Acetylides
Medchemexpress LLC Propargyl-PEG4-Br | 1308299-09-3 | 5 G
Propargyl-PEG4-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Acts as a non-cleavable ADC linker
- Utilized in the synthesis of antibody-drug conjugates (ADCs)
- Serves as a click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC Propargyl-PEG4-Br | 1308299-09-3 | 1 G
Propargyl-PEG4-Br is a PEG-based PROTAC linker and a non-cleavable ADC linker. It is used in the synthesis of PROTACs and antibody-drug conjugates (ADCs). This click chemistry reagent contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with Azide group-containing molecules. PROTACs selectively degrade target proteins using the ubiquitin-proteasome system, while ADCs attach cytotoxins to antibodies via linkers.
- Functions as a PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Acts as a non-cleavable ADC linker
- Facilitates synthesis of antibody-drug conjugates (ADCs)
- Serves as a click chemistry reagent
- Contains an alkyne group for reactions
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC)
- Reacts with azide group-containing molecules
- Features PEG5 structure
Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 250 MG
Propargyl-PEG5-Br is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This linker is ideal for researchers developing novel protein degradation therapeutics.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 1 G
Propargyl-PEG5-Br is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs and functions as a click chemistry reagent. It contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Enables synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
- Supports development of PROTACs for target protein degradation
Medchemexpress LLC Propargyl-PEG4-Br | 1308299-09-3 | 97.0% | 250 MG
Propargyl-PEG4-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It also functions as a non-cleavable ADC linker for antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, featuring an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules.
- PEG-based PROTAC linker
- Non-cleavable ADC linker
- Click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition
Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 100 MG
Propargyl-PEG5-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Sigma Aldrich 2-Phenylbenzimidazole
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Sigma Aldrich 2-BROMO-3-CHLOROPYRIDINE-4-BORONIC ACID
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Sigma Aldrich 4-(4-Biphenyl)-2-(3-pyridyl)-thiazole
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Sigma Aldrich 3-Ethynylpyridine
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Sigma Aldrich Propargylamine
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Sigma Aldrich Propargyl alcohol
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