Drug Standards
Cayman Chemical N-Despropyl RopInIrole 25mg
An active metabolite of ropinirole; increases extracellular acidification rates in CHO cells expressing human dopamine D2, D3, and D4 receptors (EC50s = 0.63, 0.063, and 1.23 µM, respectively); a potential impurity found in commercial preparations of ropinirole
Apexbio Technology LLC Metoclopramide 364-62-5 10mM (in 1mL DMSO)
Metoclopramide (CAS 364-62-5) is a small molecule that primarily acts as an antagonist at dopamine D2 receptors and also exhibits mixed activity as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist Through inhibition of D2 dopaminergic signaling it enhances gastrointestinal motility and exerts antiemetic effects Metoclopramide has been extensively investigated for applications in managing gastrointestinal disorders such as gastroparesis and gastroesophageal reflux disease as well as for alleviating nausea and vomiting including in pregnant women Research supports the safety profile of this compound for fetal outcomes when administered during pregnancy reinforcing its utility in reproductive and gastrointestinal pharmacology studies
Cayman Chemical Ketoconazole 1g
A triazole antifungal agent; has activity against C. albicans, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. neoformans, and A. fumigatus strains (IC50s = 0.031-8 UG/ml); inhibits fungal CYP51; inhibits human CYP3A4 (IC50 = 0.54 µM)
![Medchemexpress LLC (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide | 1637254-93-3 | 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide | 1637254-93-3 | 25mg
Afatinib impurity 95 (Bromo-Afatinib) is an impurity of Afatinib (HY-10261)
Medchemexpress LLC Methyl (2R)-2-amino-2-(2-chlorophenyl)acetate hydrochloride | 212838-70-5 | MFCD08457889 | 5g
Clopidogrel impurity 2 is an impurity of Clopidogrel (HY-15283)
Sigma Aldrich Fine Chemicals Biosciences fenofibrate United States200mg
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Apexbio Technology LLC Ritodrine HCl 23239-51-2 500mg
Ritodrine hydrochloride (CAS 23239-51-2) is a selective 2-adrenergic receptor agonist that modulates smooth muscle activity By stimulating 2-adrenergic receptors ritodrine promotes uterine muscle relaxation thereby inhibiting premature uterine contractions Comparative studies indicate that ritodrine can rapidly extend the interval before delivery although it is associated with a higher incidence of adverse effects compared to alternatives such as magnesium sulfate Ritodrine HCl is widely used in research to investigate 2-adrenergic signaling pathways and to model the pharmacological regulation of preterm labor
Apexbio Technology LLC Ciprofloxacin 85721-33-1 5g
Ciprofloxacin (85721-33-1) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV It is designed to inhibit these enzymes thereby disrupting bacterial DNA replication and transcription Ciprofloxacin exerts its biological activity primarily through inhibition of DNA gyrase and topoisomerase IV In in vitro and cell-based studies Ciprofloxacin demonstrates inhibitory activity with IC50 values ranging from approximately 0 1 g/mL to 2 5 g/mL depending on the bacterial strain and assay conditions Based on these pharmacological properties Ciprofloxacin holds research potential in studies of DNA enzymology bacterial gene regulation and antimicrobial resistance mechanisms
Apexbio Technology LLC S-Ruxolitinib (INCB018424) 941685-37-6 1mg
S-Ruxolitinib (INCB018424 CAS 941685-37-6) is the chiral form of ruxolitinib acting as a selective inhibitor of Janus kinases JAK1 and JAK2 By competitively blocking the ATP-binding site within the kinase domain S-Ruxolitinib disrupts JAK-STAT pathway signaling which is essential for the function of various cytokine and growth factor receptors involved in hematopoiesis and immune regulation In studies using JAK2V617F-positive Ba/F3 cells ruxolitinib has been shown to reduce cellular proliferation This compound is widely utilized in research to investigate JAK-mediated signal transduction and to explore therapeutic strategies targeting aberrant JAK activity in hematologic disorders
Apexbio Technology LLC Cefditoren Pivoxil 117467-28-4 50mg
Cefditoren pivoxil is a small-molecule prodrug antibiotic targeting penicillin-binding proteins It is designed to inhibit these proteins thereby disrupting peptidoglycan cross-linking essential for bacterial cell wall integrity Cefditoren pivoxil exerts its biological activity primarily through inhibition of bacterial cell wall synthesis This mechanism confers bactericidal activity against a broad range of Gram-positive and Gram-negative organisms Based on these pharmacological properties cefditoren pivoxil holds research potential in studying bacterial susceptibility profiles characterizing resistance mechanisms in pathogens and evaluating pharmacokinetic-pharmacodynamic relationships associated with cephalosporins
Sigma Aldrich Fine Chemicals Biosciences folic acid US P500MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Sigma Aldrich Fine Chemicals Biosciences Colchicine suitable for pl5G
Colchicine is a tricyclic alkaloid that can stay in circulation for 20 to 40 hours post intake. Leucocytes harbour maximum colchicine. It contains three hexameric rings termed A B and C.
Cyclodextrin Technologies Development TRAPPSOL HYDRO BETACYC 5GM
Beta Cyclodextrin derivative for enhanced solubility >50g/100ml - meets USP/EP standards