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Filtered Search Results
Aobchem AOBCHEM
5000861965 2 3-DIFLUORO-5- TRIFLUOROMETHY
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Ambeed AMBEED
5000868379 26-DIBROMO-4-TRIFLUOROMETH 1GR
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Ambeed AMBEED
5000866613 3-CHLORO-4-TRIFLUOROMETHYL 1GR
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Ambeed AMBEED
5000867604 22-DIFLUOROETHYL 4-METHYLB 5GR
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Ambeed AMBEED
5000869321 7-TETRADECENE 1GR
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Selleck Chemical LLC CY-09
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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CY-09 is a specific NLRP3 inflammasome inhibitor that directly targeted NLRP3 itself It is tested against the five major cytochrome P450 enzymes 1A2 2C9 2C19 2D6 and 3A4 with half maximal inhibitory concentration (IC50) values of 18 9 8 18 50 50 and 26 0 M respectively
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Ambeed AMBEED
5000869467 1-DIFLUOROMETHYL-4-IODO-1H 1GR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed AMBEED
5000869137 11133-PENTAMETHYL-3-OCTYLD 1GR
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000430450 3- TRIFLUOROMETHYL C 50G
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Medchemexpress LLC Cyclo(RLsKDK) TFA | 99.66% | 841.88 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cyclo(RLsKDK) TFA is a specific metalloproteinase ADAM8 inhibitor (IC50 182 nM) with potential applications in inflammatory diseases and cancer. It promotes ADAM8 activation and CD23 shedding in vitro, and significantly reduces tumor load and improves survival in pancreatic ductal adenocarcinoma (PDAC) mouse models.
- Specific inhibitor of metalloproteinase ADAM8
- Applications in inflammatory diseases and cancer
- Promotes ADAM8 activation and CD23 shedding
- Increases activity of pro-ADAM8
- Promotes growth of Panc1_ctrl and Panc1_A8 cells
- Causes ERK1/2 phosphorylation
- Reduces tumor load in mouse models
- Improves survival in PDAC mice
- Reduces soluble ADAM8 (sADAM8) content
- Decreases pERK1/2 activation and PDAC metastasis
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem AOBCHEM
5000865616 2-CHLORO-4- TRIFLUOROMETHYL BE
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Medchemexpress LLC 3-(3-Trifluoromethylphenyl)propanol | 78573-45-2 | C10H11F3O | 100 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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3-(3-Trifluoromethylphenyl)propanol is a drug intermediate used for the synthesis of various active compounds. It is stable under recommended storage conditions and has a molecular weight of 204.19.
- Used as a drug intermediate
- Stable under recommended storage conditions
- Suitable for laboratory chemicals and manufacture of substances
- For research use only
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eMolecules 344591-91-9 | 3-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-5-YL-5-BORONIC ACID | AstaTech | MFCD08701785 | 193.920 | C5H6BF3N2O2 | 95.000 | Cn1nc(cc1B(O)O)C(F)(F)F | 5g | 282983436
3-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-5-YL-5-BORONIC ACID | AstaTech | 344591-91-9 | MFCD08701785 | 193.920 | C5H6BF3N2O2 | 95.000 | Cn1nc(cc1B(O)O)C(F)(F)F | 5g | 282983436
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem AOBCHEM
5000873399 1- 3-ETHOXY-5- TRIFLUOROMETHYL
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Ambeed AMBEED
5000884397 2-BROMO-4-TRIFLUOROMETHY 10G
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