Drug Standards
Med Vet International Diphenhydramine Capsules 25mg, 100 Tablets
Diphenhydramine Capsules 25mg, 100 TabletsProducts are not always manufacturer specific. Actual product appearance may differ from website image.
Medchemexpress LLC Enzastaurin (LY317615) | 170364-57-5 | 99.8% | 515.61 | 10 MG
Enzastaurin (LY317615) is a potent, selective, and CNS-penetrant PKCβ inhibitor with an IC50 of 6 nM, showing 6- to 20-fold selectivity over PKCα, PKCγ and PKCε.
- Potent, selective, and CNS-penetrant PKCβ inhibitor
- Induces apoptosis and suppresses proliferation in cultured tumor cells
- Suppresses the phosphorylation of GSK3βser9, ribosomal protein S6S240/244, and AKTThr308
- Increases apoptosis in malignant lymphocytes of CTCL
- When combined with GSK3 inhibitors, enhances cytotoxicity levels
- Treatment with Enzastaurin and radiation produces greater reductions in density of microvessels and delays tumor growth in xenografts
TARGETMOL CHEMICALS INC Flutriafol 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist Purity 98.75%
Selleck Chemical LLC Gandotinib (LY2784544) 5mg 1229236-86-5
Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Ketoconazole | 65277-42-1 | 99.6% | C26H28Cl2N4O4 | 1 G
Ketoconazole is an imidazole anti-fungal agent and a CYP3A4 and CYP24A1 inhibitor. It has been shown to produce features of androgen deficiency and is a potent exosome biogenesis and/or secretion inhibitor. This product is for research use only.
- Functions as an imidazole anti-fungal agent
- Acts as a CYP3A4 and CYP24A1 inhibitor
- Inhibits hepatic CYP450 and CYT b5 activities
- Enhances antiproliferative effects
- Increases systemic calcitriol exposure
- Promotes activation of caspase-independent apoptosis
- Potent exosome biogenesis and/or secretion inhibitor
Medchemexpress LLC Docetaxel Trihydrate | 148408-66-6 | 99.91% | 1 ML
Docetaxel Trihydrate is an antineoplastic agent that inhibits microtubule depolymerization. It is a semisynthetic analog of taxol and works by attenuating the effects of bcl-2 and bcl-xL gene expression. This leads to the arrest of the cell cycle at G2/M and subsequent cell apoptosis. It is intended for research use only.
- Inhibits microtubule depolymerization
- Semisynthetic analog of taxol
- Attenuates effects of bcl-2 and bcl-xL gene expression
- Arrests the cell cycle at G2/M
- Leads to cell apoptosis
Medchemexpress LLC Hexanoylglycine-d11 | 24003-67-6 | 99.7% | 184.28 | 10 MG
Hexanoylglycine-d11 is the deuterium labeled Hexanoylglycine. It can be used as a tracer and as an internal standard for quantitative analysis. Deuteration, the substitution of deuterium for hydrogen, has gained attention for its potential impact on the pharmacokinetic and metabolic profiles of drugs. Stable heavy isotopes like hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Selleck Chemical LLC Elacridar
Elacridar (GF120918 GW120918 GG918 GW0918) is a potent P-gp (MDR-1) and BCRP inhibitor
Selleck Chemical LLC Vinorelbine Tartrate 50mg 125317-39-7
Vinorelbine Tartrate is a semi-synthetic vinca alkaloid, and inhibits mitosis through interaction with tubulin. Vinorelbine Tartrate exhibits anti-tumor activities via inducing the mitotic apoptosis, autophagy and inflammation. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Binimetinib
Binimetinib (MEK162 ARRY-162 ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy Phase 3
Selleck Chemical LLC Loratadine S1358-10mg
Loratadine is a histamine H1 receptor antagonist used to treat allergies Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 M
TARGETMOL CHEMICALS INC Bromfenac sodium hydrate 500MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. Upon ophthalmic administration, bromfenac binds to and inhibits cyclooxygenase II (COX II), an enzyme that converts arachidonic acid to cyclic endoperoxides, which are prostaglandin (PG) precursors. By inhibiting PG formation, bromfenac prevents PG-induced inflammation, vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, increased vascular permeability, and elevated intraocular pressure (IOP). Purity 99.65%
TARGETMOL CHEMICALS INC Temozolomide 200MG
Also available in 1 g, 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions. Purity 99.87%
TARGETMOL CHEMICALS INC Ranitidine 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. Purity 99.1%
TARGETMOL CHEMICALS INC Harpagoside 20MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells. Purity 100%