Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 1 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
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Medchemexpress LLC DNP-PEG3-azide | 951671-87-7 | 99.2% | C14H20N6O7 | 500 MG
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DNP-PEG3-azide is a PEG-based PROTAC linker that functions as a click chemistry reagent due to its Azide group. It is utilized in the synthesis of PROTACs, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Reacts with alkyne-containing molecules
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Reacts with molecules possessing DBCO or BCN groups
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Medchemexpress LLC Boc-NH-PEG5-CH2CH2COOH | 1347750-78-0 | MFCD24539478 | ≥97.0% | 409.47 g/mol | C18H35NO9 | 250 MG
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Boc-NH-PEG5-CH2CH2COOH is a Boc-protected PEG5 linker terminating in a propionic acid functionality. It is used as a modular building block for assembling bifunctional molecules such as PROTACs, providing a hydrophilic, flexible spacer and a protected amine handle for selective deprotection and subsequent coupling reactions.
- Hydrophilic PEG5 spacer improves solubility and flexibility.
- Boc-protected amine allows controlled deprotection and functionalization.
- Terminal carboxylic acid enables straightforward coupling to ligands or linkers.
- Moderate molecular weight suitable for linker design without excessive bulk.
- Intended for use as a chemical building block in medicinal chemistry workflows.
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Medchemexpress LLC Azido-PEG3-propionic acid tert-butyl ester | 252881-73-5 | MFCD22201543 | ≥98.0% | 303.35 g/mol | C13H25N3O5 | 100 MG
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Azido-PEG3-propionic acid tert-butyl ester is an azide-functionalized, Boc-protected PEG3 linker for bioconjugation. It acts as a cleavable three-unit PEG spacer and an azide reagent for click chemistry, suitable for assembling antibody-drug conjugates and PROTACs.
- Azide-functionalized Boc-protected PEG3 linker.
- Cleavable three-unit PEG spacer for ADC and PROTAC synthesis.
- Suitable for CuAAC and SPAAC click chemistry.
- Purity ≥98.0%.
- Molecular weight 303.35 g/mol; formula C13H25N3O5.
- Appearance colorless to light yellow liquid; follow storage recommendations.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | ≥97.0% | 263.29 | C10H21N3O5 | 10 G
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Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker bearing a terminal azide and a terminal hydroxyl group. It functions as a non-cleavable, five-unit PEG spacer for bioconjugation and click chemistry applications.
- Contains azide (-N3) and terminal alcohol (-OH) functional groups.
- Water-soluble PEG linker suitable for click chemistry and PROTAC/ADC assembly.
- Molecular weight ~263.29 g/mol; formula C10H21N3O5.
- High purity, typically ≥97.0% by manufacturer specification.
- Available in multiple pack sizes, including 10 g.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 hydrochloride | 2446474-09-3 | 96.6% | 100 MG
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Pomalidomide-PEG3-C2-NH2 hydrochloride is an E3 ligase ligand and linker conjugate. It is utilized in PROTAC technology for designing and developing novel targeted inhibitors. The E3 ligase ligand component, such as Pomalidomide, binds to a specific E3 ligase, while a linker connects it to a ligand that recognizes a targeted protein, a mechanism crucial for PROTAC activity.
- Functions as an E3 ligase ligand for Cereblon.
- Used in PROTAC technology.
- Aids in designing and developing novel targeted inhibitors.
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Medchemexpress LLC 5,8,11-trioxa-2-azatridecanoic acid, 13-hydroxy-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 25 MG
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BCN-PEG3-OH is a BCN-functionalized, 4-unit polyethylene glycol (PEG) linker and click-chemistry reagent used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis. It contains a bicyclo[6.1.0]non-4-yne (BCN) group that reacts via strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized molecules, enabling efficient bioconjugation.
- Non-cleavable 4-unit PEG linker for ADC synthesis.
- BCN group enables SPAAC click chemistry with azides.
- High purity (99.6% by LCMS).
- Light yellow oil appearance.
- Stored at -20°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC Bromoacetamido-PEG3-azide | 940005-81-2 | ≥97.0% | C10H19BrN4O4 | 25 MG
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Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- Facilitates selective degradation of target proteins through the intracellular ubiquitin-proteasome system
- Intended for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester | 2100306-76-9 | 95.0% | C30H54N6O11S | 50 MG
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N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, enabling specific reactions with other molecules. This product is intended for research use only.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group for specific reactions
- Enables copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC m-PEG5-NH2 | 5498-83-9 | MFCD00010996 | 99.0% | C11H25NO5 | 1 G
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m-PEG5-NH2 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs function by connecting two ligands-one for an E3 ubiquitin ligase and another for a target protein-to leverage the intracellular ubiquitin-proteasome system for selective protein degradation. The product has a purity of 99.02%.
- Peg-based protac linker
- Used in the synthesis of protacs
- Facilitates protein degradation via the ubiquitin-proteasome system
- High purity
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Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 5 MG
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Aminooxy-PEG3-azide is a bifunctional PEG linker containing an aminooxy group and an azide handle for oxime ligation and azide-alkyne click chemistry. It is supplied as a liquid and is used for ADC and PROTAC linker synthesis, and for general bioconjugation and small-molecule assembly.
- Bifunctional: aminooxy and azide reactive groups.
- Peg3 spacer provides hydrophilicity and flexibility.
- Suitable for oxime formation with carbonyls and CuAAC click reactions.
- Purity typically 95.0%.
- Stable when stored at -20°C; in solvent short-term storage at lower temperatures recommended.
- Available in small research quantities, such as 5 mg.
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Medchemexpress LLC Bis-PEG5-acid 1g | 439114-13-3 | 338.35 g/mol | C14H26O9 | 1 G
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Bis-PEG5-acid is a polyethylene glycol (PEG) linker bearing two terminal carboxylic acid groups, used as a hydrophilic spacer in PROTAC construction and bioconjugation chemistry. It facilitates coupling reactions and improves aqueous solubility for assembled molecules.
- Two terminal carboxylic acid groups enable standard amide coupling reactions.
- PEG5 spacer provides hydrophilicity and conformational flexibility.
- Molecular weight 338.35 g/mol and formula C14H26O9 for precise stoichiometry.
- Suitable for PROTAC synthesis and general linker applications in medicinal chemistry.
- Offered in research quantities including 1 g for small-scale synthesis.
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 1 MG
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(S,R,S)-AHPC-C2-PEG3-BCN is a VHL ligand used for the synthesis of PROTACs. This product is intended for research use only.
- VHL ligand
- Used for the synthesis of PROTACs
- For research use only
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Medchemexpress LLC PEG3-C4-OBn | 2381196-79-6 | 99.3% | 250 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of PROTAC SGK3 degrader-1, a potent SGK3 degrader based on PROTAC technology. This product is for research use only.
- Molecular weight: 296.40
- Formula: C17H28O4
- Appearance: Liquid (density: 1.031 g/cm³)
- Color: Colorless to light yellow
- Shipping: Room temperature in continental US
- Pure form storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- In vitro solubility: ≥ 100 mg/mL in DMSO
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Medchemexpress LLC N- Azido-PEG3 -N-bis | 500MG
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N- Azido-PEG3 -N-bis | 500MG
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