Drug Standards
Apexbio Technology LLC Amitriptyline HCl 549-18-8 1g
Amitriptyline HCl (CAS 549-18-8) is a tricyclic compound that modulates multiple neurotransmitter systems It acts as an inhibitor at serotonin and norepinephrine receptors demonstrating potent activity with IC50 values of 3 45 nM and 13 3 nM respectively Amitriptyline also exhibits notable affinity for 5-HT4 (IC50 7 31 nM) 5-HT2 (IC50 235 nM) and sigma-1 receptors (IC50 287 nM) indicating a broad spectrum of receptor interactions This pharmacological profile supports its application in neuropharmacological research including studies of synaptic transmission antidepressant mechanisms and receptor signaling pathways
Cayman Chemical Fenofibrate Other Receptor Mod
A PPARα agonist (EC50s = 18 and 30 μM for mouse and human receptors, respectively, in a transactivation assay); selective for PPARα over PPARγ (EC50s = 300 and 200 μM for mouse and human receptors, respectively) and lacks activity at mouse and human PPARδ at 100 μM; reduces plasma levels of triglycerides, C-reactive protein, and MDA in mice with fructose-induced hypertriglycemia from 50-100 mg/kg; decreases cisplatin-induced glomerular and tubular atrophy and necrosis in rat kidney at 100 mg/kg; reduces the number of 4-NQO-induced pulmonary lesions in lung in TSOD mice
Medchemexpress LLC Tofacitinib impurity 3 | 1616761-00-2 | 99.84% | C₁₆H₁₉ClN₆O | 5 MG
Tofacitinib impurity 3 is an impurity of Tofacitinib, primarily used as a laboratory chemical and for the manufacture of substances.
- Suitable for laboratory use.
- Used in the manufacture of substances.
- Store sealed at 4°C, away from moisture.
- Stable in solvent at -80°C for 6 months, or -20°C for 1 month.
- Can be shipped at room temperature if less than 2 weeks.
eMolecules 9-Amino minocycline, HCl | 149934-21-4 | MFCD00919549 | 1g
Combi-Blocks | 9-Amino minocycline, HCl | 1g | 457921202 | QA-2490 | 95.000 | 149934-21-4 | MFCD00919549 | 508.960 | C23H29ClN4O7
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eMolecules Building Block Tool
Medchemexpress LLC Nevirapine | 129618-40-2 | MFCD00866928 | 99.9% | 266.30 g/mol | C15H14N4O | 1 ML
Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase supplied as a research reagent in a 10 mM solution (1 mL). It is intended for use in antiviral research, assay development, and analytical applications where a characterized NNRTI standard is required.
- Non-nucleoside reverse transcriptase inhibitor for HIV-1 research.
- Concentration: 10 mM in 1 mL solution.
- High purity: 99.9% assay.
- Chemical formula C15H14N4O; molecular weight 266.30 g/mol.
- Soluble in DMSO (≈53.66 mM) and compatible with common in vivo vehicles; refer to datasheet for preparation.
- Recommended storage conditions for powder and in-solution formats are provided on the product datasheet.
Apexbio Technology LLC Oxfendazole 53716-50-0 50mg
Oxfendazole (CAS 53716-50-0) is a small-molecule inhibitor targeting parasite tubulin It is designed to inhibit microtubule polymerization thereby disrupting microtubule function and promoting parasite elimination Oxfendazole exerts its biological activity primarily through binding to tubulin and inhibiting parasite microtubule polymerization In in vitro studies Oxfendazole demonstrates antiparasitic and antitumor activity with IC50 values typically ranging from low micromolar to submicromolar levels depending on the specific cell lines and experimental settings Based on these pharmacological properties Oxfendazole holds research potential in the investigation of antiparasitic activity tumor cell growth inhibition and mechanistic studies of microtubule destabilization
Sigma Aldrich Fine Chemicals Biosciences Benserazide impurity C European Pharmacopoeia (EP) Reference Standard | 787504-88-5 |
Benserazide impurity C European Pharmacopoeia (EP) Reference Standard | Mol Wt: 255.23 | 787504-88-5 |
Sigma Aldrich Fine Chemicals Biosciences Acamprosate calcium United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2) | 77337-73-6 | 200MG
Acamprosate calcium United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2) | Mol Wt: 200.24 | 77337-73-6 | 200MG
Medchemexpress LLC Lenalidomide-5-Br | 1010100-26-1 | 99.9% | 323.15 g·mol⁻¹ | C13H11BrN2O3 | 1 G
Lenalidomide-5-Br is a lenalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ubiquitin ligase for chemical biology applications. It is supplied as a research-grade building block for PROTAC design, where it can be conjugated to a protein-targeting ligand via a linker.
- Lenalidomide-derived CRBN ligand for recruitment of cereblon
- Suitable for PROTAC design and linker conjugation
- High purity appropriate for research use
- Available in multiple pack sizes (1 g-100 g)
- Molecular formula C13H11BrN2O3, molecular weight 323.15 g·mol⁻¹
Medchemexpress LLC Ticagrelor impurity 6 | 2216753-87-4 | 99.1% | C23H28F2N6O4S | 1 MG
Ticagrelor impurity 6 is a high-purity chemical compound, presenting as a white to off-white solid. It has a molecular weight of 522.57 and a chemical formula of C23H28F2N6O4S. This substance serves as an impurity of Ticagrelor.
- Impurity of ticagrelor
- High purity (99.12%) for research applications
- White to off-white solid appearance
- Suitable for laboratory chemical uses
- Identified as a drug intermediate