Drug Standards
Medchemexpress LLC Ethyl gallate | 831-61-8 | 198.17 | 1 ML
Ethyl gallate is a nonflavonoid phenolic compound and a scavenger of hydrogen peroxide. It has a cytotoxic effect on HL-60 cells, leading to changes in morphology, shrinkage of the cell membrane, development of apoptotic bodies, and decreased cell viability. It is suitable for laboratory research applications.
- Nonflavonoid phenolic compound
- Scavenger of hydrogen peroxide
- Has cytotoxic effect on HL-60 cells
- Leads to changes in morphology, shrinkage of the cell membrane, development of apoptotic bodies, and decreased cell viability
Medchemexpress LLC Propyl gallate | 121-79-9 | 212.20 | 5 G
Propyl gallate is a common food antioxidant that can inhibit the production of acrolein, glyoxal, and methylglyoxal. It exhibits anti-inflammatory, antitumor, and cardioprotective activities.
- Common food antioxidant.
- Can inhibit the production of acrolein, glyoxal, and methylglyoxal.
- Exhibits anti-inflammatory activities.
- Exhibits antitumor activities.
- Exhibits cardioprotective activities.
Medchemexpress LLC Tyloxapol | 25301-02-4 | 10 G
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, functioning as a surface active stabilizer. It is utilized to induce hyperlipidemia in animals, characterized by high levels of plasma triglycerides and LDL-cholesterol, and reduced HDL-cholesterol. It can increase plasma cholesterol levels by promoting hepatic cholesterol synthesis and disturbing lipolytic enzymes, blocking lipid uptake from circulation.
- Used to induce hyperlipidemia in animals
- Triggers detachment of HEK293 cells
- Induces nuclear fragmentation and apoptotic nuclei
- Increases risk of pulmonary hemorrhage and causes cytotoxicity
- Reduces AChE and MAO enzyme activities in rat plasma and brain
- Leads to reduction in plasma urea, creatinine, and bilirubin
- Appearance: liquid
- Color: colorless to light yellow
Medchemexpress LLC D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate | 87-33-2 | 99.89% | 25 MG
Isosorbide dinitrate (ISDN) is a Nitric Oxide (NO) donor that helps prevent left ventricular (LV) remodeling and degradation of cardiac function following myocardial infarction (MI).
- Synonyms: ISDN
- CAS No.: 87-33-2
- Purity: 99.89%
- Molecular weight: 236.14
- Formula: C6H8N2O8
- Appearance: Solid
- Color: White to off-white
- Handling: For research use only. Not sold to patients.
- Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
- Solubility: In DMSO: 100 mg/mL (423.48 mM); requires ultrasonic and newly opened hygroscopic DMSO.
Medchemexpress LLC Butylparaben | 94-26-8 | 98.9% | 25 G
Butylparaben is an organic compound that serves as an antimicrobial preservative in cosmetics, active molecule suspensions, and as a food flavoring additive. It can also be used in vitro to inhibit porcine oocyte fertilization, cleavage, and blastocyst formation, and in vivo studies have shown no systemic toxicity at certain doses.
- Serves as an antimicrobial preservative
- Can be used in cosmetics and active molecule suspensions
- Functions as a food flavoring additive
- Inhibits porcine oocyte fertilization and development in vitro
- Induces DNA damage, apoptosis, and autophagy in porcine oocytes in vitro
- Shows no systemic toxicity in rats at specific doses in vivo
Medchemexpress LLC Tiamulin | 55297-95-5 | 98.1% | 250 MG
Tiamulin is a diterpenic antibiotic widely used in pigs and poultry to control infectious diseases, particularly airsacculitis caused by Mycoplasma spp. This semisynthetic derivative of Pleuromutilin is highly effective against various Mycoplasma strains, Spirochaetes, and gram-positive bacteria by binding to rRNA and inhibiting protein production. It is less active against gram-negative bacteria. Tiamulin has been shown to be effective in treating avian intestinal spirochaetosis.
- Diterpenic antibiotic for infectious diseases
- Effective against Mycoplasma strains, Spirochaetes, and gram-positive bacteria
- Semisynthetic derivative of Pleuromutilin
- Inhibits protein production by binding to rRNA
- Less active against gram-negative bacteria
- Effective in treating avian intestinal spirochaetosis
Medchemexpress LLC Deacetyl Ganoderic Acid F | 100665-44-9 | 1 MG
Deacetyl Ganoderic Acid F is a 7-anostane triterpenoid from *Ganoderma lucidum*. It is presented as a white to off-white solid with a purity of 98.82%.
- Purity of 98.82%
- Molecular weight: 528.63
- Formula: C30H40O8
- Appearance: White to off-white solid
- Structure classification: Terpenoids, triterpenes
- Initial source: Plants, Polyporaceae
- For research use only
- Store at 4°C, sealed, away from moisture
Medchemexpress LLC (rel)-Tivantinib | 905853-99-8 | MFCD11977597 | 96.45% | C23H19N3O2 | 25 MG
(rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. It also targets GSK3α and GSK3β, which are important in the cellular mechanism of non-small cell lung cancer (NSCLC).
- Potent and highly selective c-MET inhibitor
- Targets GSK3α and GSK3β
- Important in non-small cell lung cancer (NSCLC) cellular mechanisms
Sigma Aldrich Fine Chemicals Biosciences fexofenadine Related Compo50MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Cayman Chemical Esomeprazole 500mg
An H+/K+-ATPase inhibitor; reversibly inhibits the activity of the H+/K+-ATPase in an enzyme assay; inhibits histamine-induced gastric acid secretion in rats at 30 mg/kg, s.c.
Medchemexpress LLC Meropenem trihydrate | 119478-56-7 | 99.9% | 437.51 | 25 MG
Meropenem trihydrate is a carbapenem antibiotic with broad-spectrum antibacterial activity. It inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs).
- Intrinsically stable to dehydropeptidase-1 (DHP-1) degradation
- Broad-spectrum in vitro activity against many Gram-positive, Gram-negative, and anaerobic bacteria
- Targets β-lactam
- Active against susceptible and resistant N. gonorrhoeae, H. influenzae, and H. ducreyi
Medchemexpress LLC Ganciclovir sodium | 107910-75-8 | 99.92% | 277.21 | 1 G
Ganciclovir (BW 759) sodium is a nucleoside analogue and an orally active antiviral agent effective against CMV. It also exhibits in vitro activity against members of the herpes group and other DNA viruses. It inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain.
- Orally active antiviral agent
- Effective against CMV
- Inhibits in vitro replication of human herpes viruses (HSV 1 and 2, CMV)
- Inhibits adenovirus serotypes
- IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)
- Can diffuse into the brain
Medchemexpress LLC Meropenem (trihydrate) (standard) | 119478-56-7 | 100.0% | 437.51 | 100 MG
Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate), a carbapenem antibiotic with broad-spectrum antibacterial activity. It is effective against susceptible and resistant N. gonorrhoeae, H. influenzae, and H. ducreyi. This product is intended for research and analytical applications.
- Analytical standard for meropenem (trihydrate).
- Carbapenem antibiotic with broad-spectrum antibacterial activity.
- Effective against susceptible and resistant N. gonorrhoeae, H. influenzae, and H. ducreyi.
- Suitable for research and analytical applications, including HPLC, GC, and MS.
Medchemexpress LLC Rosuvastatin lactone | 503610-43-3 | 97.0% | 463.52 | 25 MG
Rosuvastatin lactone is a metabolite of Rosuvastatin and an HMG-CoA inhibitor. It is intended for research use only.
- Metabolite of Rosuvastatin
- HMG-CoA inhibitor
- For research use only
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO (125 mg/mL)
Medchemexpress LLC Mitotane | 53-19-0 | 320.04 | 1 ML
Mitotane (2,4′-DDD) is an isomer of DDD and a derivative of dichlorodiphenyltrichloroethane (DDT). It acts as an antineoplastic agent primarily used in adrenocortical carcinoma research. Its adrenocorticolytic effect is exerted, in part, through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can also influence corticotroph cells in the pituitary and activate CYP3A4 gene expression via steroid and xenobiotic receptor (SXR).
- Used as an antineoplastic agent in adrenocortical carcinoma research
- Exerts adrenocorticolytic effect through lipotoxicity
- Induces CYP3A4 gene expression via SXR activation
- Can have direct pituitary effects on corticotroph cells