Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate | 252881-73-5 | 303.3547 g/mol | C13H25N3O5 | 50 MG
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N3-PEG3-CH2CH2-Boc is an azido-terminated PEG3 linker with a tert-butyl (Boc) protected carboxylic acid end, used as a cleavable PEG-based linker in antibody-drug conjugate and PROTAC synthesis, and as an azide reagent for click chemistry.
- Azide-terminated PEG3 linker suitable for click chemistry.
- tert-Butyl (Boc) protected carboxyl end for orthogonal deprotection.
- Used in ADC and PROTAC linker assembly.
- Available as a small pre-weighed laboratory pack for synthetic use.
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Medchemexpress LLC Biotin-PEG3-SS-azide | 2866429-93-6 | 99.6% | 692.91 | C27H48N8O7S3 | 10 MG
Biotin-PEG3-SS-azide is a cleavable three-unit polyethylene glycol linker bearing a biotin group and a terminal azide, designed for conjugation chemistry in research applications. It is suitable for click chemistry reactions and as a cleavable linker in the synthesis of antibody-drug conjugates.
- Cleavable disulfide linker provides intracellular release.
- Azide functionality enables CuAAC and strain-promoted cycloaddition.
- PEG3 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable conjugation results.
- Soluble in DMSO at high concentration for in vitro use.
- Recommended storage at low temperature and protection from light to preserve stability.
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Medchemexpress LLC 3- TRIMETHOXYSILYL P 25G
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5000206616 3- TRIMETHOXYSILYL P 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
5000422941 PEPINH-TRIF TFA 10MG
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Medchemexpress LLC Ak-778-xxmu | 1227045-76-2 | 100.0% | C22H17ClN2O3 | 10MG
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AK-778-XXMU is a small-molecule antagonist of DNA binding inhibitor 2 (ID2) used for research applications. It binds ID2 with a reported KD of 129 nM, inhibits glioma cell migration and invasion, induces apoptosis, and modulates ID2-KDR signaling to affect VEGFA, MMP2/9, and PTEN.
- Potent ID2 binding (KD 129 nM).
- Demonstrated inhibition of glioma cell migration and invasion.
- Induces apoptosis in glioma cell lines.
- Modulates angiogenesis and invasion-related signaling pathways.
- High chemical purity (99.96%).
- Soluble in DMSO at 100 mg/mL; ultrasonic may be required.
- Stable as a powder at -20°C for long-term storage.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000353829 METHYLTETRAZINE-AMID 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000353864 M-PEG5-BR 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000353546 AZIDO-PEG3-C-BOC 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000358699 5-BROMO-2-TRIFLUOROM 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000341716 THP-PEG5-OH 25MG
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Apexbio Technology LLC PS-1145 431898-65-6 5mg
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PS-1145 (CAS 431898-65-6) is a selective inhibitor of I B kinase (IKK) with an IC50 of 88 nM IKK is a critical component of the upstream NF- B signaling pathway regulating cellular responses to inflammation In vitro studies have demonstrated that PS-1145 blocks TNF -induced NF- B activation in multiple myeloma (MM) cells in a dose- and time-dependent manner increases I B protein levels suppresses IL-6-mediated anti-apoptotic effects and inhibits expression of ICAM-1 Additionally PS-1145 reduces IL-6 secretion from bone marrow stromal cells (BMSCs) and partially limits MM cell proliferation In vivo PS-1145 has been shown to induce apoptosis in DMBA-induced skin tumors in rats by inhibiting NF- B and VEGF activity The compound remains in the preclinical research stage
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Medchemexpress LLC D-ribofuranose-13C5 | 97.0% | 155.09 | 13C5H10O5 | 10mg
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D-Ribofuranose-13C5 (D-Ribose-13C5) is the 13C-labeled D-Ribofuranose (HY-113375) D-Ribofuranose (D-Ribose) is an endogenous metabolite present in Cerebrospinal Fluid that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency and Medium Chain Acyl Co A Dehydrogenase Deficiency[1][2]
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000357374 AZIDO-PEG5-TRIETHOXY 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000357217 TRI AMINO-PEG3-AMIDE 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
5000422369 PEPINH-TRIF TFA 5MG
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