Cyano-myracrylamide is a small-molecule inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 (zDHHC20) with a reported IC50 of 1.35 μM. It has been shown to inhibit S-acylation of several substrate proteins in cell-based assays and is supplied as a white to off-white solid for laboratory research. Molecular formula C19H34N2O; molecular weight 306.49 g/mol.