AdipoGen Difluoromethyl phenyl sulfone
Chemical. CAS 1535-65-5. Formula C7H6F2O2S. MW 192.2. Synthetic. Building block for synthesis. Has been used for nucleophilic difluorophenylsulfonylmethylation of carbonyls, reductive silylation and the preparation of trifluoro- and difluoromethylsilanes, fluoroalkylation/chloroalkylation of alpha,beta-enones, arynes, acetylenic ketones and other Michael acceptors and difluoromethylation of primary alkyl halides . It is also used in preparation of alpha-difluoromethyl amines, anti-difluoropropanediols, beta-difluoromethylated and beta-difluoromethylenated alcohols and amines, difluoroalkenes, difluoromethyl alcohol derivatives and fluoromethylated vicinal ethylenediamines.