Drug Standards
Medchemexpress LLC Decitabine | 2353-33-5 | 99.9% | C8H12N4O4 | 2 G
Decitabine is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. It incorporates into DNA in place of cytosine, which can covalently trap DNA methyltransferase to DNA, leading to irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis, demonstrating potent anticancer activity.
- Deoxycytidine analogue antimetabolite
- DNA methyltransferase inhibitor
- Induces cell G2/M arrest
- Induces cell apoptosis
- Exhibits potent anticancer activity
Medchemexpress LLC Abemaciclib Impurity 1 | 1231930-33-8 | C11H12BrFN2 | 50 G
Abemaciclib Impurity 1 (6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole) is a drug intermediate for the synthesis of various active compounds.
- Keep container tightly sealed in a cool, well-ventilated area
- Keep away from direct sunlight and sources of ignition
- Recommended storage temperature for powder: -20°C for 3 years or 4°C for 2 years
- Recommended storage temperature in solvent: -80°C for 6 months or -20°C for 1 month
- Shipping at room temperature if less than 2 weeks
Medchemexpress LLC Decitabine (Standard) | 2353-33-5 | 99.9% | C8H12N4O4 | 5 MG
Decitabine (Standard) is the analytical standard of Decitabine, intended for research and analytical applications. It is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. It incorporates into DNA in place of cytosine, covalently trapping DNA methyltransferase and causing irreversible enzyme inhibition, leading to cell G2/M arrest and apoptosis. This compound demonstrates potent anticancer activity.
- Analytical standard for Decitabine
- Intended for research and analytical applications
- Orally active deoxycytidine analogue antimetabolite
- DNA methyltransferase inhibitor
- Induces cell G2/M arrest and apoptosis
- Demonstrates potent anticancer activity
- Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC N-acetyl mesalazine | 51-59-2 | 99.9% | C9H9NO4 | 1 ML
N-acetyl mesalazine is the primary intestinal metabolite of 5-aminosalicylic acid and acts as a biomarker for its efficacy. It can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. This compound is suitable for research into conditions such as colitis and colon cancer.
- Primary intestinal metabolite of 5-aminosalicylic acid
- Serves as a biomarker for 5-aminosalicylic acid efficacy
- Scavenges free radicals
- Reduces DNA base hydroxylation
- Ameliorates mucosal inflammation
- Suitable for research into colitis and colon cancer
- Inhibits •OH radical-stimulated DNA base hydroxylation in calf thymus DNA
Medchemexpress LLC Tolterodine impurity 1 | 260389-90-0 | C22H31NO2 | 500 MG
Tolterodine impurity 1 is an impurity of Tolterodine (HY-A0024).
- Impurity of tolterodine
Apexbio Technology LLC Fexofenadine HCl 153439-40-8 50mg
Fexofenadine HCl (CAS 153439-40-8) is a non-sedating antihistamine that selectively antagonizes the histamine H1 receptor It inhibits H1 receptor-mediated signaling with an IC50 of 246 nM indicating potent receptor binding in vitro Fexofenadine is employed in biomedical research to investigate histaminergic pathways allergic responses and receptor pharmacology facilitating the study of H1 receptor antagonism in cellular and molecular models
eMolecules 676129-92-3 | Medchem Express | Devaleryl Valsartan Impurity | 5mg | 602878385 | HY-131280 | MFCD30342453 | 351.41 | C19H21N5O2
Medchem Express | Devaleryl Valsartan Impurity | 5mg | 602878385 | HY-131280 | 676129-92-3 | MFCD30342453 | 351.410 | C19H21N5O2
eMolecules 518-28-5 | Medchem Express | Podofilox | 100mg | 446265946 | HY-15552 | MFCD00075290 | 414.41 | C22H22O8
Medchem Express | Podofilox | 100mg | 446265946 | HY-15552 | 518-28-5 | MFCD00075290 | 414.410 | C22H22O8
TARGETMOL CHEMICALS INC ARQ 531 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity, with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. Purity 99.59%
Cayman Chemical OxIbendazole 25mg
A benzimidazole anthelmintic; inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM, respectively); reduces fecal worm egg counts in dogs and cats by greater than 90% for the nematodes T. canis, T. vulpis, A. caninum, and T. leonine at 15 mg/kg in combination with niclosamide; reduces fecal egg counts of strongyles in horses at 10 mg/kg per day
eMolecules 107910-75-8 | Medchem Express | Ganciclovir (sodium) | 100mg | 533802527 | HY-13637A | MFCD00873979 | 277.216 | C9H12N5NaO4
Ambeed | Methyl 2-(4455-tetramethyl-132-dioxaborolan-2-yl)-6-(trifluoromethyl)benzoate | 1g | 714083961 | A1536130 | 1146214-79-0 | 330.110 | C15H18BF3O4
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Medchemexpress LLC Esazomide impurity 11 | 69125-10-6 | C3H2ClN3O2 | 100 MG
Esazomide impurity 11 is a chemical compound for laboratory research and the manufacture of substances. It serves as an impurity of Esazomide and is also used as a reference standard.
- A chemical compound for laboratory use
- Identified as an impurity of Esazomide
- Molecular formula: C3H2ClN3O2
- Molecular weight: 147.52
- Appearance: Solid
- Store container tightly sealed in a cool, well-ventilated area
- Keep away from direct sunlight and sources of ignition
- Recommended storage at 4°C under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen