Organo-Metalloid Compounds
- (1)
- (19)
- (141)
- (2)
- (10)
- (1)
- (1)
- (27)
- (20)
- (4)
- (62)
- (96)
- (12)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (3)
- (206)
- (153)
- (2)
- (25)
- (23)
- (13)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (251)
- (85)
- (1)
- (1)
- (20)
- (8)
- (11)
- (30)
- (54)
- (3)
- (10)
- (1)
- (8)
- (2)
- (2)
- (8)
- (4)
- (2)
- (21)
- (2)
- (2)
- (3)
- (5)
- (4)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (5)
- (2)
- (3)
- (1)
- (2)
- (5)
- (4)
- (1)
- (1)
- (3)
- (2)
- (2)
- (2)
- (5)
- (3)
- (3)
- (2)
- (18)
- (3)
- (1)
- (2)
- (4)
- (3)
- (5)
- (1)
- (2)
- (2)
- (2)
- (4)
- (4)
- (1)
- (2)
- (5)
- (6)
- (2)
- (2)
- (4)
- (2)
- (3)
- (4)
- (4)
- (4)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (9)
- (3)
- (4)
- (2)
- (1)
- (1)
- (7)
- (3)
- (5)
- (9)
- (1)
- (3)
- (4)
- (1)
- (7)
- (4)
- (1)
- (4)
- (1)
- (8)
- (1)
- (10)
- (6)
- (3)
- (2)
- (2)
- (4)
- (7)
- (3)
- (2)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (5)
- (9)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (6)
- (6)
- (1)
- (1)
- (2)
- (5)
- (1)
- (1)
- (1)
- (4)
- (1)
- (4)
- (10)
- (2)
- (4)
- (1)
- (3)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (3)
- (1)
- (3)
- (3)
- (2)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (8)
- (3)
- (1)
- (4)
- (1)
- (2)
- (2)
- (3)
- (1)
- (3)
- (8)
- (6)
- (1)
- (3)
- (9)
- (2)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (6)
- (5)
- (3)
- (1)
- (10)
- (2)
- (5)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (8)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (7)
- (3)
- (2)
- (2)
- (8)
- (15)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (2)
- (2)
- (1)
- (2)
- (1)
- (11)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (2)
- (4)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (4)
- (5)
- (3)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (5)
- (3)
- (3)
- (5)
- (3)
- (2)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (1)
- (9)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (2)
- (2)
- (1)
- (8)
- (2)
- (2)
- (2)
- (1)
- (3)
- (1)
- (1)
- (2)
- (2)
- (2)
- (5)
- (3)
- (1)
- (20)
- (4)
- (2)
- (2)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (4)
- (3)
- (1)
- (3)
- (2)
- (5)
- (1)
- (2)
- (1)
- (4)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (4)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (4)
- (2)
- (3)
- (3)
- (2)
- (2)
- (2)
- (2)
- (2)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (4)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (4)
- (2)
- (1)
- (3)
- (2)
- (4)
- (1)
- (14)
- (2)
- (12)
- (1)
- (3)
- (11)
- (2)
- (1)
- (115)
- (4)
- (1)
- (4)
- (2)
- (61)
- (5)
- (1)
- (2)
- (120)
- (15)
- (16)
- (4)
- (2)
- (3)
- (17)
- (177)
- (12)
- (3)
- (1)
- (30)
- (1)
- (3)
- (3)
- (9)
- (1)
- (7)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (1)
- (1)
- (7)
- (9)
- (19)
- (4)
- (60)
- (5)
- (1)
- (21)
- (3)
- (133)
- (6)
- (124)
- (22)
- (31)
- (5)
- (1)
- (2)
- (6)
- (8)
- (68)
- (2)
- (3)
- (6)
- (5)
- (2)
- (8)
- (2)
- (877)
- (1)
- (1)
- (2)
- (14)
- (2)
- (1)
- (6)
- (8)
- (2)
- (4)
- (3)
- (8)
- (3)
- (1)
- (3)
- (12)
- (1)
- (5)
- (2)
- (4)
- (3)
- (10)
- (4)
- (3)
- (5)
- (2)
- (4)
- (7)
- (8)
- (1)
- (1)
- (1)
- (2)
- (3)
- (3)
- (6)
- (6)
- (3)
- (3)
- (3)
- (10)
- (2)
- (2)
- (6)
- (2)
- (1)
- (4)
- (5)
- (1)
- (2)
- (4)
- (4)
- (2)
- (4)
- (5)
- (7)
- (5)
- (4)
- (2)
- (6)
- (3)
- (11)
- (12)
- (1)
- (5)
- (2)
- (5)
- (2)
- (10)
- (2)
- (1)
- (3)
- (2)
- (2)
- (2)
- (1)
- (3)
- (6)
- (3)
- (1)
- (2)
- (4)
- (3)
- (4)
- (2)
- (1)
- (2)
- (10)
- (3)
- (3)
- (2)
- (3)
- (2)
- (12)
- (1)
- (3)
- (7)
- (1)
- (1)
- (4)
- (3)
- (3)
- (2)
- (2)
- (4)
- (6)
- (2)
- (2)
- (5)
- (2)
- (3)
- (2)
- (1)
- (2)
- (4)
- (5)
- (4)
- (1)
- (4)
- (2)
- (2)
- (2)
- (8)
- (7)
- (2)
- (3)
- (2)
- (1)
- (7)
- (11)
- (3)
- (2)
- (1)
- (9)
- (2)
- (1)
- (2)
- (3)
- (2)
- (6)
- (2)
- (2)
- (2)
- (4)
- (4)
- (10)
- (1)
- (2)
- (2)
- (3)
- (3)
- (3)
- (1)
- (2)
- (4)
- (3)
- (5)
- (3)
- (2)
- (7)
- (3)
- (2)
- (2)
- (2)
- (5)
- (2)
- (1)
- (3)
- (1)
- (6)
- (2)
- (4)
- (4)
- (1)
- (4)
- (5)
- (3)
- (6)
- (3)
- (2)
- (2)
- (3)
- (4)
- (3)
- (3)
- (2)
- (3)
- (2)
- (1)
- (3)
- (2)
- (2)
- (2)
- (3)
- (3)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (5)
- (2)
- (2)
- (2)
- (4)
- (2)
- (2)
- (2)
- (1)
- (5)
- (1)
- (8)
- (2)
- (2)
- (2)
- (2)
- (2)
- (3)
- (3)
- (4)
- (2)
- (3)
- (2)
- (3)
- (7)
- (5)
- (4)
- (2)
- (3)
- (2)
- (2)
- (7)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (2)
- (5)
- (2)
- (3)
- (4)
- (2)
- (3)
- (2)
- (1)
- (1)
- (2)
- (6)
- (3)
- (1)
- (1)
- (2)
- (2)
- (3)
- (3)
- (5)
- (3)
- (3)
- (4)
- (2)
- (2)
- (2)
- (2)
- (4)
- (4)
- (6)
- (2)
- (2)
- (10)
- (2)
- (2)
- (2)
- (8)
- (2)
- (1)
- (11)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (8)
- (1)
- (1)
- (3)
- (6)
- (1)
- (1)
- (1)
- (7)
- (3)
- (3)
- (3)
- (3)
- (3)
- (4)
- (4)
- (5)
- (2)
- (3)
- (3)
- (2)
Filtered Search Results
TARGETMOL CHEMICALS INC PS-1145 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM. Purity 99.63%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Aobchem AOBCHEM
5000955423 2-TRIMETHYLSILANYLTHIAZOLE 5G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
(c1ccccc1)c1ccccc1 | 1000g | 772451881](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482268.jpg-250.jpg)
eMolecules 58479-61-1 | tert-Butylchlorodiphenylsilane | Ochem Incorporation | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
tert-Butylchlorodiphenylsilane | Ochem Incorporation | 58479-61-1 | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC PS-1145
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PS-1145 is a specific IKK inhibitor with IC50 of 88 nM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC NVR 3-778 1445790-55-5 1mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
NVR 3-778 (CAS 1445790-55-5) is a small-molecule modulator targeting the hepatitis B virus (HBV) core protein It is designed to interfere with HBV capsid assembly thereby inhibiting viral genome encapsidation and replication NVR 3-778 exerts its biological activity primarily by disrupting capsid formation and reducing viral replication In in vitro studies NVR 3-778 demonstrates antiviral inhibition with a half-maximal inhibitory concentration (IC50) reported in the low micromolar range Based on these pharmacological properties NVR 3-778 holds research potential in the investigation of HBV biology and the development of alternative therapeutic approaches for chronic hepatitis B infection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC PS-1145 431898-65-6 5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PS-1145 (CAS 431898-65-6) is a selective inhibitor of I B kinase (IKK) with an IC50 of 88 nM IKK is a critical component of the upstream NF- B signaling pathway regulating cellular responses to inflammation In vitro studies have demonstrated that PS-1145 blocks TNF -induced NF- B activation in multiple myeloma (MM) cells in a dose- and time-dependent manner increases I B protein levels suppresses IL-6-mediated anti-apoptotic effects and inhibits expression of ICAM-1 Additionally PS-1145 reduces IL-6 secretion from bone marrow stromal cells (BMSCs) and partially limits MM cell proliferation In vivo PS-1145 has been shown to induce apoptosis in DMBA-induced skin tumors in rats by inhibiting NF- B and VEGF activity The compound remains in the preclinical research stage
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC 4-fluoro-3-(4-hydroxypiperidin-1-yl)sulfonyl-N-(3,4,5-trifluorophenyl)benzamide | 1445790-55-5 | 99.9% | 432.39 g/mol | C18H16F4N2O4S | 10MM 1ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
NVR 3-778 is a small-molecule hepatitis B virus (HBV) capsid assembly modulator (CAM) of the sulfamoylbenzamide class with reported oral bioavailability and anti-HBV activity. It is supplied for research use as a high-purity solid and is commonly provided as 10 mM stock solutions in DMSO for in vitro assays.
- First-in-class capsid assembly modulator for HBV research.
- Orally bioavailable compound with reported antiviral activity.
- High purity (≈99.9%) suitable for analytical and biological studies.
- Molecular weight 432.39 g/mol; formula C18H16F4N2O4S.
- Available as solid and as 10 mM DMSO solution for convenience in assays.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC NVR 3-778
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
NVR 3-778 belonging to the SBA (sulfamoylbenzamide) class is a first-in-Class and oral bioavailable HBV CAM (capsid assembly modulator) NVR 3-778 exhibits anti-HBV activity
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC PLATYCODIN D 25MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Platycodin D may stimulate TNF-(alpha) synthesis or inhibit degradation of TNF-(alpha) mRNA. Platycodin D (10/30 uM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA). Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization. purity: 99%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chem-Impex International, Inc. 1-(Trimethylsilyl)imidazole | MFCD00005280 | 250G
1-(Trimethylsilyl)imidazole, MFCD00005280, 250G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chem-Impex International, Inc. 1-(Trimethylsilyl)imidazole | MFCD00005280 | 100G
1-(Trimethylsilyl)imidazole, MFCD00005280, 100G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC PS-1145 | 431898-65-6 | 99.7% | 322.75 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PS-1145 is an IκB kinase (IKK) inhibitor with an IC50 of 88 nM. It blocks TNFα-induced NF-κB activation in MM cells by inhibiting IκBα phosphorylation. Dexamethasone enhances the blockade of NF-κB activation by PS-1145.
- Blocks TNFα-induced NF-κB activation.
- Inhibits IκBα phosphorylation.
- Enhances blockade of NF-κB activation by Dexamethasone.
- Blocks protective effect of IL-6 against Dex-induced apoptosis.
- Inhibits TNFα-induced intracellular adhesion molecule (ICAM)-1 expression.
- Inhibits IL-6 secretion from bone marrow stromal cells.
- Inhibits proliferation of MM cells adherent to bone marrow stromal cells.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Ak-778-xxmu | 1227045-76-2 | MFCD16882561; MFCD08272115 | 100.0% | 392.83 g/mol | C22H17ClN2O3 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
A potent small-molecule research reagent that antagonizes DNA binding protein 2 (ID2), with demonstrated binding (KD ≈129 nM) and cellular activity inhibiting glioma cell migration and inducing apoptosis.
- Small-molecule antagonist of DNA binding protein 2 (ID2) with KD ≈129 nM.
- Inhibits glioma cell migration and invasion, and induces apoptosis in cell models.
- High purity (99.96%) and off-white to light yellow solid appearance.
- Molecular formula C22H17ClN2O3; molecular weight 392.83 g/mol.
- Recommended solvent: DMSO, 100 mg/mL (use ultrasonic and freshly opened DMSO).
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solution store at -80°C.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Ak-778-xxmu | 1227045-76-2 | 100.0% | C22H17ClN2O3 | 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
AK-778-XXMU is a small-molecule antagonist of DNA binding inhibitor 2 (ID2) used for research applications. It binds ID2 with a reported KD of 129 nM, inhibits glioma cell migration and invasion, induces apoptosis, and modulates ID2-KDR signaling to affect VEGFA, MMP2/9, and PTEN.
- Potent ID2 binding (KD 129 nM).
- Demonstrated inhibition of glioma cell migration and invasion.
- Induces apoptosis in glioma cell lines.
- Modulates angiogenesis and invasion-related signaling pathways.
- High chemical purity (99.96%).
- Soluble in DMSO at 100 mg/mL; ultrasonic may be required.
- Stable as a powder at -20°C for long-term storage.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC NVR 3-778 1445790-55-5 10mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
NVR 3-778 (CAS 1445790-55-5) is a small-molecule modulator targeting the hepatitis B virus (HBV) core protein It is designed to interfere with HBV capsid assembly thereby inhibiting viral genome encapsidation and replication NVR 3-778 exerts its biological activity primarily by disrupting capsid formation and reducing viral replication In in vitro studies NVR 3-778 demonstrates antiviral inhibition with a half-maximal inhibitory concentration (IC50) reported in the low micromolar range Based on these pharmacological properties NVR 3-778 holds research potential in the investigation of HBV biology and the development of alternative therapeutic approaches for chronic hepatitis B infection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More