Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 99.6% | 369.45 | C19H31NO6 | 10 MG
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BCN-PEG3-OH is a BCN-functionalized PEG linker used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It features a BCN group for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and a three-unit PEG spacer terminating in a hydroxyl group.
- Non-cleavable PEG linker for ADC synthesis
- BCN group enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Three-unit PEG spacer with terminal hydroxyl
- High purity suitable for research applications
- Available in small pack sizes for laboratory use
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Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 250 MG
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Medchemexpress LLC Bromoacetamido-PEG3-NH-Boc | 1421933-39-2 | C15H29BrN2O6 | 5 G
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Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
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Medchemexpress LLC Lipoamide-PEG3-Mal | 1314378-19-2 | 99.6% | C25H41N3O7S2 | 1 MG
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Lipoamide-PEG3-Mal is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Azide-PEG3-Desthiobi 10mg
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Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Azide-PEG3-Desthiobiotin is a click chemistry reagent it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 50 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand. It is used for the synthesis of PROTACs.
- Utilized for the synthesis of PROTACs
- VHL ligand
- Related to cancer targeted therapy
- Inhibitor
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Medchemexpress LLC M-PEG3-OMs | 74654-05-0 | C8H18O6S | 1 G
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m-PEG3-OMs is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mal-PEG5-acid | 1286755-26-7 | ≥97.0% | 25 MG
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Mal-PEG5-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only.
- PEG-based PROTAC linker for chemical synthesis
- Utilizes the ubiquitin-proteasome system for selective protein degradation
- Molecular weight: 389.40
- Chemical formula: C17H27NO9
- Purity: ≥97.0%
- Appearance: Light brown to yellow liquid
- Soluble in DMSO (100 mg/mL)
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Medchemexpress LLC Azido-PEG5-triethoxysilane | 3025193-22-7 | 95.0% | C22H46N4O9Si | 100 MG
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Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound also functions as a click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Furthermore, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with molecules containing DBCO or BCN groups.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Capable of copper-catalyzed azide-alkyne cycloaddition with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups
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Medchemexpress LLC Mal-PEG3-NH2 TFA | 2830214-77-0 | 99.1% | 386.32 g/mol | C14H21F3N2O7 | 25 MG
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Mal-PEG3-NH2 TFA is a linear heterobifunctional polyethylene glycol crosslinker supplied as the trifluoroacetic acid (TFA) salt. It features a maleimide group for selective thiol conjugation and a primary amine for subsequent modification, making it useful as a non-degradable PROTAC linker and general bioconjugation reagent for research applications.
- Maleimide and primary amine functional groups for orthogonal conjugation.
- Supplied as TFA salt for enhanced stability and handling.
- High purity suitable for research-scale bioconjugation (≈99.1%).
- Available in small mg packaging for precision experiments.
- Non-degradable (non-cleavable) linker for stable conjugates.
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Medchemexpress LLC 2-(2-(2-Bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | 100 MG
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Br-PEG3-MS is a PEG-based PROTAC linker employed in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 572245281
Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 572245281
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Medchemexpress LLC O,O'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 100 MG
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This product, Bis-aminooxy-PEG3, is a PEG-based PROTAC linker. It has a molecular weight of 224.25 and appears as a colorless to light yellow liquid.
- Consistent with structure based on ¹H NMR spectrum
- Consistent with structure based on MS
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![Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202875.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Hydroxy-PEG3-(CH2)2-Boc is a Boc-protected, hydroxy-terminated polyethylene glycol linker used as a building block in linker and PROTAC synthesis. Supplied as a white to off-white solid, it has a typical purity of 95.0% and a molecular weight of 278.34 g/mol (CAS 186020-66-6).
- Boc-protected hydroxy-terminated PEG3 linker for synthetic chemistry.
- Typical purity 95.0% by NMR.
- Molecular weight 278.34 g/mol.
- Chemical formula C13H26O6.
- Supplied as a 25 g package for laboratory research use only.
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(c1ccccc1)c1ccccc1 | 1000g | 772451881](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482268.jpg-250.jpg)
eMolecules 58479-61-1 | tert-Butylchlorodiphenylsilane | Ochem Incorporation | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
tert-Butylchlorodiphenylsilane | Ochem Incorporation | 58479-61-1 | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
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