Drug Standards
Medchemexpress LLC Cephalexin monohydrate (cefalexin hydrate) | 23325-78-2 | 99.6% | 1 ML
Cephalexin monohydrate is a potent, orally active semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. It demonstrates antibacterial activity against a wide variety of gram-positive and gram-negative bacteria, and targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. This product is for research use only.
- Potent, orally active semisynthetic cephalosporin antibiotic
- Broad antibacterial spectrum
- Active against gram-positive and gram-negative bacteria
- Targets penicillin-binding proteins (PBPs)
- Inhibits bacterial cell wall assembly
- Used for research of pneumonia, strep throat, and bacterial endocarditis
Selleck Chemical LLC LGK-974
LGK-974 (NVP-LGK974 WNT974) is a potent and specific PORCN inhibitor and inhibits Wnt signaling with IC50 of 0 4 nM in TM3 cells Phase 1
Medchemexpress LLC Flavopiridol (alvocidib) | 146426-40-6 | 401.84 g/mol | C21H20ClNO5 | 500 MG
Flavopiridol is a broad-spectrum, ATP-competitive inhibitor of cyclin-dependent kinases used in research to probe cell-cycle regulation and kinase signaling. It inhibits CDK1, CDK2, and CDK4 with reported IC50s of 30 nM, 170 nM, and 100 nM, respectively. Supplied as a solid research reagent with documented solubility and storage recommendations.
Medchemexpress LLC NF023 hexasodium | 104869-31-0 | MFCD01074985 | 100.0% | 1162.88 g·mol⁻¹ | C35H20N4Na6O21S6 | 5 MG
NF023 hexasodium is the hexasodium salt of NF023, a selective and competitive antagonist of the P2X1 receptor used in research applications. It exhibits an IC50 of 0.21 μM for human P2X1 and markedly reduced activity at other P2X subtypes. Supplied as a high-purity dry solid in milligram quantities for laboratory assays and screening; for research use only.
- Selective P2X1 receptor antagonist with reported IC50 of 0.21 μM.
- High purity to support experimental reproducibility.
- Available in small milligram sizes suitable for in vitro studies.
- Provided as the hexasodium salt with defined molecular weight and formula.
- For research use only; not for human or veterinary use.
Medchemexpress LLC (R)-tert-butyl piperidin-3-yl carbamate (linagliptin impurity 9) | 2279114-27-9 | 10mg
Linagliptin impurity 9 is an impurity of Linagliptin (HY-10284)
U.S. Pharmacopeia Risperidone | 106266-06-2 | 100mg
Risperidone | Mol Wt: 410.48 | 106266-06-2 | 100mg
Medchemexpress LLC Fexofenadine hydrochloride | 153439-40-8 | 99.9% | 5 MG
Fexofenadine hydrochloride is an orally active and nonsedative H1 receptor antagonist. It can be used in allergic rhinitis and chronic idiopathic urticarial research.
- Orally active
- Nonsedative H1 receptor antagonist
- Can be used in allergic rhinitis research
- Can be used in chronic idiopathic urticarial research
- Inhibits the expression of IL-6 protein in nasal fibroblasts in a dose-dependent manner
- Blocks phosphorylated p38 activation in histamine-induced nasal fibroblasts
- Suppresses eosinophilia and systemic anaphylaxis in T. spiralis infected mice
Medchemexpress LLC Ganoderic acid D | 108340-60-9 | MFCD32197327 | 99.4% | 514.65 g/mol | C30H42O7 | 10 MG
Ganoderic acid D is a tetracyclic triterpenoid supplied as a high-purity analytical standard for laboratory research. It is commonly used as a biochemical reagent and reference standard in apoptosis and metabolic studies, and is provided with supporting documentation for safe handling and analytical use.
- High purity (99.4%) analytical standard for research use.
- Tetracyclic triterpenoid suitable for biochemical and cellular assays.
- Provided with certificate of analysis and safety data sheet for quality control.
- Available in small milligram quantities for analytical workflows.
- Molecular weight 514.65 g/mol; CAS 108340-60-9.
Sigma Aldrich Fine Chemicals Biosciences Alimemazine for system suitability European Pharmacopoeia (EP) Reference Standard | 4330-99-8 |
Alimemazine for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 373.49 | 4330-99-8 |
Medchemexpress LLC 25-desacetyl rifampicin | 16783-99-6 | MFCD08063717 | >95.0% | 780.90 | C41H56N4O11 | 5MG
25-Desacetyl rifampicin is the deacetylated metabolite of rifampicin provided as an isotope-labeled (deuterated) reference standard for research use. It is intended for analytical quantitation and ADME/pharmacokinetic studies as a tracer or internal standard. The compound has CAS 16783-99-6, molecular formula C41H56N4O11, and molecular weight 780.90 g/mol. Documentation including a data sheet and safety data sheet is available from the supplier.
- Deuterated isotope-labeled reference standard.
- Suitable for pharmacokinetic and metabolic studies.
- High purity (≥95%).
- Molecular formula C41H56N4O11; molecular weight 780.90 g/mol.
- Available in small research pack sizes (1 mg-50 mg).
- Data sheet and safety data sheet available.
Selleck Chemical LLC Tazarotene 10mg 118292-40-3 AGN190168
Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Porcn-IN-1 | 2036044-77-4 | 99.57% | 410.44 | 1 ML
Porcn-IN-1 is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM. It potently inhibits the secretion of Wnt3A, confirming its role as a porcupine inhibitor. Porcupine is an enzyme that catalyzes the addition of palmitoleate to a serine residue in Wnt proteins, a process essential for Wnt protein secretion. Porcn-IN-1 is as potent as the clinical compound LGK974 in a cell-based STF reporter gene assay.
- Potent porcupine inhibitor: IC50 of 0.5±0.2 nM.
- Confirmed inhibition: Potently inhibits the secretion of Wnt3A.
- Comparable to clinical compound: As potent as LGK974 in a cell-based STF reporter gene assay.
- Moderate clearance: Demonstrates moderate clearance in human and rat liver microsomes (57 mL/min/kg and 24 mL/min/kg respectively).
- High clearance in mouse microsomes: Exhibits high clearance in mouse microsomes (109 mL/min/kg).
Cayman Chemical EthacrynIc AcId 1g
A loop diuretic with anticancer activity; inhibits the NKCC cotransporter in duck erythrocytes (IC50 = 0.18 mM); inhibits ATP-dependent chloride uptake in rat renal plasma membrane vesicles at 0.3 mM; inhibits GSTP1-1 and GSTA3-3 (IC50s = 4.9 and ~0.4 μM, respectively); inhibits Wnt/β-catenin signaling in a cell-based reporter assay; cytotoxic to primary chronic lymphocytic leukemia cells (IC50 = 8.56 μM), as well as MCF-7, MDA-MB-231, and 4T1 cancer cells (IC50s = 45.53, 39.64, and 25.23 μM, respectively); increases tumor growth reduction induced by afatinib or neratinib in a 4T1 murine breast cancer model at 250 μg per day
Apexbio Technology LLC Amitriptyline HCl 549-18-8 1g
Amitriptyline HCl (CAS 549-18-8) is a tricyclic compound that modulates multiple neurotransmitter systems It acts as an inhibitor at serotonin and norepinephrine receptors demonstrating potent activity with IC50 values of 3 45 nM and 13 3 nM respectively Amitriptyline also exhibits notable affinity for 5-HT4 (IC50 7 31 nM) 5-HT2 (IC50 235 nM) and sigma-1 receptors (IC50 287 nM) indicating a broad spectrum of receptor interactions This pharmacological profile supports its application in neuropharmacological research including studies of synaptic transmission antidepressant mechanisms and receptor signaling pathways
Medchemexpress LLC Cefpodoxime Proxetil | 87239-81-4 | 10 MG
Cefpodoxime Proxetil is an orally active, broad-spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria. It functions by binding to penicillin-binding proteins (PBPs), inhibiting peptidoglycan synthesis, and interfering with bacterial cell wall biosynthesis.
- Orally active, broad-spectrum third-generation cephalosporin
- Exhibits potent antibacterial activity against Gram-positive and Gram-negative bacteria
- Inhibits peptidoglycan synthesis
- Interferes with bacterial cell wall biosynthesis
- Used to treat skin structure infections
- Used to treat acute otitis media
- Used to treat pharyngitis
- Used to treat tonsillitis
- Used to treat upper respiratory tract infections
- Used to treat urinary tract infections
- Used to treat sexually transmitted diseases