Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC THP-PEG5-OH | 146395-14-4 | 25 MG
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also described as a reference compound.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Reference compound
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 100 MG
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
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Medchemexpress LLC BnO-PEG5-OH | 57671-28-0 | 98.6% | 328.40 g/mol | C17H28O6 | 10 G
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BnO-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker used to connect ligands in proteolysis targeting chimera (PROTAC) synthesis, providing spacer functionality and flexibility to aid target engagement and E3 ligase recruitment.
- Polyethylene glycol spacer with five ethylene glycol units.
- High purity suitable for research applications.
- Liquid, colorless to light yellow, density ≈ 1.10 g/cm3.
- Stable under recommended storage conditions for pure material and in solvent.
- Available in common laboratory pack sizes, including 10 g.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ethanol, 2-[2-(2-aminoethoxy)ethoxy]- | 6338-55-2 | 149.19 | 10 G
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NH2-PEG3, also known as PROTAC Linker 35, is a polyethylene glycol (PEG) linker used in the synthesis of PROTACs, including PROTAC (β-NF-JQ1). PROTACs are compounds designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Polyethylene glycol (PEG) linker
- Used in the synthesis of PROTACs
- Facilitates the synthesis of PROTAC (β-NF-JQ1)
- Enables targeted protein degradation via the ubiquitin-proteasome system
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Medchemexpress LLC Azido-PEG3-C-Boc | 500MG
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Azido-PEG3-C-Boc | 500MG
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Medchemexpress LLC Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
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Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
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Medchemexpress LLC Lipoamide-PEG3-Mal | 1314378-19-2 | 99.6% | C25H41N3O7S2 | 1 MG
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Lipoamide-PEG3-Mal is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 1 G
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Useful for the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC O,O'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 100 MG
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This product, Bis-aminooxy-PEG3, is a PEG-based PROTAC linker. It has a molecular weight of 224.25 and appears as a colorless to light yellow liquid.
- Consistent with structure based on ¹H NMR spectrum
- Consistent with structure based on MS
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Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G
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Hydroxy-PEG3-(CH2)2-Boc is a Boc-protected, hydroxy-terminated polyethylene glycol linker used as a building block in linker and PROTAC synthesis. Supplied as a white to off-white solid, it has a typical purity of 95.0% and a molecular weight of 278.34 g/mol (CAS 186020-66-6).
- Boc-protected hydroxy-terminated PEG3 linker for synthetic chemistry.
- Typical purity 95.0% by NMR.
- Molecular weight 278.34 g/mol.
- Chemical formula C13H26O6.
- Supplied as a 25 g package for laboratory research use only.
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Medchemexpress LLC Bis-PEG5-NHS ester | 756526-03-1 | 99.8% | 532.50 g/mol | C22H32N2O13 | 25 MG
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Bis-PEG5-NHS ester is a bifunctional PEG-based cleavable NHS-activated ester used for conjugation to primary amines in the synthesis of antibody-drug conjugates (ADCs), PROTACs, and other bioconjugates. Supplied as a solid for research use, it facilitates PEGylation and formation of cleavable linkers in medicinal chemistry and chemical biology workflows.
- Cleavable PEG5 NHS ester for selective amine conjugation.
- Suitable for ADC and PROTAC linker synthesis.
- High purity, suitable for synthetic applications.
- Molecular weight 532.50 g/mol, chemical formula C22H32N2O13.
- Available in small-scale research quantities, e.g. 25 MG.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (E)-Cyclooct-2-en-1-yl (2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)carbamate | 98.4% | 344.45 | C17H32N2O5 | 10 MG
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TCO-PEG3-NH2 is a click-chemistry reagent composed of a trans-cyclooctene (TCO) group linked to a three-unit polyethylene glycol spacer terminating in a primary amine. It enables fast bioorthogonal inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine-functionalized partners and amine-mediated conjugation for site-specific labeling of biomolecules.
- Enables rapid iEDDA bioorthogonal chemistry for fast conjugation.
- Terminal primary amine allows amide bond formation with carboxyl groups.
- Three-unit PEG spacer improves aqueous solubility and reduces steric hindrance.
- Suitable for site-specific labeling and bioconjugation workflows.
- Typically supplied as a small solid quantity for laboratory use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-, (1α,8α,9ẞ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BCN-PEG3-OH is a BCN-functionalized PEG linker intended for bioconjugation and antibody-drug conjugate (ADC) synthesis. The reagent contains a bicyclo[6.1.0]nonyne (BCN) group that reacts with azides via strain-promoted alkyne-azide cycloaddition (SPAAC), enabling copper-free click chemistry in aqueous conditions.
- Non-cleavable four-unit PEG linker suitable for ADC construction.
- Enables strain-promoted alkyne-azide cycloaddition with azide-functionalized molecules.
- High reported purity for reliable conjugation performance.
- Available in multiple pack sizes, including small research quantities.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 2-Trimethylsilanylthiazole | ≥97% | CAS 79265-30-8 | C6H11NSSi | 5g
2-Trimethylsilanylthiazole | ≥97% | CAS 79265-30-8 | C6H11NSSi | 5g
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 58479-61-1 | tert-Butylchlorodiphenylsilane | Ochem Incorporation | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
tert-Butylchlorodiphenylsilane | Ochem Incorporation | 58479-61-1 | MFCD00000497 | 274.860 | C16H19ClSi | 98.000 | CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1 | 1000g | 772451881
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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