Dimethyl Sulfoxide
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Apexbio Technology LLC Febuxostat 144060-53-7 10mM (in 1mL DMSO)
Febuxostat (CAS 144060-53-7) is a non-purine selective inhibitor of xanthine oxidase (XO) an enzyme involved in purine metabolism responsible for producing uric acid and reactive oxygen species (ROS) It exerts its inhibitory action by noncompetitive binding at the molybdenum-pterin active center of XO effectively inhibiting both its oxidized and reduced forms Compared to allopurinol febuxostat demonstrates notably higher potency with a reported IC50 of 1 8 nM versus 2 9 M Febuxostat is utilized in clinical and preclinical research exploring hyperuricemia gout and associated metabolic disorders
