Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Mal-PEG3-NH2 TFA | 2830214-77-0 | 99.1% | 386.32 g·mol⁻¹ | C14H21F3N2O7 | 10 MG
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Mal-PEG3-NH2 TFA is a linear heterobifunctional polyethylene glycol crosslinker supplied as the trifluoroacetic acid (TFA) salt. It contains a maleimide group at one end and a primary amine at the other, enabling selective conjugation to thiols and amines. It is provided as a non-degradable (non-cleavable) linker commonly used in PROTAC and ADC linker design and general bioconjugation.
- Maleimide and primary amine functional groups for thiol and amine conjugation.
- Non-degradable, non-cleavable linker suitable for PROTAC and ADC applications.
- High reported purity of 99.07%.
- Molecular weight 386.32 g·mol⁻¹.
- Available in multiple sizes including 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.
- Supplied as the trifluoroacetic acid (TFA) salt.
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Medchemexpress LLC Lipoamide-PEG3-mal | 1314378-19-2 | 99.6% | C25H41N3O7S2 | 10MG
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Lipoamide-PEG3-Mal is a PEG-based linker that combines a lipoamide (lipoic acid derivative) moiety with a terminal maleimide. It is supplied for research use as a building block in the synthesis of PROTACs and other bioconjugates, providing flexible spacing and a thiol-reactive handle for selective conjugation.
- Peg3 spacer provides flexibility and improved solubility.
- Lipoamide moiety offers a bio-relevant functional group for linkage.
- Maleimide group enables rapid and selective thiol conjugation.
- High reported purity suitable for synthetic applications.
- Available in small, research-friendly package sizes.
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Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 99.6% | 369.45 | C19H31NO6 | 10 MG
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BCN-PEG3-OH is a BCN-functionalized PEG linker used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It features a BCN group for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and a three-unit PEG spacer terminating in a hydroxyl group.
- Non-cleavable PEG linker for ADC synthesis
- BCN group enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Three-unit PEG spacer with terminal hydroxyl
- High purity suitable for research applications
- Available in small pack sizes for laboratory use
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Medchemexpress LLC N- Azido-PEG3 -N-bis | 250MG
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N- Azido-PEG3 -N-bis | 250MG
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eMolecules 1204669-57-7 | 3-(4-(2-AMINOETHYLAMINO)-1,2,5-OXADIAZOL-3-YL)-4-(3-BROMO-4-FLUOROPHENYL)-1,2,4-OXADIAZOL-5(4H)-ONE HI | AstaTech | MFCD27996217 | 513.066 | C12H11BrFIN6O3 | 95.000 | I.NCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1 | 1g | 410712794
3-(4-(2-AMINOETHYLAMINO)-1,2,5-OXADIAZOL-3-YL)-4-(3-BROMO-4-FLUOROPHENYL)-1,2,4-OXADIAZOL-5(4H)-ONE HI | AstaTech | 1204669-57-7 | MFCD27996217 | 513.066 | C12H11BrFIN6O3 | 95.000 | I.NCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1 | 1g | 410712794
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Medchemexpress LLC Bis-PEG3-NHS ester | 1314378-16-9 | MFCD20227484 | 97.0% | 444.39 g·mol⁻¹ | C18H24N2O11 | 100 MG
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Bis-PEG3-NHS ester is a noncleavable, three-unit polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester termini for amine coupling. It is intended for antibody-agent conjugation and related bioconjugation chemistries, enabling formation of stable amide bonds to primary amines on proteins or small molecules.
- Noncleavable three-unit PEG spacer suitable for antibody-agent conjugation and bioconjugation.
- Two NHS ester reactive termini for efficient amine coupling to primary amines.
- White to off-white solid, convenient for bench handling.
- High purity (97.0%) with CAS 1314378-16-9 and formula C18H24N2O11.
- Storage: powder at -20°C (stable up to 3 years); in solvent at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC M-PEG5-acid | 81836-43-3 | MFCD20926398 | 95.0% | 280.31 g/mol | C12H24O7 | 1 G
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m-PEG5-acid is a monomethylated polyethylene glycol (PEG) linker terminated with a carboxylic acid group, used as a short spacer in the synthesis of PROTACs and other bioconjugates. It provides a PEG5 (approximately five ethylene oxide units) spacer with a reactive carboxylic acid for standard coupling chemistries.
- Short monomethylated PEG5 spacer with terminal carboxylic acid.
- Useful as a linker in PROTAC and conjugate synthesis.
- Molecular weight ~280.31 g/mol and formula C12H24O7.
- Typical purity around 95.0%.
- Light yellow to light brown liquid; density ~1.107 g/cm3.
- Store sealed, away from moisture; use cold storage for solutions.
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | Ambeed | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 100mg | 506388578
NH2-PEG3-C2-Boc | Ambeed | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 100mg | 506388578
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Medchemexpress LLC Bromoacetamido-PEG3-azide | 940005-81-2 | ≥97.0% | C10H19BrN4O4 | 50 MG
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Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent containing an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC M-PEG3-azide | 74654-06-1 | 98.0% | C7H15N3O3 | 500 MG
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m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Participates in CuAAc reactions with Alkyne groups
- Participates in SPAAC reactions with DBCO or BCN groups
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Medchemexpress LLC OSI-930 | 728033-96-3 | MFCD11100358 | 98.3% | 443.44 | C22H16F3N3O2S | 10 MG
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OSI-930 is a small-molecule tyrosine kinase inhibitor selective for c-Kit, KDR (VEGFR2), and CSF-1R (c-Fms), provided as a solid for research use. It exhibits in vitro potency with reported IC50s of ~80 nM (Kit), 9 nM (KDR), and 15 nM (CSF-1R) and has shown antitumor activity in preclinical models.
- Selective inhibition of c-Kit, KDR, and CSF-1R.
- Low nanomolar potency against VEGFR2 (KDR).
- Useful for kinase inhibition and cancer biology research.
- High listed purity (≈98.3%).
- Supplied as a solid in small-scale quantities suitable for laboratory studies.
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Medchemexpress LLC Bis-PEG5-acid 10g | 439114-13-3 | 338.35 g/mol | C14H26O9 | 10 G
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Bis-PEG5-acid is a polyethylene glycol (PEG) linker with two terminal carboxylic acid groups used to assemble PROTACs and other bifunctional molecules. The hydrophilic spacer increases aqueous solubility and provides flexible separation between ligands for conjugation chemistry.
- Two terminal carboxylic acid groups for conjugation.
- Hydrophilic PEG spacer improves solubility in aqueous media.
- Flexible linker suitable for PROTAC and bifunctional molecule assembly.
- Available in multiple package sizes including 10 G.
- Solid material with white to yellow appearance.
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![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202088.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG
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Aminooxy-PEG3-azide is a PEG-based bifunctional linker containing an aminooxy (oxyamine) group and an azide group. It is used as a non-cleavable three-unit PEG spacer for antibody-drug conjugate (ADC) and PROTAC synthesis, and as an azide reagent for click chemistry reactions such as CuAAC and SPAAC.
- Bifunctional aminooxy and azide groups for oxime ligation and click chemistry.
- Non-cleavable three-unit PEG spacer suitable for ADC and PROTAC linker installation.
- Purity 95.0% and molecular weight 234.25 g/mol.
- Appearance colorless to light yellow liquid for easy handling.
- Storage: pure form -20°C (stable 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in small pack sizes, including 10 mg for small-scale synthesis.
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eMolecules 96105-72-5 | 2-Amino-3,3,3-trifluoropropanoic acid hydrochloride | Combi-Blocks, Inc. | MFCD04973034 | 179.520 | C3H5ClF3NO2 | 95.000 | Cl.NC(C(O)=O)C(F)(F)F | 5g | 603141958
2-Amino-3,3,3-trifluoropropanoic acid hydrochloride | Combi-Blocks, Inc. | 96105-72-5 | MFCD04973034 | 179.520 | C3H5ClF3NO2 | 95.000 | Cl.NC(C(O)=O)C(F)(F)F | 5g | 603141958
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Medchemexpress LLC Bromoacetamido-PEG3-NH-Boc | 1421933-39-2 | C15H29BrN2O6 | 5 G
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Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
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