Steroids and derivatives
Medchemexpress LLC Ciraparantag acetate | 1644388-83-9 | 98.0% | 10 MG
Ciraparantag acetate is a small-molecule, broad-spectrum reversal agent supplied as the acetate salt for research and preclinical use. It neutralizes a range of anticoagulants including low-molecular-weight heparins, unfractionated heparin, and certain direct oral anticoagulants; it is not indicated for vitamin K antagonists. For laboratory research only.
- Broad-spectrum reversal activity against multiple anticoagulant classes.
- Provided as an acetate salt suitable for research applications.
- High purity: 98.0%.
- Available in multiple pack sizes, including 10 mg.
- Molecular weight approximately 512.70 g/mol (free base reported).
- CAS number 1644388-83-9 for substance identification.
Medchemexpress LLC ACTH (11-24) acetate | 99.88% | 1652.04 (free base) | 5 MG
ACTH (11-24) (acetate) is an adrenocorticotropic hormone (ACTH) receptor antagonist. It is a fragment of adrenocorticotropic hormone and induces cortisol release. This product can be used for research of the central nervous system.
- Elicits cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells.
- Has slight influences on circulating plasma corticosterone values and on fighting behavior.
Medchemexpress LLC Ciraparantag acetate | 1644388-83-9 | 98.0% | 873.01 | 5 MG
Ciraparantag acetate (PER977) is a thrombin and factor Xa inhibitor that functions as a broad-spectrum reversal agent for anticoagulants, including low molecular weight heparins, unfractionated heparins, and some direct oral anticoagulants. It does not reverse Vitamin K antagonists (VKAs).
- Small, synthetic, and cationic molecule
- Binds to direct Factor Xa inhibitors and direct thrombin inhibitors
- Binds to unfractionated and low molecular weight heparin (LMWH) through non-covalent hydrogen bonds and charge-charge interactions
- Shows reversal of anticoagulants in rat-tail transection bleeding assays
- Reduces bleeding as observed in thromboelastography studies
- Soluble in H2O at 125 mg/mL (requires ultrasonic treatment)
Medchemexpress LLC Norethisterone enanthate | 3836-23-5 | 99.19% | C27H38O3 | 250 MG
Norethisterone enanthate is a long-acting parenteral progestogen, orally active, and functions as a click chemistry reagent. It contains an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This compound is intended for research use only.
- Long-acting parenteral progestogen
- Orally active
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Can be used as an intramuscular contraceptive agent in vitro
- Inhibits fertility in female rats in vivo
- White to off-white solid appearance
- Soluble in DMSO (200 mg/mL)
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 25 MG
Bazedoxifene acetate is an oral, nonsteroidal selective estrogen receptor modulator (SERM) that acts as an inhibitor of IL-6/GP130 protein-protein interactions. It is used in research for osteoporosis and pancreatic cancer.
- Small molecular GP130 inhibitor
- Inhibits STAT3 phosphorylation induced by IL-6 and IL-11
- Induces apoptosis in human pancreatic cancer cells
- Inhibits STAT3 nuclear translocation induced by IL-6
- Blocks cell migration in pancreatic cancer cells by inhibiting GP130
- Inhibits Capan-1 tumor growth in mouse models
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 99.5% | 1006.63 | 10 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits high affinity for both human (hV2R) and rat (rV2R) V2 receptors, with EC50s of 0.07 nM and 0.02 nM respectively. This product is intended for research purposes only.
- Potent and selective V2 receptor agonist
- Short-acting peptidic compound
- High affinity for human and rat V2 receptors
- For research purposes only
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 1006.64 g/mol | 1 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits EC50 values of 0.07 nM for human V2R (hV2R) and 0.02 nM for rat V2R (rV2R). This product is stable under recommended storage conditions and is not classified as a hazardous substance or mixture according to safety data.
- Potent, selective, and short-acting peptidic V2 receptor (V2R) agonist
- EC50 values of 0.07 nM for human V2R (hV2R)
- EC50 values of 0.02 nM for rat V2R (rV2R)
- Stable under recommended storage conditions
- Not a hazardous substance or mixture
- For research use only