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Filtered Search Results
Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | 99.5% | 25 MG
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Calcein tetraethyl ester is a fluorescent dye utilized in biology for evaluating cell viability and facilitating short-term cellular labeling. Its ability to permeate cellular membranes allows for transport into live cells.
- Fluorescent dye for biological applications
- Enables cell viability testing
- Suitable for short-term cell labeling
- Permeates live cell membranes
- Useful in cell staining analysis
- Applied in in vivo imaging fluorescence
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Medchemexpress LLC 2,5,8,11,14-pentaoxahexadecan-16-ol, 1-phenyl | 57671-28-0 | MFCD06797154 | 98.6% | 328.40 g/mol | C17H28O6 | 5 G
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BnO-PEG5-OH is a benzyl-protected PEG5 primary alcohol used as a short spacer or linker building block in PROTAC and conjugation chemistries. It provides a PEG chain with a terminal hydroxyl group masked by a benzyl protecting group, allowing selective deprotection and downstream functionalization.
- Provides a short polyethylene glycol spacer for linker design
- Contains a benzyl-protected terminal hydroxyl for selective deprotection
- Suitable for building block use in PROTAC and bioconjugate synthesis
- Available in multiple pack sizes for small-scale synthesis
- Offers high reported purity for synthetic applications
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Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 100 MG
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Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and alkyl/ether-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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Medchemexpress LLC Azide-PEG3-tos | 178685-33-1 | 329.37 g/mol | C13H19N3O5S | 250 MG
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Azide-PEG3-Tos is a heterobifunctional PEG linker containing an azide functional group for click chemistry. It acts as a non-cleavable, three-unit PEG linker used in the synthesis of PROTACs and antibody-drug conjugates, and participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions.
- Heterobifunctional PEG linker with azide group.
- Molecular weight 329.37 g/mol.
- Chemical formula C13H19N3O5S.
- CAS number 178685-33-1.
- Available in 250 MG packaging; other sizes available.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Applications: PROTAC synthesis, ADC construction, click chemistry.
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Medchemexpress LLC Bis-PEG5-PFP ester | 1334177-78-4 | 100 MG
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Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Contains two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase; the other targets the protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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eMolecules 581065-94-3 | Tos-PEG5 t-butyl ester | Abosyn Chemicals Inc. | MFCD22574810 | 476.580 | C22H36O9S | 0.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 5g | 875323786
Tos-PEG5 t-butyl ester | Abosyn Chemicals Inc. | 581065-94-3 | MFCD22574810 | 476.580 | C22H36O9S | 0.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 5g | 875323786
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Medchemexpress LLC Tamra-PEG3-azide | 1228100-59-1 | 96.4% | 630.69 g/mol | C33H38N6O7 | 10MG
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TAMRA-PEG3-Azide is a red-fluorescent TAMRA dye derivative bearing a three-unit polyethylene glycol (PEG3) spacer and a terminal azide functional group. It is intended for bioorthogonal conjugation to biomolecules via copper-catalyzed or strain-promoted azide-alkyne cycloaddition, offering a fluorescent label with improved solubility and spacer length.
- Red-fluorescent dye with excitation/emission maxima 553/575 nm
- Terminal azide enables CuAAC and SPAAC click chemistry
- PEG3 spacer improves solubility and reduces steric interference
- High purity (≈96.4%) in solid form
- Soluble in methanol at about 12.5 mg/mL (19.82 mM); ultrasonic may be required
- Storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA | 2414913-97-4 | 99.0% | 1 G
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Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate composed of a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. It can be utilized for the synthesis of PROTACs. This product is for research use only and not sold to patients.
- Molecular weight: 562.49
- Formula: C23H29F3N4O9
- Appearance: Solid-liquid mixture
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: 4°C, stored under nitrogen, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture).
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Medchemexpress LLC m-PEG3-Aminooxy | 248275-10-7 | 98.0% | C7H17NO4 | 500 MG
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m-PEG3-Aminooxy is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs consist of two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other the target protein. They leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Used as a PEG-based PROTAC linker
- Facilitates the synthesis of PROTACs
- Involves two ligands connected by a linker
- Utilizes the ubiquitin-proteasome system
- Enables selective degradation of target proteins
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Medchemexpress LLC Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- | 6338-55-2 | 149.19 | 10 G
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NH2-PEG3, also known as PROTAC Linker 35, is a polyethylene glycol (PEG) linker used in the synthesis of PROTACs, including PROTAC (β-NF-JQ1). PROTACs are compounds designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Polyethylene glycol (PEG) linker
- Used in the synthesis of PROTACs
- Facilitates the synthesis of PROTAC (β-NF-JQ1)
- Enables targeted protein degradation via the ubiquitin-proteasome system
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG3-C-Boc | 500MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Azido-PEG3-C-Boc | 500MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Lipoamide-PEG3-Mal | 1314378-19-2 | 99.6% | C25H41N3O7S2 | 1 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Lipoamide-PEG3-Mal is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 1 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Useful for the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Bromoacetamido-PEG3-C2-Boc | 1807537-33-2 | C15H28BrNO6 | 500 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are molecules that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More