inflammation in vivo
- Decreases recruitment of granulocytes and spontaneous production of oxygen radicals in vivo
Medchemexpress LLC 1-Methyladenosine-d3 hydriodide | 15763-06-1 | 98.8% | 412.20 | 1 MG
1-Methyladenosine-d3 hydriodide is a deuterium-labeled version of 1-Methyladenosine. This RNA modification serves as a tumor marker, with elevated levels linked to cancer development. Its methylation leads to the upregulation of PPARδ expression, regulating cholesterol metabolism and activating the Hedgehog signaling pathway, contributing to liver tumorigenesis. This compound is intended for research use only and can be used as a tracer and internal standard for quantitative analysis.
- Deuterium-labeled version of 1-Methyladenosine
- Functions as a tumor marker
- Upregulates PPARδ expression
- Regulates cholesterol metabolism
- Activates Hedgehog signaling pathway
- Contributes to liver tumorigenesis
- Suitable as a tracer for quantitative analysis
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical 1-hydroxy VItamIn D3 1mg
A synthetic prodrug which is converted to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo; suppresses the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; supports bone growth; provides renal and cardiovascular protection during chronic kidney disease
Cayman Chemical 1-hydroxy VItamIn D3 10mg
A synthetic prodrug which is converted to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo; suppresses the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; supports bone growth; provides renal and cardiovascular protection during chronic kidney disease
Cayman Chemical 1-hydroxy VItamIn D2 10mg
A synthetic prodrug of 1,25-dihydroxy vitamin D2; used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; stimulates bone growth; inhibits the growth of certain blastomas and prostate cancer cells
Sigma Aldrich Fine Chemicals Biosciences Estriol 16alpha beta D glu10MG
Estriol 16alpha beta D glu10MG
Cayman Chemical Dexamethasone Phosphate sodi
A glucocorticoid; reduces LPS-induced production of RANTES, TGF-β1, and NO in BV-2 microglia from 1-4 µM; reverses LPS-induced decreases in IL-10 levels in, and inhibits LPS-induced migration of, BV-2 microglia at 4 µM; decreases motor activity and reduces adrenal weight and plasma corticosterone levels in rats when administered in the drinking water at 5 UG/ml; reduces joint swelling in a rat model of collagen-induced arthritis at 1.6 mg/kg per day for a minimum of seven days; reduces pruritis and the clinical lesion score in cats with hypersensitivity dermatitis