Organofluorides

Selleck Chemical LLC PYR-41

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PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1 with no activity at E2 PYR-41 induce apoptosis

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Apexbio Technology LLC AZ 628 878739-06-1 10mg

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AZ 628 (CAS 878739-06-1) is a potent inhibitor of RAF kinases targeting BRAF c-RAF-1 and the mutant BRAFV600E with reported IC50 values of 105 nM 34 nM and 29 nM respectively The compound exerts its activity by occupying the ATP-binding site of RAF kinases thereby blocking CRAF activation it also affects other tyrosine kinases such as DDR2 VEGFR2 Lyn Flt1 and FMS AZ 628 disrupts the RAS-RAF-MEK-ERK (MAPK) signaling cascade influencing cellular responses including proliferation and apoptosis In preclinical studies AZ 628 inhibits growth and induces apoptosis in BRAF V600E-mutant melanoma and colorectal cancer cell lines and demonstrates anti-angiogenic effects via VEGFR2 inhibition

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eMolecules​ 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine dihydrochloride | 120298-11-5 | MFCD09997861 | 1g

J & W PharmLab LLC | 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine dihydrochloride | 1g | 282990145 | 65R0014S | 96.000 | 120298-11-5 | MFCD09997861 | 304.140 | C10H14Cl2F3N3

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Medchemexpress LLC MEDCHEMEXPRESS LLC

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5000398456 CYCLO HIS-PHE TFA 10MG

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Ambeed Formylhydrazine

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Formylhydrazine, 624-84-0, 98%

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eMolecules​ EMOLECULES INC

5000190288 1-DIFLUOROMETHYL-4-IOD 250MG

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Medchemexpress LLC Benzothiazole-5-boronic acid pinacol ester | 1073354-91-2 | MFCD09260439 | >98.0% | 261.15 g·mol⁻¹ | C13H16BNO2S | 25 G

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Benzothiazole-5-boronic acid pinacol ester is a boronate reagent used as the boronate coupling partner in Suzuki cross-coupling reactions. It is intended for research use as a synthetic building block in organic chemistry and offers a defined molecular composition and high chemical purity.

• Suitable boronate reagent for Suzuki cross-coupling reactions.
• High purity: ≥98.0%.
• Molecular formula C13H16BNO2S, molecular weight 261.15 g·mol⁻¹.
• Pinacol boronate ester offers stability under common handling conditions.
• Supplied for research and synthetic applications.

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eMolecules​ 2-Bromo-3,4,5,6-tetrafluoronitrobenzene | 5580-83-6 | MFCD22683869 | 1g

WuXi ChemSupply | 2-Bromo-3,4,5,6-tetrafluoronitrobenzene | 1g | 599169724 | LN02156925 | 95.000 | 5580-83-6 | MFCD22683869 | 273.969 | C6BrF4NO2

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Medchemexpress LLC 5-(trifluoromethyl)uracil | 54-20-6 | MFCD00006024 | 99.6% | 180.09 g/mol | C5H3F3N2O2 | 10 G

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5-(Trifluoromethyl)uracil is a fluorinated uracil derivative supplied as a solid reagent for life-science research and synthetic chemistry. It is used as a building block and research tool in nucleic acid chemistry and related studies. CAS 54-20-6; molecular formula C5H3F3N2O2; molecular weight ~180.09 g/mol.

• High purity suitable for research applications.
• Solid form simplifies storage and handling.
• Useful as a building block for nucleic acid analogue synthesis.
• Characterized by CAS number and molecular formula for traceability.
• Available in multiple package sizes to support different workflows.

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eMolecules​ DICHLORO 1 3-BIS2 6-DI- 100MG

5000190938 DICHLORO 1 3-BIS2 6-DI- 100MG

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eMolecules​ 3-BROMO-5-TRIFLUOROMETH 250MG

5000190980 3-BROMO-5-TRIFLUOROMETH 250MG

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Ambeed Formylhydrazine

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Formylhydrazine, 624-84-0, 98%