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Filtered Search Results
Medchemexpress LLC S2116 | 2262489-89-2 | 98.1% | 437.91 | 50 MG
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S2116 is an N-alkylated tranylcypromine (TCP) derivative and a potent lysine-specific demethylase 1 (LSD1) inhibitor. It enhances H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 can induce apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by suppressing the transcription of NOTCH3 and TAL1 genes and has been shown to significantly slow the growth of T-ALL cells in xenotransplanted mice.
- Potent lysine-specific demethylase 1 (LSD1) inhibitor
- Effective for T-ALL cell lines with IC50 values ranging from 1.1 μM to 6.8 μM
- Induces apoptosis and down-regulates NOTCH3 and TAL1 protein expression in T-ALL cells
- Significantly reduces subcutaneous tumor size in xenotransplanted mice
- Exhibits favorable pharmacokinetic properties in mice with a T1/2 of 3.76 hours
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eMolecules 61291-21-2 | 5-Methylthiazole-2-carboxylic acid | Ambeed | MFCD08060736 | 143.160 | C5H5NO2S | 95.000 | Cc1cnc(s1)C(O)=O | 250mg | 524990445
5-Methylthiazole-2-carboxylic acid | Ambeed | 61291-21-2 | MFCD08060736 | 143.160 | C5H5NO2S | 95.000 | Cc1cnc(s1)C(O)=O | 250mg | 524990445
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eMolecules 42438-89-1 | Medchem Express | Pinostilbene | 5mg | 599151211 | HY-N3059 | MFCD12407153 | 242.274 | C15H14O3
AstaTech | 3-PHENYLPROPIOLONITRILE | 1g | 233627790 | 36388 | 95.000 | 935-02-4 | MFCD19300770 | 127.146 | C9H5N
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eMolecules 214139-26-1 | Ambeed | 1-(Boc-amino)-1-indanecarboxylic Acid | 250mg | 506391265 | A547721 | MFCD00800596 | 277.32 | C15H19NO4
Ambeed | N-(4-(4455-Tetramethyl-132-dioxaborolan-2-yl)phenyl)acrylamide | 1g | 595930997 | A1372127 | 434898-99-4 | 273.140 | C15H20BNO3
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eMolecules 612-20-4 | ChemScene | 2-Hydroxymethyl benzoic acid | 5g | 536779344 | CS-0028786 | MFCD02151998 | 152.149 | C8H8O3
ChemScene | 2-Hydroxymethyl benzoic acid | 5g | 536779344 | CS-0028786 | 612-20-4 | MFCD02151998 | 152.149 | C8H8O3
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eMolecules 446866-87-1 | Ambeed | 3-Morpholinobenzaldehyde | 100mg | 624121189 | A446045 | MFCD07772811 | 191.23 | C11H13NO2
ChemScene | 5-Bromo-4-methyl-1H-benzo[d]imidazole | 100mg | 582640735 | CS-W022329 | 952511-48-7 | MFCD18642426 | 211.062 | C8H7BrN2
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![eMolecules 37663-44-8 | Ambeed | 3H-Spiro[isobenzofuran-14-piperidine] hydrochloride | 100mg | 521456653 | A167510 | MFCD02179146 | 225.72 | C12H16ClNO](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502435647.JPG-250.jpg)
eMolecules 37663-44-8 | Ambeed | 3H-Spiro[isobenzofuran-14-piperidine] hydrochloride | 100mg | 521456653 | A167510 | MFCD02179146 | 225.72 | C12H16ClNO
Ambeed | (E)-3-(6-((E)-3-(Pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridin-2-yl)acrylic acid | 1mg | 761012450 | A158908 | 87848-99-5 | MFCD00869830 | 348.446 | C22H24N2O2
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eMolecules 287118-97-2 | Medchem Express | NCX4040 | 5mg | 784543586 | HY-103385 | MFCD08062164 | 331.28 | C16H13NO7
ChemScene | 57-Dimethyl-[124]triazolo[15-a]pyrimidin-2-ylamine | 100mg | 718356394 | CS-0033788 | 7135-02-6 | MFCD00227025 | 163.184 | C7H9N5
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Medchemexpress LLC (E)-2-(((5-bromothiophen-2-yl)methylene)amino)benzamide | 304456-62-0 | 98.0% | 309.18 | C12H9BrN2OS | 5MG
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BTYNB is a small-molecule research inhibitor of IMP1 (IGF2BP1) that disrupts IMP1 binding to c-Myc mRNA, resulting in reduced c-Myc expression and decreased proliferation in IMP1-positive cancer cell lines. The compound is supplied as a solid reagent in multiple sizes and as a 10 mM solution in DMSO for convenient stock preparation, and is reported with high purity for in vitro applications.
- Inhibits IMP1 binding to c-Myc mRNA with reported IC50 ≈ 5 μM.
- High reported purity suitable for in vitro research applications.
- Available in multiple solid pack sizes and a 10 mM solution format in DMSO.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Used to study RNA-protein interactions and cancer cell proliferation.
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eMolecules 1034975-62-6 | Ambeed | 4-(4-Methylpiperazin-1-yl)-2-(222-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzoic acid 222-trifluoroacetate | 1g | 682928952 | A1443632 | 529.436 | C21H25F6N3O6
Ambeed | 2-Amino-44-dimethylpentanoic acid | 250mg | 722704710 | A458749 | 106247-35-2 | MFCD00066078 | 145.202 | C7H15NO2
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eMolecules 54221-96-4 | 6-Methoxypicolinaldehyde | Ambeed | MFCD05664030 | 137.138 | C7H7NO2 | 97.000 | COc1cccc(C=O)n1 | 1g | 552717491
6-Methoxypicolinaldehyde | Ambeed | 54221-96-4 | MFCD05664030 | 137.138 | C7H7NO2 | 97.000 | COc1cccc(C=O)n1 | 1g | 552717491
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eMolecules 13205-48-6 | 4-(Methylthio)benzoic acid | Ambeed | MFCD00002555 | 168.210 | C8H8O2S | 98.000 | CSc1ccc(cc1)C(O)=O | 1g | 672838863
4-(Methylthio)benzoic acid | Ambeed | 13205-48-6 | MFCD00002555 | 168.210 | C8H8O2S | 98.000 | CSc1ccc(cc1)C(O)=O | 1g | 672838863
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 24650-42-8 | 2,2-Dimethoxy-2-phenylacetophenone | Ambeed | MFCD00008475 | 256.301 | C16H16O3 | 98.000 | COC(OC)(C(=O)c1ccccc1)c1ccccc1 | 25g | 570996200
2,2-Dimethoxy-2-phenylacetophenone | Ambeed | 24650-42-8 | MFCD00008475 | 256.301 | C16H16O3 | 98.000 | COC(OC)(C(=O)c1ccccc1)c1ccccc1 | 25g | 570996200
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / Fmoc-D-3-Pal-OH / 250mg / 521408303 / A149266 / / 142994-45-4 / MFCD00080267 / 388.423 / C23H20N2O4
Ambeed / Fmoc-D-3-Pal-OH / 250mg / 521408303 / A149266 / / 142994-45-4 / MFCD00080267 / 388.423 / C23H20N2O4
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 944907-28-2 | 6-Fluoro-benzooxazole-2-carboxylic acid | J&W PharmLab LLC | MFCD10696575 | 181.122 | C8H4FNO3 | 96.000 | OC(=O)c1nc2ccc(F)cc2o1 | 250mg | 761737217
6-Fluoro-benzooxazole-2-carboxylic acid | J&W PharmLab LLC | 944907-28-2 | MFCD10696575 | 181.122 | C8H4FNO3 | 96.000 | OC(=O)c1nc2ccc(F)cc2o1 | 250mg | 761737217
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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