Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 2-(2-(2-Bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | 100 MG
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Br-PEG3-MS is a PEG-based PROTAC linker employed in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 572245281
Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 572245281
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Medchemexpress LLC O,O'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 100 MG
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This product, Bis-aminooxy-PEG3, is a PEG-based PROTAC linker. It has a molecular weight of 224.25 and appears as a colorless to light yellow liquid.
- Consistent with structure based on ¹H NMR spectrum
- Consistent with structure based on MS
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![Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202875.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G
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Hydroxy-PEG3-(CH2)2-Boc is a Boc-protected, hydroxy-terminated polyethylene glycol linker used as a building block in linker and PROTAC synthesis. Supplied as a white to off-white solid, it has a typical purity of 95.0% and a molecular weight of 278.34 g/mol (CAS 186020-66-6).
- Boc-protected hydroxy-terminated PEG3 linker for synthetic chemistry.
- Typical purity 95.0% by NMR.
- Molecular weight 278.34 g/mol.
- Chemical formula C13H26O6.
- Supplied as a 25 g package for laboratory research use only.
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Medchemexpress LLC Bis-PEG5-NHS ester | 756526-03-1 | 99.8% | 532.50 g/mol | C22H32N2O13 | 25 MG
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Bis-PEG5-NHS ester is a bifunctional PEG-based cleavable NHS-activated ester used for conjugation to primary amines in the synthesis of antibody-drug conjugates (ADCs), PROTACs, and other bioconjugates. Supplied as a solid for research use, it facilitates PEGylation and formation of cleavable linkers in medicinal chemistry and chemical biology workflows.
- Cleavable PEG5 NHS ester for selective amine conjugation.
- Suitable for ADC and PROTAC linker synthesis.
- High purity, suitable for synthetic applications.
- Molecular weight 532.50 g/mol, chemical formula C22H32N2O13.
- Available in small-scale research quantities, e.g. 25 MG.
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Medchemexpress LLC (E)-Cyclooct-2-en-1-yl (2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)carbamate | 98.4% | 344.45 | C17H32N2O5 | 10 MG
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TCO-PEG3-NH2 is a click-chemistry reagent composed of a trans-cyclooctene (TCO) group linked to a three-unit polyethylene glycol spacer terminating in a primary amine. It enables fast bioorthogonal inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine-functionalized partners and amine-mediated conjugation for site-specific labeling of biomolecules.
- Enables rapid iEDDA bioorthogonal chemistry for fast conjugation.
- Terminal primary amine allows amide bond formation with carboxyl groups.
- Three-unit PEG spacer improves aqueous solubility and reduces steric hindrance.
- Suitable for site-specific labeling and bioconjugation workflows.
- Typically supplied as a small solid quantity for laboratory use.
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![Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202514.png-250.jpg)
Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG
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BCN-PEG3-OH is a BCN-functionalized PEG linker intended for bioconjugation and antibody-drug conjugate (ADC) synthesis. The reagent contains a bicyclo[6.1.0]nonyne (BCN) group that reacts with azides via strain-promoted alkyne-azide cycloaddition (SPAAC), enabling copper-free click chemistry in aqueous conditions.
- Non-cleavable four-unit PEG linker suitable for ADC construction.
- Enables strain-promoted alkyne-azide cycloaddition with azide-functionalized molecules.
- High reported purity for reliable conjugation performance.
- Available in multiple pack sizes, including small research quantities.
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TARGETMOL CHEMICALS INC PS-1145 10MG
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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM. Purity 99.63%
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Aobchem AOBCHEM
5000955423 2-TRIMETHYLSILANYLTHIAZOLE 5G
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(c1ccccc1)c1ccccc1 | 1000g | 772451881](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482268.jpg-250.jpg)
eMolecules 58479-61-1 | tert-Butylchlorodiphenylsilane | Ochem Incorporation | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
tert-Butylchlorodiphenylsilane | Ochem Incorporation | 58479-61-1 | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
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Apexbio Technology LLC NVR 3-778 1445790-55-5 5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NVR 3-778 (CAS 1445790-55-5) is a small-molecule modulator targeting the hepatitis B virus (HBV) core protein It is designed to interfere with HBV capsid assembly thereby inhibiting viral genome encapsidation and replication NVR 3-778 exerts its biological activity primarily by disrupting capsid formation and reducing viral replication In in vitro studies NVR 3-778 demonstrates antiviral inhibition with a half-maximal inhibitory concentration (IC50) reported in the low micromolar range Based on these pharmacological properties NVR 3-778 holds research potential in the investigation of HBV biology and the development of alternative therapeutic approaches for chronic hepatitis B infection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 123266-59-1 | 5,7-Dibromo-2,3-dihydrobenzofuran | Combi-Blocks | MFCD00191427 | 277.943 | C8H6Br2O | 96.000 | Brc1cc2CCOc2c(Br)c1 | 1g | 232308718
5,7-Dibromo-2,3-dihydrobenzofuran | Combi-Blocks | 123266-59-1 | MFCD00191427 | 277.943 | C8H6Br2O | 96.000 | Brc1cc2CCOc2c(Br)c1 | 1g | 232308718
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC PS-1145
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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PS-1145 is a specific IKK inhibitor with IC50 of 88 nM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC NVR 3-778 1445790-55-5 1mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
NVR 3-778 (CAS 1445790-55-5) is a small-molecule modulator targeting the hepatitis B virus (HBV) core protein It is designed to interfere with HBV capsid assembly thereby inhibiting viral genome encapsidation and replication NVR 3-778 exerts its biological activity primarily by disrupting capsid formation and reducing viral replication In in vitro studies NVR 3-778 demonstrates antiviral inhibition with a half-maximal inhibitory concentration (IC50) reported in the low micromolar range Based on these pharmacological properties NVR 3-778 holds research potential in the investigation of HBV biology and the development of alternative therapeutic approaches for chronic hepatitis B infection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC PS-1145 431898-65-6 5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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PS-1145 (CAS 431898-65-6) is a selective inhibitor of I B kinase (IKK) with an IC50 of 88 nM IKK is a critical component of the upstream NF- B signaling pathway regulating cellular responses to inflammation In vitro studies have demonstrated that PS-1145 blocks TNF -induced NF- B activation in multiple myeloma (MM) cells in a dose- and time-dependent manner increases I B protein levels suppresses IL-6-mediated anti-apoptotic effects and inhibits expression of ICAM-1 Additionally PS-1145 reduces IL-6 secretion from bone marrow stromal cells (BMSCs) and partially limits MM cell proliferation In vivo PS-1145 has been shown to induce apoptosis in DMBA-induced skin tumors in rats by inhibiting NF- B and VEGF activity The compound remains in the preclinical research stage
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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