Organo-Metalloid Compounds
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Filtered Search Results
AURUM PHARMATECH INC 2-FLUORO-4-TRIMETHYLSIL / 2.5G
NC3180696 2-FLUORO-4-TRIMETHYLSIL / 2.5G
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Medchemexpress LLC Methyl-PEG3-bromide 10g
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Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC N-Boc-PEG5-bromide | 1392499-32-9 | MFCD31536756 | 98.0% | 400.31 g/mol | C15H30BrNO6 | 1 G
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N-Boc-PEG5-bromide is a Boc-protected polyethylene glycol (PEG5) bromide linker reagent used in organic synthesis for assembling antibody-drug conjugate (ADC) and proteolysis-targeting chimera (PROTAC) linkers. It supplies a protected amine and a reactive terminal bromide for nucleophilic substitution and coupling reactions, and is provided at high purity for research use.
- Provides a Boc-protected amine for temporary protection during synthesis.
- Offers a terminal bromide suitable for nucleophilic substitution and coupling reactions.
- PEG5 spacer increases solubility and flexibility in linker constructs.
- High purity appropriate for research and linker assembly.
- Stable under recommended storage conditions for extended shelf life.
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eMolecules 139115-92-7 | Boc-NH-PEG3 | Ambeed | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 5g | 552604531
Boc-NH-PEG3 | Ambeed | 139115-92-7 | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 5g | 552604531
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Medchemexpress LLC Azide-PEG5-Boc | 1415800-41-7 | C17H33N3O7 | 500 MG
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Azide-PEG5-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. PROTACs are designed to selectively degrade target proteins by utilizing the intracellular ubiquitin-proteasome system.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Utilizes the intracellular ubiquitin-proteasome system to degrade target proteins
- For research use only
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Chemscene CHEMSCENE
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5000575745 TETRAETHYL METHYLENEBIS PH 10G
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Chemscene CHEMSCENE
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5000576381 TETRAETHYL METHYLENEBIS P 500G
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Medchemexpress LLC Chloro-PEG5-chloride 25mg
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Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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eMolecules 546-68-9 | Tetraisopropyl orthotitanate | Chem-Impex | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 5kg | 686070058
Tetraisopropyl orthotitanate | Chem-Impex | 546-68-9 | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 5kg | 686070058
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eMolecules 77544-68-4 | Tos-PEG3 | Medchem Express | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 100mg | 515744325
Tos-PEG3 | Medchem Express | 77544-68-4 | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 100mg | 515744325
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Medchemexpress LLC N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid | 2183440-74-4 | 98.1% | C29H55N5O13 | 100 MG
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N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Azide group facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- PROTACs leverage the ubiquitin-proteasome system for selective protein degradation
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g·mol⁻¹ | C10H21N3O5 | 5 G
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Azido-PEG5-alcohol is an azide-terminated polyethylene glycol linker containing five ethylene glycol units and a terminal primary alcohol, used as a water-soluble reagent for bioconjugation and linker synthesis. It is commonly applied in click chemistry and in the construction of antibody-drug conjugates and PROTACs.
- Azide functionality enables CuAAC and SPAAC click reactions.
- Water-soluble PEG5 spacer improves solubility and flexibility.
- Terminal primary alcohol provides a synthetic handle for derivatization.
- Suitable for ADC linker synthesis and PROTAC construction.
- Supplied as a solid with reported purity >97.0%.
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Medchemexpress LLC N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid | 2183440-70-0 | 99.6% | C24H47N5O11 | 25 MG
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N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a versatile click chemistry reagent, facilitating selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
- Functions as a PROTAC linker
- Utilized in PROTAC synthesis
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Medchemexpress LLC Azido-PEG3-C6-Cl | 1625717-44-3 | 95.30% | 293.79 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Azido-PEG3-C6-Cl is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, capable of undergoing both copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Participates in CuAAc reactions with alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 5 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG5-Br is a PEG-based PROTAC linker. It is for research use only and not for sale to patients. This linker can be used in the synthesis of PROTACs, which consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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