Drug Standards
Medchemexpress LLC Propyl gallate | 121-79-9 | 212.20 | 5 G
Propyl gallate is a common food antioxidant that can inhibit the production of acrolein, glyoxal, and methylglyoxal. It exhibits anti-inflammatory, antitumor, and cardioprotective activities.
- Common food antioxidant.
- Can inhibit the production of acrolein, glyoxal, and methylglyoxal.
- Exhibits anti-inflammatory activities.
- Exhibits antitumor activities.
- Exhibits cardioprotective activities.
Medchemexpress LLC Tyloxapol | 25301-02-4 | 10 G
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, functioning as a surface active stabilizer. It is utilized to induce hyperlipidemia in animals, characterized by high levels of plasma triglycerides and LDL-cholesterol, and reduced HDL-cholesterol. It can increase plasma cholesterol levels by promoting hepatic cholesterol synthesis and disturbing lipolytic enzymes, blocking lipid uptake from circulation.
- Used to induce hyperlipidemia in animals
- Triggers detachment of HEK293 cells
- Induces nuclear fragmentation and apoptotic nuclei
- Increases risk of pulmonary hemorrhage and causes cytotoxicity
- Reduces AChE and MAO enzyme activities in rat plasma and brain
- Leads to reduction in plasma urea, creatinine, and bilirubin
- Appearance: liquid
- Color: colorless to light yellow
Medchemexpress LLC Butylparaben | 94-26-8 | 98.9% | 25 G
Butylparaben is an organic compound that serves as an antimicrobial preservative in cosmetics, active molecule suspensions, and as a food flavoring additive. It can also be used in vitro to inhibit porcine oocyte fertilization, cleavage, and blastocyst formation, and in vivo studies have shown no systemic toxicity at certain doses.
- Serves as an antimicrobial preservative
- Can be used in cosmetics and active molecule suspensions
- Functions as a food flavoring additive
- Inhibits porcine oocyte fertilization and development in vitro
- Induces DNA damage, apoptosis, and autophagy in porcine oocytes in vitro
- Shows no systemic toxicity in rats at specific doses in vivo
Apexbio Technology LLC Methylprednisolone Sodium Succinate 2375-03-3 10mg
Methylprednisolone sodium succinate is a synthetic glucocorticoid with anti-inflammatory and immunomodulatory activity routinely utilized as an experimental tool in inflammation immune response and neural injury studies Mechanistically it binds cytoplasmic glucocorticoid receptors modulating transcriptional activity to suppress cytokine release reduce circulating lymphocyte counts and promote apoptosis and differentiation in responsive cells In vitro assays demonstrate inhibition of neutrophil-mediated chemotaxis and suppression of reactive oxygen species production at high concentrations ( 1 mg/ml) whereas lower concentrations (0 04 0 22 mM) exhibit minimal effects The IC50 values reported for suppression of neutrophil chemiluminescence and oxidant generation are approximately in the millimolar range (around 2 7 mM) Clinically it has been studied for central nervous system injuries including spinal cord trauma
Sigma Aldrich Fine Chemicals Biosciences Cefprozil Related Compound D United States Pharmacopeia (USP) Reference Standard | 106447-44-3 | 30MG
Cefprozil Related Compound D United States Pharmacopeia (USP) Reference Standard | Mol Wt: 240.28 | 106447-44-3 | 30MG
Cayman Chemical Esomeprazole 500mg
An H+/K+-ATPase inhibitor; reversibly inhibits the activity of the H+/K+-ATPase in an enzyme assay; inhibits histamine-induced gastric acid secretion in rats at 30 mg/kg, s.c.
Medchemexpress LLC Ganciclovir sodium | 107910-75-8 | 99.92% | 277.21 | 1 G
Ganciclovir (BW 759) sodium is a nucleoside analogue and an orally active antiviral agent effective against CMV. It also exhibits in vitro activity against members of the herpes group and other DNA viruses. It inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain.
- Orally active antiviral agent
- Effective against CMV
- Inhibits in vitro replication of human herpes viruses (HSV 1 and 2, CMV)
- Inhibits adenovirus serotypes
- IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)
- Can diffuse into the brain
Medchemexpress LLC Mifepristone (Standard) | 84371-65-3 | 99.4% | 429.59 | 50 MG
Mifepristone (Standard) is an analytical standard intended for research and analytical applications. It acts as a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist. This standard is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist
- Suitable for HPLC, GC, and MS experiments
Medchemexpress LLC Mifepristone (standard) | 84371-65-3 | 99.4% | 429.59 | 100 MG
Mifepristone (Standard) is an analytical standard of Mifepristone, also known as RU486. It functions as an antagonist for progesterone receptor (PR) and glucocorticoid receptor (GR), exhibiting IC50s of 0.2 nM and 2.6 nM respectively in in vitro assays. This product is designed for research and analytical applications.
- Intended for research and analytical applications
- Functions as a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
- Serves as a reference standard supplied assay
TARGETMOL CHEMICALS INC Divalproex Sodium 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes.Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC inhibitor， Comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex may also work by suppressing repetitive neuronal firing through the inhibition of voltage-sensitive sodium channels. Purity 99.84%
Medchemexpress LLC (S)-Donepezil | 142057-80-5 | 99.8% | C24H29NO3 | 25 MG
(S)-Donepezil is the S-enantiomer of Donepezil, a specific and potent Acetylcholinesterase (AChE) inhibitor. It appears as a white to off-white solid and is intended for research use only.
- Specific and potent Acetylcholinesterase (AChE) inhibitor.
- Chemical formula: C24H29NO3.
- Molecular weight: 379.49.
- Soluble in DMSO (100 mg/mL).
- Recommended storage for powder: -20°C for 3 years or 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC Aminopterin | 54-62-6 | 98.7% | C19H20N8O5 | 50 MG
Aminopterin, also known as 4-Aminofolic acid, is a powerful folic acid antagonist. It operates by catalyzing the reduction of folic acid to tetrahydrofolic acid and competitively inhibits dihydrofolate reductase (DHFR) with a high affinity (Ki of 3.7 pM). This compound is recognized for its significant anticancer and immunosuppressive activities, making it a valuable agent in medical applications, particularly in the treatment of pediatric leukemia.
- Acts as a folic acid antagonist
- Competitively inhibits dihydrofolate reductase (DHFR)
- Exhibits anticancer properties
- Possesses immunosuppressive activities
- Used in the treatment of pediatric leukemia
Medchemexpress LLC Milrinone | 78415-72-2 | 99.9% | C12H9N3O | 500 MG
Milrinone is a potent PDE3 inhibitor, also functioning as an inotrope and vasodilator. This product is intended for research use only and is not for patient administration.
- Potent PDE3 inhibitor
- Functions as an inotrope and vasodilator
- Appears as a solid, white to off-white powder
- Soluble in DMSO at 50 mg/mL
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Escitalopram oxalate (Standard) | 219861-08-2 | 99.98% | C22H23FN2O5 | 50 MG
Escitalopram oxalate (Standard) is an analytical standard for research and analytical applications. It is the S-enantiomer of racemic Citalopram, acting as a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. It shows high binding affinity and selectivity over dopamine and norepinephrine transporters, making it useful in major depression research.
- Analytical standard for research and analytical applications
- Functions as a selective serotonin reuptake inhibitor (SSRI)
- Used in qualitative, quantitative, and methodological research
- Suitable for HPLC, GC, and MS
- Antidepressant for major depression research
- High binding affinity and selectivity over other transporters
Medchemexpress LLC Zileuton | 111406-87-2 | MFCD00866097 | 99.6% | C11H12N2O2S | 100 MG
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties, intended for research use only.
- Potent and selective inhibitor of 5-lipoxygenase
- Has antiasthmatic properties
- Available as a solid
- Melting point is 157-158°C
- Stable under recommended storage conditions
- Identified for laboratory chemical uses