Organo-Metalloid Compounds
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- (251)
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Filtered Search Results
Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 50 MG
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BM-PEG3 is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound has a molecular weight of 352.34 and a chemical formula of C16H20N2O7, appearing as a white to light yellow solid. It is soluble in DMSO, with recommendations for proper storage and handling for both powder and solvent forms.
- It is a polyethylene glycol-based linker.
- It is used in the synthesis of proteolysis-targeting chimeras.
- It aids in the degradation of target proteins.
- It has a high purity of 98.0%.
- It is available as a white to light yellow solid.
- It can be dissolved in DMSO for in vitro experiments.
- It can be formulated for in vivo studies using specific co-solvents like DMSO and corn oil.
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Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 5 G
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is for research use only.
- This product is a PEG-based PROTAC linker.
- PROTACs are composed of two different ligands linked together; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein.
- PROTACs function by utilizing the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
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Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | 99.9% | 368.47 | 250 MG
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BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity: 99.94%
- Molecular weight: 368.47
- Chemical formula: C19H32N2O5
- CAS number: 1841134-72-2
- Appearance: Colorless to light yellow liquid
- Density: 1.14±0.1 g/cm3
- Used in PROTAC synthesis
- Contains a BCN group for SPAAC reactions
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Medchemexpress LLC N-Boc-PEG5-bromide | 1392499-32-9 | MFCD31536756 | 98.0% | 400.31 g·mol⁻¹ | C15H30BrNO6 | 100 MG
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N-Boc-PEG5-bromide is a Boc-protected polyethylene glycol (PEG) linker bearing a terminal bromide functional group. It is used as a reactive building block in the synthesis of antibody-drug conjugates (ADCs) and PROTACs to introduce a five-unit PEG spacer that improves solubility and provides a reactive handle for conjugation chemistry.
- Boc-protected amine allows selective deprotection under acidic conditions.
- Terminal bromide enables alkylation and nucleophilic substitution reactions.
- Five-unit PEG spacer improves aqueous solubility and linker flexibility.
- High purity suitable for research applications (98.0%).
- Supplied as a solid and available in small-scale pack sizes including 100 MG.
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Medchemexpress LLC Nh2-peg3 (protac linker 35) | 6338-55-2 | MFCD07367495 | 149.19 | 1 G
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NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. This compound can be used in the synthesis of the PROTAC (β-NF-JQ1).
- PROTAC linker
- Polyethylene glycol (PEG) linker
- Suitable for synthesis of PROTAC (β-NF-JQ1)
- Colorless to light yellow liquid
- Purity: 99.87%
- Molecular weight: 149.19
- CAS number: 6338-55-2
- Density: 1.0773 g/cm3
- Solubility in DMSO: 100 mg/mL
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 10 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Utilized in the synthesis of PROTACs.
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
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Medchemexpress LLC BCN-EXO-PEG3-NH2 50 mg
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BCN-EXO-PEG3-NH2 50MG
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Medchemexpress LLC BIOTIN-PEG3-BENZOPHE 5 mg
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BIOTIN-PEG3-BENZOPHE 5MG
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Medchemexpress LLC AMINOOXY-PEG3-C2-THI 25 mg
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AMINOOXY-PEG3-C2-THI 25MG
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Medchemexpress LLC BCN-EXO-PEG3-NH2 25 mg
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BCN-EXO-PEG3-NH2 25MG
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Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 1 G
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Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker designed for the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- Suitable for PROTAC synthesis
- Molecular weight: 308.37
- Targeted for PROTAC linkers pathway
- Recommended storage: 4°C, sealed, away from moisture and light (solid); -80°C for 6 months or -20°C for 1 month (in solvent)
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | Ambeed | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 25g | 562293042
NH2-PEG3-C2-Boc | Ambeed | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 25g | 562293042
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eMolecules 252881-74-6 | H2N-PEG3-CH2CH2COOtBu | Acrotein ChemBio Inc. | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 5g | 487536523
H2N-PEG3-CH2CH2COOtBu | Acrotein ChemBio Inc. | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 5g | 487536523
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N-(Azido-PEG2)-N-bis(PEG4-Boc) | 2112731-81-2 | C36H70N4O14 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains an azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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(C)Oc1c(Cl)ccc(B(O)O)c1F | 1g | 117524740](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502191757.JPG-250.jpg)
eMolecules 1256354-94-5 | 3-(t-Butyldimethylsilyloxy)-4-chloro-2-fluorophenylboronic acid | Combi-Blocks | MFCD17015761 | 304.620 | C12H19BClFO3Si | 95.000 | CC(C)(C)[Si](C)(C)Oc1c(Cl)ccc(B(O)O)c1F | 1g | 117524740
3-(t-Butyldimethylsilyloxy)-4-chloro-2-fluorophenylboronic acid | Combi-Blocks | 1256354-94-5 | MFCD17015761 | 304.620 | C12H19BClFO3Si | 95.000 | CC(C)(C)[Si](C)(C)Oc1c(Cl)ccc(B(O)O)c1F | 1g | 117524740
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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