Metal Aryls
![Medchemexpress LLC 5-(hexahydropyrrolo[1,2-a]pyrazine-2-carbonyl)-4-chloro-2-fluoro-N-(2-fluorophenyl)benzenesulfonamide | 1235560-28-7 | MFCD29924737 | 99.3% | 457.48 g/mol | C20H20ClF2N3O3S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000294773.png-250.jpg)
Medchemexpress LLC 5-(hexahydropyrrolo[1,2-a]pyrazine-2-carbonyl)-4-chloro-2-fluoro-N-(2-fluorophenyl)benzenesulfonamide | 1235560-28-7 | MFCD29924737 | 99.3% | 457.48 g/mol | C20H20ClF2N3O3S | 10 MG
ABT-639 is a peripherally acting, selective T-type Ca2+ (CaV3.2) calcium channel blocker supplied as a research reagent. It has been investigated for analgesic and antihyperalgesic activity in preclinical and clinical studies and is provided as a high-purity solid for laboratory use.
- Peripherally acting T-type Ca2+ channel blocker.
- Selective for CaV3.2 T-type channels.
- High purity suitable for research applications.
- Supplied as a solid, convenient for formulation and dosing.
- Intended for in vitro and in vivo research use; not for human use.
Aobchem 2-Trifluoromethylpyridine-5-boronic acid pinacol ester | ≥97% | CAS 1218790-39-6 | C12H15BF3NO2 | 250mg
2-Trifluoromethylpyridine-5-boronic acid pinacol ester | ≥97% | CAS 1218790-39-6 | C12H15BF3NO2 | 250mg
Aobchem 3-Fluoro-2-(tributylstannyl)pyridine | ≥97% | CAS 573675-60-2 | C17H30FNSn | 5g
3-Fluoro-2-(tributylstannyl)pyridine | ≥97% | CAS 573675-60-2 | C17H30FNSn | 5g
Medchemexpress LLC ABT-639 | 1235560-28-7 | 99.3% | 455.91 | 50 MG
ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. It is used for research purposes only and not sold to patients. It effectively reduces nociceptive and neuropathic pain in rats.
- Blocks recombinant human T-type (Cav3.2) Ca2+ channels in a voltage-dependent fashion.
- Attenuates low voltage-activated (LVA) currents in rat DRG neurons.
- Significantly less active at other Ca2+ channels (e.g., Cav1.2 and Cav2.2).
- High oral bioavailability (%f=73) in rodents.
- Low protein binding (88.9%) in rodents.
- Low brain:plasma ratio (0.05:1) in rodents.
- Produces dose-dependent antinociception in a rat model of knee joint pain.
- Increases tactile allodynia thresholds in multiple models of neuropathic pain.
- Does not significantly alter hemodynamic or psychomotor function at higher doses.
Medchemexpress LLC Obidoxime dichloride | 114-90-9 | 96.60% | 359.21 | 5 MG
Obidoxime dichloride is a non-full spectrum oxime agent used as an antidote for organophosphate nerve agent poisoning. It functions by reactivating sarin-inhibited acetylcholinesterase (AChE) and has been shown to reduce the acute toxicity of sarin.
- Reactivates sarin-inhibited acetylcholinesterase (AChE)
- Reduces acute toxicity of sarin
- Available in solid form
- Off-white to light yellow appearance
- Soluble in water and DMSO
- Can be stored at -20°C, protected from light and under nitrogen
Aobchem 1 1-Dimethylethyl 4-(3 4-dichlorobenzoyl)-1-piperidinecarboxylate | 95% | CAS 269731-79-5 | C17H21Cl2NO3 | 250mg
1 1-Dimethylethyl 4-(3 4-dichlorobenzoyl)-1-piperidinecarboxylate | 95% | CAS 269731-79-5 | C17H21Cl2NO3 | 250mg
Aobchem 5-Chloroisophthaloyl dichloride | 95% | CAS 2855-02-9 | C8H3Cl3O2 | 1g
5-Chloroisophthaloyl dichloride | 95% | CAS 2855-02-9 | C8H3Cl3O2 | 1g
eMolecules Ambeed Methyl 3-amino-5 6-dichloro-2-pyrazinecarboxylate 50mg 521393976 A108171 0 000 1458-18-0 MFCD00010431 222 030 C6H5Cl2N3O2
Ambeed Methyl 3-amino-5 6-dichloro-2-pyrazinecarboxylate 50mg 521393976 A108171 0 000 1458-18-0 MFCD00010431 222 030 C6H5Cl2N3O2
Medchemexpress LLC ABT-639 | 1235560-28-7 | 99.3% | 455.91 | 5 MG
ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. It is for research use only and not sold to patients.
- Novel, peripherally acting, selective T-type Ca2+ channel blocker.
- Blocks recombinant human T-type (Cav3.2) Ca2+ channels (IC50=2 μM).
- Attenuates low voltage-activated (LVA) currents in rat DRG neurons (IC50=8 μM).
- Less active at other Ca2+ channels (e.g., Cav1.2, Cav2.2) (IC50>30 mM).
- High oral bioavailability (%F=73), low protein binding (88.9%), low brain:plasma ratio (0.05:1) in rodents.
- Produces dose-dependent antinociception in rat model of knee joint pain (ED50=2 mg/kg, p.o.).
- Increases tactile allodynia thresholds in multiple models of neuropathic pain (10-100 mg/kg, p.o.).
- Does not attenuate hyperalgesia in inflammatory pain models.
- Does not significantly alter hemodynamic or psychomotor function at higher doses (e.g., 100-300 mg/kg).
eMolecules 131747-43-8 | 2-(Trifluoromethyl)pyridine-3-carboxylic Acid | Accela ChemBio (ASD) | MFCD01862052 | 191.109 | C7H4F3NO2 | 97.000 | OC(=O)c1cccnc1C(F)(F)F | 1g | 444758920
2-(Trifluoromethyl)pyridine-3-carboxylic Acid | Accela ChemBio (ASD) | 131747-43-8 | MFCD01862052 | 191.109 | C7H4F3NO2 | 97.000 | OC(=O)c1cccnc1C(F)(F)F | 1g | 444758920
Frontier Specialty Chemicals 100G 2-(TRIBUTYLSTANNYL)PYRIDI
100g 2-(tributylstannyl)pyridi. 17997-47-6
eMolecules 131747-43-8 | 2-(Trifluoromethyl)pyridine-3-carboxylic Acid | Accela ChemBio (ASD) | MFCD01862052 | 191.109 | C7H4F3NO2 | 97.000 | OC(=O)c1cccnc1C(F)(F)F | 5g | 444758918
2-(Trifluoromethyl)pyridine-3-carboxylic Acid | Accela ChemBio (ASD) | 131747-43-8 | MFCD01862052 | 191.109 | C7H4F3NO2 | 97.000 | OC(=O)c1cccnc1C(F)(F)F | 5g | 444758918
Aobchem 1 1-Dimethylethyl 3-(3 4-dichlorophenyl)-3-hydroxy-1-azetidinecarboxylate | ≥95% | CAS 1447464-06-3 | C14H17Cl2NO3 | 500mg
1 1-Dimethylethyl 3-(3 4-dichlorophenyl)-3-hydroxy-1-azetidinecarboxylate | ≥95% | CAS 1447464-06-3 | C14H17Cl2NO3 | 500mg