Dimethyl Sulfoxide
Apexbio Technology LLC AM1241(Synonyms: AM-1241, CB2 receptor agonist AM1241, Cannabinoid receptor CB2 agonist AM1241, AM 1241), 10mM (in 1mL DMSO), CAS: 444912-48-5.
AM1241 (CAS number 444912-48-5) is a selective agonist of the cannabinoid receptor type 2 (CB2) a G protein-coupled receptor encoded by the CNR2 gene CB2 receptors modulate inflammation and neuropathic pain pathways outside the central nervous system In vitro studies suggest stereoisomer-dependent activities specifically the S-enantiomer demonstrates higher functional potency toward human and rodent CB2 receptors compared to the R-enantiomer In animal models AM1241 administration reduces neuropathic pain phenotypes including hyperalgesia and allodynia and shows potential for delaying disease progression in an ALS (amyotrophic lateral sclerosis) mouse model Currently AM1241 remains a valuable investigational tool in preclinical pain and neurodegeneration research
