Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 1-phenyl-2,5,8,11,14-pentaoxahexadecan-16-ol | 57671-28-0 | MFCD06797154 | 98.6% | 328.40 g/mol | C17H28O6 | 1 G
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BnO-PEG5-OH is a benzyl-terminated PEG5 primary alcohol used as a flexible linker in PROTAC synthesis. It provides a short polyethylene glycol spacer with a terminal benzyl-protected alcohol functionality that can be modified for conjugation to ligands and linkers.
- Provides a PEG5 spacer for flexibility and improved solubility.
- Benzyl-protected terminal alcohol enables selective deprotection and further functionalization.
- High purity suitable for medicinal chemistry and research use.
- Characterized by certificate of analysis, 1H NMR, and RP-HPLC documentation.
- Available in small pack sizes for synthetic applications.
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Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 100 MG
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TBDMS-PEG3-OH is a tert-butyldimethylsilyl-protected PEG3-derived alcohol supplied for research use. It is used as a versatile linker and building block in medicinal chemistry, PROTAC synthesis, PEGylation, and drug-delivery conjugation, and is provided as a high-purity liquid suitable for synthetic applications.
- High purity (≥98.0%).
- Molecular weight 264.43 g/mol.
- Molecular formula C12H28O4Si.
- Suitable for linker and PEGylation chemistry.
- Available in small-scale packages for research (100 MG).
- For research use only; not for human use.
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Medchemexpress LLC HO-PEG3-(CH2)6-Cl | 1355955-95-1 | 95.0% | 268.78 | C12H25ClO4 | 5 MG
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HO-PEG3-(CH2)6-Cl is a PEG-based PROTAC linker containing a hydroxy-terminated PEG3 spacer attached to a six-carbon chain bearing a terminal chloride. It is intended as a functionalized spacer for assembling PROTACs and other ligand-linker conjugates and is supplied for research use only.
- Hydroxy-terminated PEG3 linker for flexible spacer design.
- Six-carbon chloroalkyl handle enables haloalkane conjugation chemistry.
- Suitable for assembling PROTACs and ligand-linker constructs.
- Available in small research-scale quantities, such as 5 mg.
- Molecular formula C12H25ClO4 and molecular weight 268.78.
- For research use only; not for human or clinical use.
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 100 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand that can be used for the synthesis of PROTACs. It is intended for research use only and is not for sale to patients. Its appearance is a solid, ranging from white to light yellow in color.
- VHL ligand
- Can be used for the synthesis of PROTACs
- Intended for research use only
- Solid, white to light yellow appearance
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Medchemexpress LLC Perfluorophenyl 3-(2-(2-(2-(1,3-dioxoisoindolin-2-yloxy)ethoxy)ethoxy)ethoxy)propanoate | 2101206-87-3 | >96.0% | 533.4 g/mol | C23H20F5NO8 | 10 MG
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NHPI-PEG3-C2-Pfp ester is a noncleavable, trifunctional 3-unit polyethylene glycol (PEG) linker bearing an N-hydroxyphthalimide (NHPI) group and a perfluorophenyl (Pfp) activated ester. It is used for bioconjugation and in the synthesis of antibody-drug conjugates (ADCs). Intended for research use only.
- Noncleavable 3-unit PEG linker
- NHPI functional group for site-specific conjugation
- Perfluorophenyl activated ester for amine coupling
- Molecular weight about 533.4 g/mol; formula C23H20F5NO8
- Purity greater than 96%
- Intended for research use only, not for human or animal use
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Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 25 G
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects two ligands in PROTACs
- Facilitates protein degradation via ubiquitin-proteasome system
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Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 10 G
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Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- Ligands for an E3 ubiquitin ligase and a target protein
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eMolecules 134179-38-7 | Amino-PEG3-C2-Azido | Medchem Express | MFCD00269874 | 218.257 | C8H18N4O3 | 98.000 | NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 746319562
Amino-PEG3-C2-Azido | Medchem Express | 134179-38-7 | MFCD00269874 | 218.257 | C8H18N4O3 | 98.000 | NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 746319562
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Medchemexpress LLC 4,7,10,13-tetraoxatetradecanoic acid | 67319-28-2 | 97.0% | 236.26 | C10H20O6 | 1 G
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m-PEG3-CH2CH2COOH is a monomethyl-terminated PEG3 linker bearing a terminal carboxylic acid, used as a non-cleavable linker in antibody-drug conjugate and PROTAC synthesis. It is supplied as a colorless to light yellow liquid with a high NMR purity and defined molecular properties.
- Monomethyl-terminated PEG3 linker
- Terminal carboxylic acid functionality for conjugation
- Suitable for ADC and PROTAC synthesis
- Colorless to light yellow liquid form
- 97.0% purity (NMR)
- Molecular weight 236.26; formula C10H20O6
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Medchemexpress LLC Pc biotin-PEG3-azide | 1937270-46-6 | 97.8% | 825.93 g/mol | C35H55N9O12S | 10 MG
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PC Biotin-PEG3-azide is a cleavable three-unit polyethylene glycol (PEG3) biotinylated azide linker used for bioconjugation and the synthesis of antibody-drug conjugates. It contains an azide functional group for click chemistry and reacts in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Cleavable three-unit PEG linker.
- Contains an azide functional group for click chemistry.
- Suits copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- High research-grade purity.
- Available in small-scale quantities for conjugation workflows.
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Medchemexpress LLC NH2-PEG3 (PROTAC Linker 35) | 6338-55-2 | 149.19 | 25 G
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NH2-PEG3 (PROTAC Linker 35) is a polyethylene glycol (PEG) linker used in the synthesis of PROTACs such as β-NF-JQ1. This chemical is intended for research use only.
- PROTAC linker
- Polyethylene glycol linker
- Used in the synthesis of PROTAC (β-NF-JQ1)
- Purity: 99.9%
- Molecular weight: 149.19
- Formula: C6H15NO3
- Appearance: Liquid (density: 1.0773 g/cm3)
- Color: Colorless to light yellow
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC T-Boc-aminooxy-PEG5-azide | 2250216-95-4 | 95.0% | C17H34N4O8 | 50 MG
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t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group for reactions
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Bis-aminooxy-PEG3 | 98627-70-4 | 98.0% | C8H20N2O5 | 50 MG
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Bis-aminooxy-PEG3 (CAS: 98627-70-4) is a chemical compound with the molecular formula C8H20N2O5 and a molecular weight of 224.25. It is typically a colorless to light yellow liquid. This product is intended for research use only.
- Purity of 98.0% by NMR
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Appearance is a colorless to light yellow liquid
- Chemical structure consistent with 1H NMR and MS analysis
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Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.35% | 508.56 | 50 MG
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It features a DBCO group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Non-cleavable 3 unit PEG ADC linker.
- Used in the synthesis of antibody-drug conjugates (ADCs).
- Contains a DBCO group.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
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Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | C28H36N8O10 | 1 MG
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Folate-PEG3-C2-acid is a specialized acid fragment derived from Folate-PEG3-NHS ester, designed as a PEG-type PROTAC linker. This compound is crucial for the synthesis of PROTAC (PROteolysis TArgeting Chimera) molecules, which are heterobifunctional molecules that induce the degradation of target proteins. Its molecular structure facilitates the creation of complex PROTACs, enabling advanced research in targeted protein degradation.
- PEG-type PROTAC linker
- Acid fragment of Folate-PEG3-NHS ester
- Essential for synthesizing PROTAC molecules
- Purity of 97.56% ensures reliable experimental results
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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