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Filtered Search Results
Cayman Chemical Mevastatin Inhibitors
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An HMG-CoA reductase inhibitor (Ki = 0.1 µM); inhibits cholesterogenesis in the liver and ileum of normolipidemic rats, as well as enhances suppression of cholesterogenesis in cholesterol-fed rats or rats administered cholestyramine at 50 mg/kg; suppresses TNF-induced NF-κB activation (IC50 = ~17 µM) and potentiates apoptosis in human myeloid leukemia cells; suppresses induced ferroptosis in HT-1080 cells
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000734323 MELOXICAM IMPURITY 5 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669611 ESCULIN STANDARD 10MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000396626 PTH-RELATED PROTEIN 5MG
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Selleck Chemical LLC Hydrochlorothiazide S1708-50mg
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Hydrochlorothiazide is a first line diuretic compound of the thiazide class
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000739338 RIVAROXABAN IMPURITY 5G
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Selleck Chemical LLC Isoprenaline (Isoproterenol) HCl S2566-1g
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Isoprenaline (Isoproterenol) HCl is a non-selective beta-adrenergic receptor agonist used for the treatment of bradycardia and heart block
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Selleck Chemical LLC Osimertinib mesylate S5078-1g
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Osimertinib mesylate (AZD9291) is the mesylate form of osimertinib which is an oral third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug
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Selleck Chemical LLC Fostamatinib (R788) S2625-10mM/1mL
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Fostamatinib (R788) a prodrug of the active metabolite R406 is a Syk inhibitor with IC50 of 41 nM strongly inhibits Syk but not Lyn 5-fold less potent to Flt3 Phase 3
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Selleck Chemical LLC Flavopiridol (Alvocidib) HCl S2679-1g
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Flavopiridol (Alvocidib) HCl competes with ATP to inhibit CDKs including CDK1 CDK2 CDK4 and CDK6 with IC50 of 40 nM in cell-free assays It is 7 5-fold more selective for CDK1/2/4/6 than CDK7 Flavopiridol is initially found to inhibit EGFR and PKA Flavopiridol HCl induces autophagy and ER stress Flavopiridol HCl blocks HIV-1 replication Phase 1/2
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Medchemexpress LLC Bumetanide | 28395-03-1 | 99.9% | 364.42 | 50 MG
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Bumetanide (Standard) is the analytical standard of Bumetanide. It is a highly potent loop diuretic and a Na+-K+-Cl+ cotransporter (NKCC) blocker, commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard
- Highly potent loop diuretic
- Na+-K+-Cl+ cotransporter (NKCC) blocker
- Selective NKCC1 inhibitor
- Inhibits NKCC2
- Intended for research and analytical applications
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
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Medchemexpress LLC Salinomycin (sodium salt) | 55721-31-8 | MFCD00078044 | 99.8% | 772.98 | 50 MG
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Salinomycin (sodium salt) | 55721-31-8 | MFCD00078044 | 99.8% | 772.98 | 50 MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669967 CANAGLIFLOZIN IMPURI 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669951 CANAGLIFLOZIN IMPURI 5MG
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Cayman Chemical R-FlurbIprofen 100mg
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A COX-inactive enantiomer of flurbiprofen; inhibits γ-secretase activity in vitro; reduces formation of Aβ42 and improves axonal transport in young Aβ-plaque free mice in the Tg2576 transgenic model of Alzheimer's disease; inhibits NF-kB activation and DNA binding as well as AP-1 DNA binding in RAW 264.7 macrophages; reduces paw edema in a rat model of zymosan-induced inflammation at 1, 3, and 9 mg/kg; suppresses prostate tumor cell growth in vitro and reduces tumor growth and metastasis in multiple mouse models of intestinal neoplasia
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